NSFIB - Overview: Nonalcoholic Steatohepatitis (NASH)-FibroTest, Serum and Plasma
Diagnosis and the follow-up of liver fibrosis, steatosis, and inflammation Estimating hepatic fibrosis Assessing inflammation for metabolic diseases Assessing severity of nonalcoholic steatohepatitis (NASH) in patients with...
CDSP - Overview: Celiac Disease Serology Cascade, Serum
Evaluating patients suspected of having celiac disease, including patients with compatible symptoms, patients with atypical symptoms, and individuals at increased risk (family history, previous diagnosis with associated disease, positivity...
ESTF - Overview: Estrogens, Estrone (E1) and Estradiol (E2), Fractionated, Serum
Simultaneous high-sensitivity determination of serum estrone and estradiol levels Situations requiring either higher sensitivity estradiol measurement, estrone measurement, or both, including -As part of the diagnosis and workup of...
Providing a genetic evaluation for patients with a personal or family history suggestive of atypical hemolytic uremic syndrome (aHUS), thrombotic microangiopathy (TMA), or complement 3 glomerulopathy (C3G) Establishing a diagnosis of...
SCCNP - Overview: Severe Congenital and Cyclic Neutropenia Gene Panel, Varies
Providing a genetic evaluation for patients with a personal or family history suggestive of severe congenital neutropenia and/or cyclic neutropenia Establishing a diagnosis of an inherited congenital neutropenia and, in some cases,...
PINP - Overview: Procollagen I Intact N-Terminal, Serum
Aiding in monitoring antiresorptive and anabolic therapy in patients with osteoporosis An adjunct in the assessment of conditions associated with increased bone turnover, such as Paget disease This test should not be used as a screening...
PIT1 - Overview: PIT-1 Immunostain, Technical Component Only
Classification of pituitary adenomas
POU2F - Overview: POU2F3 Immunostain, Technical Component Only
Diagnosis of a variant of small cell lung carcinoma
TTIGS - Overview: Tetanus Toxoid IgG Antibody, Serum
Assessing antibody response to the tetanus toxoid vaccine, which should be performed at least 3 weeks after immunization Aiding in the evaluation of immunodeficiency This test should not be used to diagnose tetanus infection.
Identification of breast carcinoma including triple negative breast cancer
TRYPN - Overview: Trypsin Immunostain, Technical Component Only
Identifying cells with acinar differentiation in the pancreas
TFE3I - Overview: Transcription Factor E3 (TFE3) Immunostain, Technical Component Only
Assessment of transcription factor E3 expression
ZONI - Overview: Zonisamide, Serum
Monitoring zonisamide therapy; recommended for all patients to ensure appropriate dosing Assessing medication compliance
PFK1 - Overview: Phosphofructokinase Enzyme Activity, Blood
Evaluation of individuals with Coombs-negative nonspherocytic hemolytic anemia Evaluation of individuals with exercise intolerance or myopathy Genetic studies in families with phosphofructokinase deficiency
AK1 - Overview: Adenylate Kinase Enzyme Activity, Blood
Evaluation of chronic nonspherocytic hemolytic anemia
CD273 - Overview: CD273 (PD-L2) Immunostain, Technical Component Only
Differentiation of primary mediastinal large B-cell lymphoma from diffuse large B cell-lymphoma
PTH - Overview: Parathyroid Hormone (PTH) Immunostain, Technical Component Only
Identification of parathyroid glands
PRLI - Overview: Prolactin (PRL) Immunostain, Technical Component Only
Subclassification of pituitary adenomas
RB1 - Overview: Retinoblastoma Protein (Rb) Immunostain, Tech Only
Aids in the identification of high-grade neuroendocrine carcinomas and small cell carcinomas
CDKP1 - Overview: CD68 (KP1) Immunostain, Tissue, Technical Component Only
Aiding in the identification of histocytic and myeloid lineage cells
CD13 - Overview: CD13 Immunostain, Technical Component Only
Marker of myeloid lineage
SORD - Overview: Sorbitol and Xylitol, Quantitative, Random, Urine
Screening for sorbitol dehydrogenase deficiency-related neuropathy
TLE1 - Overview: TLE-1 Immunostain, Technical Component Only
Aids in the identification of synovial sarcoma
TCRF1 - Overview: T-Cell Receptor Beta (TCR Beta F1) Immunostain, Technical Component Only
Classification of lymphomas
TTFSP - Overview: Thyroid Transcription Factor (SPT24) Immunostain, Technical Component Only
Part of a panel of immunostains to identify the primary site for carcinomas of unknown origin
HNF1B - Overview: Hepatocyte Nuclear Factor 1Beta Immunostain, Technical Component Only
Diagnosis of ovarian clear cell carcinoma and endometrial clear cell carcinoma
HALO - Overview: Haloperidol, Serum
Optimizing haloperidol dosage Monitoring patient compliance Assessing toxicity
HEPBS - Overview: Hepatitis B Surface (HBs) Antigen Immunostain, Technical Component Only
Aiding in the identification of hepatitis B infection (carrier state)
GRANB - Overview: Granzyme B Immunostain, Technical Component Only
Classification of lymphomas
GAB1 - Overview: GRB2-Associated Binding Protein 1 (GAB1) Immunostain, Technical Component Only
Identification and differentiation of medulloblastomas
KM55 - Overview: Galactose Deficient IgA1 (KM55) Immunostain, Technical Component Only
Identification of Galactose deficient IgA1 by KM55, useful in the diagnosis of IgA nephropathy
HAEVI - Overview: Hemolytic Anemia Interpretation
Interpretation of the results for the evaluation of hemolytic anemia Evaluation of lifelong or inherited hemolytic anemias, including red cell membrane disorders, unstable or abnormal hemoglobin variants, and red cell enzyme disorders
FGFRC - Overview: Fibroblast Growth Factor Receptor 1, Immunostain, Technical Component Only
Classification of a subset of lung squamous cell carcinoma
F2ISO - Overview: F2-Isoprostanes, Random, Urine
Assessment of in vivo lipid peroxidation Considered to be an index of systemic oxidative stress over time
UE3 - Overview: Estriol, Unconjugated, Serum
As an adjunct biomarker in the prenatal diagnosis of disorders of fetal steroid metabolism, including Smith-Lemli-Opitz syndrome (1,2) and X-linked ichthyosis (placental sulfatase deficiency disorders) Evaluating primary or secondary fetal...
EXT2 - Overview: Exostosin 2 (EXT2) Immunostain, Technical Component Only
Identification of exostosin 2 associated membranous nephropathy
PBUCR - Overview: Lead/Creatinine Ratio, Random, Urine
Detecting clinically significant lead exposure, a toxic heavy metal, using random urine specimens
LFABP - Overview: Liver Fatty Acid-Binding Protein (L-FABP) Immunostain, Technical Component Only
Classification of hepatic adenomas
IGAI - Overview: IgA Immunostain, Technical Component Only
Aiding in the classification of lymphomas and multiple myeloma
PBUOE - Overview: Lead Occupational Exposure, Random, Urine
Detecting clinically significant lead exposure due to occupational exposure This test is not a substitute for blood lead screening.
LUTHI - Overview: Luteinizing Hormone (LH) Beta Immunostain, Technical Component Only
Classification of pituitary adenomas
Aiding in the diagnosis of multiple sclerosis and other central nervous system inflammatory conditions as a part of a profile
INSM1 - Overview: Insulinoma-Associated Protein 1 (INSM1), Immunostain, Technical Component Only
Identification of neuroendocrine tumors
UIOD - Overview: Iodine, 24 Hour, Urine
Assessing iodine toxicity or recent exposure in a 24-hour urine collection Monitoring iodine excretion rate as index of replacement therapy
ASCL1 - Overview: Achaete-Scute Homolog 1 (ASCL1) Immunostain, Technical Component Only
Identification of the presence of achaete-scute homolog 1 (ASCL1)
AACYL - Overview: Aminoacylase-1 Deficiency, Urine
Follow-up quantitation of abnormal organic acid elevations of N-acetylated amino acids, in particular N-acetylalanine, N-acetylglycine, N-acetylmethionine, and N-acetylglutamic acid Diagnosis of individuals with aminoacylase-1...
ABCRS - Overview: Alpha/Beta Crystallin IHC, Technical Component Only
Characterization of neuroectodermal tumors
APPI - Overview: Amyloid Precursor Protein (APP) Immunostain, Technical Component Only
Aids in the identification of amyloid precursor protein present in Alzheimer disease
ALP - Overview: Alkaline Phosphatase, Serum
Diagnosing and monitoring treatment of liver, bone, intestinal, and parathyroid diseases
SMACN - Overview: Actin, Smooth Muscle (SMActin) Immunostain, Technical Component Only
Identification of cells expressing the alpha-smooth muscle isoform of actin
Hypersensitivity Testing and Initial Patient Management Algorithm 1. Saag M, Balu R, Phillips E, et al. High sensitivity of human leukocyte antigen-b*5701......
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G U ID E D ’EXPÉD ITIO N IN TERN ATIO N ALEENVOYER DES TESTS À LA MAYO CLINIC DEPUIS LE MONDE ENTIER 2 | GUIDE D’EXPÉDITION INTERNATIONALE TABLE DES MATIÈRES EXPÉDIER AUX ÉTATS-UNIS DEPUIS LE MONDE ENTIER 3 Avant...
Pediatric neuro-oncology informative cases - Insights
Neuro-oncology is a complex field undergoing rapid changes with the advancement and evolution of sophisticated genetic testing. Evidence continues to grow in support of broad molecular and cytogenetic analysis for patients with brain...
The diagnosis of Myeloproliferative Neoplasm (MPN) must include an integrated approach and combine the clinical findings with laboratory results. In our latest “Hot Topic,” Rong He, M.D., discusses the subclassification of MPNs and the use...
MCL Autoimmune Axonal Neuropathy A Comprehensive Testing Approach MC2775425
MCL Autoimmune Axonal Neuropathy Comprehensive Testing Approach NEUROLOGY AUTOIMMUNE AXONAL NEUROPATHY COMPREHENSIVE TESTING APPROACH Patients neuropathy variable sensory motor disturbance loss exaggerated