RAVU - Overview: Ravulizumab, Serum

Assessing the response to ravulizumab therapy Assessing the need for dose escalation Evaluating the potential for dose deescalation or discontinuation of therapy in remission states Monitoring patients who need to be above a certain...

H2MT - Overview: HER2 Amplification, Miscellaneous Tumor, FISH, Tissue

Guiding cancer therapy, as patients with HER2 amplification may be candidates for therapies that target the human epidermal growth factor receptor 2 (HER2) protein (eg, trastuzumab [Herceptin], pertuzumab) Confirming the presence of HER2...

MPNR - Overview: Myeloproliferative Neoplasm, JAK2 V617F with Reflex to CALR and MPL, Varies

Aiding in the distinction between a reactive cytosis and a chronic myeloproliferative disorder Evaluating for variants in JAK2, CALR, and MPL genes in an algorithmic process

MCM24 - Overview: Mast Cell Mediators, 24 Hour, Urine

Evaluating patients at risk for mast cell activation syndrome (eg, systemic mastocytosis) using 24-hour urine collections

C9ORF - Overview: C9orf72 Hexanucleotide Repeat, Molecular Analysis, Varies

Molecular confirmation of clinically suspected cases of c9FTD/ALS, frontotemporal dementia (FTD), or amyotrophic lateral sclerosis (ALS) Presymptomatic testing for individuals with a family history of c9FTD/ALS and a documented expansion...

CRDPU - Overview: Creatine Disorders Panel, Random, Urine

Evaluating patients with a clinical suspicion of arginine:glycine amidinotransferase deficiency, guanidinoacetate methyltransferase deficiency, and creatine transporter deficiency

HPRP - Overview: Helicobacter pylori with Clarithromycin Resistance Prediction, Molecular Detection, PCR, Tissue

Aiding in the diagnosis of Helicobacter pylori infection and prediction of clarithromycin resistance or susceptibility directly from gastric biopsies

GNBLC - Overview: Bleeding Disorders, Comprehensive Gene Panel, Next-Generation Sequencing, Varies

Evaluating hereditary bleeding in patients with a personal or family history suggestive of a hereditary bleeding disorder Confirming a hereditary bleeding disorder diagnosis with the identification of a known or suspected disease-causing...

PSGN - Overview: Plasminogen Activity, Plasma

Evaluating patients with ligneous conjunctivitis (strong association with homozygous plasminogen deficiency) Evaluating fibrinolysis, in combination with other components of the fibrinolytic system (fibrinogen, tissue...

MALCT - Overview: Plasmodium Percent Parasitemia Reflex, Varies

Calculating percent parasitemia, which can be used to predict prognosis and monitor response to treatment for patients with malaria

PFK1 - Overview: Phosphofructokinase Enzyme Activity, Blood

Evaluation of individuals with Coombs-negative nonspherocytic hemolytic anemia Evaluation of individuals with exercise intolerance or myopathy Genetic studies in families with phosphofructokinase deficiency

RSVAB - Overview: Respiratory Syncytial Virus (RSV) In Situ Hybridization, Technical Component Only

Aids in the identification of respiratory syncytial viral infection

CDKP1 - Overview: CD68 (KP1) Immunostain, Tissue, Technical Component Only

Aiding in the identification of histocytic and myeloid lineage cells

CD13 - Overview: CD13 Immunostain, Technical Component Only

Marker of myeloid lineage

SOX11 - Overview: SOX11 Immunostain, Technical Component Only

Identification of mantle cell lymphomas

TGLBF - Overview: Triglycerides, Body Fluid

Distinguishing between chylous and nonchylous effusions Measurement of triglycerides in body fluids as a surrogate for chylomicrons

TTSC - Overview: Thrombin Time (Bovine), Plasma

Detecting or excluding the presence of heparin or heparin-like anticoagulants (which act by enhancing antithrombin's inhibition of thrombin and other procoagulant enzymes) when used in conjunction with the reptilase time (RT) in evaluating...

SMAT - Overview: Smooth Muscle Antibody Titer, Serum

Antibody titer testing as a part of the evaluation of patients with hepatitis of unknown origin associated with hypergammaglobulinemia and/or abnormal liver enzymes

2DIS - Overview: Human Leukocyte Antigens (HLA)-DR-DQ Disease Association Typing Low Resolution, Blood

Determining class II human leukocyte antigens (HLA) to identify potential disease associations or markers for drug hypersensitivity

MTAP - Overview: Methylthioadenosine Phosphorylase (MTAP) Immunostain, Tech Only

Aiding in the diagnosis of malignant mesothelioma

AREC - Overview: Androgen Receptor Immunostain, Technical Component Only

Identification of tumors that express androgen receptor

ALP - Overview: Alkaline Phosphatase, Serum

Diagnosing and monitoring treatment of liver, bone, intestinal, and parathyroid diseases

BRAFV - Overview: BRAF V600E Immunostain, Technical Component Only

Identification of BRAF V600E-mutated protein

BVRNA - Overview: Bacterial Vaginosis, Nucleic Acid Amplification, Vaginal

Aid for diagnosis of bacterial vaginosis This test is not intended for use in medico-legal applications.

C9FX - Overview: C9 Complement, Functional, Serum

Diagnosis of C9 deficiency Investigation of a patient with a low total (hemolytic) complement level

FACTV - Overview: Coagulation Factor V Activity Assay, Plasma

Diagnosing congenital deficiencies (rare) of coagulation factor V Evaluating acquired deficiencies associated with liver disease, factor V inhibitors, myeloproliferative disorders, and intravascular coagulation and fibrinolysis...

CD71 - Overview: CD71 Immunostain, Technical Component Only

Assessment of erythroid lineage

CD4I - Overview: CD4 Immunostain, Technical Component Only

Identification of T helper cells, histiocytes, and monocytes

CD31 - Overview: CD31 Immunostain, Technical Component Only

Marker of endothelial cells

NEUD1 - Overview: Neuronal Differentiation 1 (NeuroD1), Technical Component only

Subclassification of small cell lung carcinoma

TRPS - Overview: Troponin T, 5th Generation, Plasma

Aiding in the exclusion of the diagnosis of acute coronary syndrome in a single plasma specimen Aiding in the diagnosis of acute coronary syndrome Monitoring acute coronary syndromes and estimating prognosis Possible utility in...

CARNU - Overview: Carnitine, Random, Urine

Evaluation of patients with a clinical suspicion of a wide range of conditions including organic acidemias and fatty acid oxidation disorders Monitoring carnitine treatment

CDUCR - Overview: Cadmium/Creatinine Ratio, Random, Urine

Detecting exposure to cadmium, a toxic heavy metal, using random urine specimens

CDKPB - Overview: CD68 (KP1) Immunostain, Bone Marrow, Technical Component Only

Aiding in the identification of histocytic and myeloid lineage cells

FXCH - Overview: Coagulation Factor X Chromogenic Activity Assay, Plasma

Monitoring warfarin anticoagulant therapy, especially in patients whose plasma contains lupus anticoagulants that interfere with baseline prothrombin time/international normalized ratio and in patients receiving the drug Argatroban who are...

CDU - Overview: Cadmium, 24 Hour, Urine

Detecting exposure to cadmium, a toxic heavy metal, in 24-hour urine specimens

CD138 - Overview: CD138 (Syndecan) Immunostain, Technical Component Only

Marker of plasma cells and squamous epithelial cells

CHRO - Overview: Chromogranin Immunostain, Technical Component Only

Aiding in the identification of tumors with neuroendocrine differentiation

F_2 - Overview: Coagulation Factor II Activity Assay, Plasma

Diagnosing a congenital deficiency (rare) of coagulation factor II Evaluating acquired deficiencies associated with liver disease or vitamin K deficiency, oral anticoagulant therapy, and antibody-induced deficiencies (eg, in association...

COXIS - Overview: Coccidioides Antibody Screen with Reflex, Serum

Detecting antibodies to Coccidioides immitis/posadasii This assay should not be used for monitoring response to therapy.

CASF - Overview: IgG/Albumin Ratio, Spinal Fluid

Assessment of cerebrospinal fluid (CSF) IgG/albumin ratio in the absence of a paired CSF and serum specimen

GLUTS - Overview: Glutamine Synthetase Immunostain, Technical Component Only

Classification of hepatic adenomas and the identification of focal nodular hyperplasia

JAKXR - Overview: JAK2 Exon 12-15 Sequencing, Polycythemia Vera Reflex, Varies

Aiding in the distinction between the myeloproliferative neoplasm polycythemia vera (PV) and other secondary erythrocytosis Evaluating for mutations within exons 12 to 15 of JAK2 in an algorithmic process as part of PVJAK / Polycythemia...

C3FX - Overview: C3 Complement, Functional, Serum

Diagnosis of C3 deficiency Investigation of a patient with undetectable total complement level

C5FX - Overview: C5 Complement, Functional, Serum

Diagnosis of C5 deficiency Investigation of a patient with an undetectable total complement level

C8FX - Overview: C8 Complement, Functional, Serum

Diagnosis of C8 deficiency Investigation of a patient with an undetectable total hemolytic complement level

C7FX - Overview: C7 Complement, Functional, Serum

Diagnosis of C7 deficiency Investigation of a patient with an undetectable total complement level

C6FX - Overview: C6 Complement, Functional, Serum

Diagnosis of C6 deficiency Investigation of a patient with an undetectable total complement level

FRAG - Overview: Osmotic Fragility, Erythrocytes

Evaluating suspected hereditary spherocytosis-associated hemolytic anemia Confirming or detecting mild spherocytosis

VHLZZ - Overview: Von Hippel Lindau Syndrome, VHL, Full Gene Analysis, Varies

Evaluating patients with a personal or family history suggestive of Von Hippel-Lindau (VHL) syndrome Establishing a diagnosis of a VHL allowing for targeted cancer surveillance based on associated risks Identifying genetic variants...