10_IS - Overview: Factor X Inhibitor Screen, Plasma

Detecting the presence of a specific factor inhibitor directed against coagulation factor X

F7_IS - Overview: Factor VII Inhibitor Screen, Plasma

Detecting the presence of a specific factor inhibitor directed against coagulation factor VII

F2_IS - Overview: Factor II Inhibitor Screen, Plasma

Detecting the presence of a specific factor inhibitor directed against coagulation factor II

11_IS - Overview: Factor XI Inhibitor Screen, Plasma

Detecting the presence of a specific factor inhibitor directed against coagulation factor XI

IL1B - Overview: Interleukin-1 Beta, Plasma

Measuring the concentration of interleukin-1 beta in plasma Evaluating patients experiencing inflammatory conditions, autoinflammatory disorders, and infection

METR1 - Overview: Cytochrome b5 Reductase Enzyme Activity, Blood

Evaluation of patients with cyanosis Confirming cases of suspected cytochrome b5 reductase (methemoglobin reductase) deficiency Functional studies in families with cytochrome b5 reductase deficiency

COKEU - Overview: Cocaine and Metabolite Confirmation, Random, Urine

Detecting and confirming drug abuse involving cocaine This test is not intended for employment-related testing.

RTSC - Overview: Reptilase Time, Plasma

Evaluation of a prolonged thrombin time (TT): It is mainly used to confirm or exclude the presence of heparin in the specimen or specimen type Evaluating hypofibrinogenemia or dysfibrinogenemia in conjunction with the TT and fibrinogen...

MEPHS - Overview: Mephobarbital and Phenobarbital, Serum

Monitoring of mephobarbital and phenobarbital therapy

THSD7 - Overview: Thrombospondin Type-1 Domain-Containing 7A Antibodies, Serum

Distinguishing primary from secondary membranous nephropathy cases with antibodies against THSD7A

ALBLD - Overview: Bleeding Diathesis Profile, Limited, Plasma

Detection of the more common potential causes of abnormal bleeding (eg, factor deficiencies/hemophilia, von Willebrand disease, factor-specific inhibitors) and a simple screen to evaluate for an inhibitor or severe deficiency of factor XIII...

HCHLG - Overview: Hypercholesterolemia Gene Panel, Varies

Providing a genetic evaluation for patients with a personal or family history suggestive of familial hypercholesterolemia (FH), sitosterolemia, or other monogenic forms of inherited hypercholesterolemia Establishing a diagnosis of FH,...

APROL - Overview: Prolonged Clot Time Profile, Plasma

Determining the cause of prolongation of prothrombin time or activated partial thromboplastin time Screening for prolonged clotting times and determining the presence of factor deficiencies or inhibitor (eg, factor-specific, lupus-like,...

SUPRA - Overview: Supersaturation Profile, Random, Urine

Diagnosis and management of patients with renal lithiasis: -Predicting the likely composition of the stone, in patients who have a radiopaque stone, for whom stone analysis is not available which may help in designing a treatment...

BWRS - Overview: Beckwith-Wiedemann Syndrome/Russell-Silver Syndrome, Molecular Analysis, Varies

Confirming a clinical diagnosis of Beckwith-Wiedemann syndrome (BWS) or Russell-Silver syndrome (RSS) Prenatal diagnosis if there is a high suspicion of BWS/RSS based on ultrasound findings or in families at risk for BWS/RSS This assay...

MPSQU - Overview: Mucopolysaccharides Quantitative, Random, Urine

Supporting the biochemical diagnosis of one of the mucopolysaccharidoses: types I, II, III, IV, VI, or VII

IDTRT - Overview: IDH1, IDH2, and TERT Mutation Analysis, Next-Generation Sequencing, Tumor

Identifying specific mutations within the IDH1 and IDH2 genes and the TERT promoter to assist in tumor diagnosis/classification

XL2T - Overview: FOXL2 Mutation Analysis, Next-Generation Sequencing, Tumor

Assisting in the clinical diagnosis of adult granulosa cell tumor by assessing gene targets with in the FOXL2 gene

AMA - Overview: Mitochondrial Antibodies (M2), Serum

Establishing the diagnosis of primary biliary cholangitis This test is not useful for indicating the stage or prognosis of the disease or for monitoring the course of the disease.

AACSF - Overview: Amino Acids, Quantitative, Spinal Fluid

Evaluating patients with possible inborn errors of amino acid metabolism, particularly nonketotic hyperglycinemia (glycine encephalopathy) and serine biosynthesis defects, especially when used in conjunction with concomitantly collected...

BRAZR - Overview: Brazil Nut, IgE with Reflex to Brazil Nut Component, IgE, Serum

Evaluation of patients with suspected Brazil nut allergy

MCMRU - Overview: Mast Cell Mediators, Random, Urine

Evaluating patients at risk for mast cell activation syndrome (eg, systemic mastocytosis) using random urine collections

COMTQ - Overview: Catechol-O-Methyltransferase (COMT) Genotype, Varies

Prediction of response to nicotine replacement therapy for smoking cessation Investigation of inhibitor dosing for decreasing levodopa metabolism Research use for assessing estrogen metabolism

PFKC - Overview: Phosphofructokinase Enzyme Activity, Blood

Evaluation of individuals with Coombs-negative nonspherocytic hemolytic anemia Evaluation of individuals with exercise intolerance or myopathy Genetic studies in families with phosphofructokinase deficiency

PHOS - Overview: Phosphorus (Inorganic), Serum

Diagnosis and management of a variety of disorders including bone, parathyroid, and kidney disease

VALPA - Overview: Valproic Acid, Total, Serum

Monitoring total valproic acid in therapy Assessing compliance Evaluating potential toxicity

CDCU - Overview: Cadmium/Creatinine Ratio, Urine

Detecting exposure to cadmium using random urine specimens

T46CC - Overview: Tripartite Motif-Containing Protein 46 (TRIM46) IgG, Cell Binding Assay, Spinal Fluid

Detecting tripartite motif-containing protein 46 (TRIM46)-IgG by cell-binding assay using cerebrospinal fluid specimens Evaluation of an autoimmune/paraneoplastic neurological syndrome among patients presenting with cerebellar ataxia,...

T46IS - Overview: Tripartite Motif-Containing Protein 46 (TRIM46) IgG, Tissue Immunofluorescence, Serum

Detecting tripartite motif-containing protein 46 (TRIM46)-IgG in serum specimens Evaluation of an autoimmune/paraneoplastic neurological syndrome among patients presenting with cerebellar ataxia, encephalitis, or encephalomyelitis

T46IC - Overview: Tripartite Motif-Containing Protein 46 (TRIM46) IgG, Tissue Immunofluorescence, Spinal Fluid

Detecting tripartite motif-containing protein 46 (TRIM46)-IgG in cerebrospinal fluid specimens Evaluation of an autoimmune/paraneoplastic neurological syndrome among patients presenting with cerebellar ataxia, encephalitis, or...

T46TS - Overview: Tripartite Motif-Containing Protein 46 (TRIM46) IgG, Tissue Immunofluorescence Titer, Serum

Reporting an end titer result for tripartite motif-containing protein 46 (TRIM46)-IgG in serum specimens Evaluation of an autoimmune/paraneoplastic neurological syndrome among patients presenting with cerebellar ataxia, encephalitis, or...

T46TC - Overview: Tripartite Motif-Containing Protein 46 (TRIM46) IgG, Tissue Immunofluorescence Titer, Spinal Fluid

Reporting an end-titer result for tripartite motif-containing protein 46 (TRIM46)-IgG in cerebrospinal fluid specimens Evaluation of an autoimmune/paraneoplastic neurological syndrome among patients presenting with cerebellar ataxia,...

ALPRT - Overview: Alport (Collagen IV Alpha 5 and Alpha 2) Immunofluorescent Stain, Renal Biopsy

Assisting in the diagnosis of hereditary nephritis (Alport syndrome)

FIBTP - Overview: Fibrinogen, Plasma

Detecting increased or decreased fibrinogen (factor I) concentration of acquired or congenital origin Monitoring severity and treatment of disseminated intravascular coagulation and fibrinolysis

GBETH - Overview: General Factor Bethesda Units, Plasma

Detecting and quantifying the presence and titer of a specific factor inhibitor directed against a specific coagulation factor

F5_IS - Overview: Factor V Inhibitor Screen, Plasma

Detecting the presence of a specific factor inhibitor directed against coagulation factor V

AMTRP - Overview: Amitriptyline and Nortriptyline, Serum

Monitoring amitriptyline and nortriptyline serum concentrations during therapy Evaluating potential amitriptyline and nortriptyline toxicity May aid in evaluating patient compliance

A2PI - Overview: Alpha-2 Plasmin Inhibitor, Plasma

Diagnosing congenital alpha-2 plasmin inhibitor deficiencies (rare) Providing a complete assessment of disseminated intravascular coagulation, intravascular coagulation and fibrinolysis, or hyperfibrinolysis (primary fibrinolysis), when...

F_9 - Overview: Coagulation Factor IX Activity Assay, Plasma

Diagnosing deficiencies, particularly hemophilia B (Christmas disease) Assessing the impact of liver disease on hemostasis Investigation of a prolonged activated partial thromboplastin time

SFINC - Overview: Cerebrospinal Fluid (CSF) IgG Index, Spinal Fluid

Aiding in the diagnosis of multiple sclerosis and other central nervous system inflammatory conditions using cerebrospinal fluid specimens

NARC - Overview: Narcolepsy-Associated Antigen, HLA-DQB1 Typing, Blood

Ruling out a diagnosis of narcolepsy

SFZ - Overview: Sulfamethoxazole, Serum

Monitoring sulfamethoxazole therapy to ensure drug absorption, clearance, or compliance

CNSA - Overview: Central Nervous System Consultation, Autopsy, Varies

Evaluation of congenital neurological disease Evaluation of neurodegenerative disease Evaluation of cases with a complex neurological or neurosurgical history Evaluation of sudden unexplained death This test is not intended for...

CDOU - Overview: Cadmium Occupational Exposure, Random, Urine

Detecting occupational exposure to cadmium using random urine specimens

F9_IS - Overview: Factor IX Inhibitor Screen, Plasma

Detecting the presence of a specific factor inhibitor directed against coagulation factor IX

PNPAB - Overview: Paraneoplastic Pemphigus Antibody, IgG, Serum

Diagnosis of paraneoplastic pemphigus/paraneoplastic autoimmune multiorgan syndrome in the setting of erosive or lichenoid mucocutaneous disease

CALX - Overview: CALR Mutation Analysis, Myeloproliferative Neoplasm (MPN), Reflex, Varies

Aiding in the distinction between a reactive cytosis and a chronic myeloproliferative disorder Evaluating mutations in CALR in an algorithmic process for the MPNR / Myeloproliferative Neoplasm, JAK2 V617F with Reflex to CALR and MPL,...

T46CS - Overview: Tripartite Motif-Containing Protein 46 (TRIM46) IgG, Cell Binding Assay, Serum

Detecting tripartite motif-containing protein 46 (TRIM46)-IgG by cell-binding assay using serum specimens Evaluation of an autoimmune/paraneoplastic neurological syndrome among patients presenting with cerebellar ataxia, encephalitis, or...

F_10 - Overview: Coagulation Factor X Activity Assay, Plasma

Diagnosing deficiency of coagulation factor X, congenital or acquired Evaluating hemostatic function in liver disease Investigation of prolonged prothrombin time or activated partial thromboplastin time

MET - Overview: Methemoglobin and Sulfhemoglobin, Blood

Diagnosing methemoglobinemia and sulfhemoglobinemia Identifying cyanosis due to other causes, such as congenital heart disease