IDHT - Overview: IDH1 and IDH2 Mutation Analyses, Next-Generation Sequencing, Tumor

Identifying specific mutations within the IDH1 and IDH2 genes that assist in tumor diagnosis/classification and predict response to targeted therapy

WAGDR - Overview: Alpha Globin Cluster Locus Deletion/Duplication, Blood

Diagnosis of alpha-thalassemia Carrier screening for individuals from high-risk populations for alpha-thalassemia This test is not useful for diagnosis or confirmation of beta-thalassemia or hemoglobinopathies.

CRCOF - Overview: Chromium and Cobalt, Synovial Fluid

Monitoring metallic prosthetic implant wear and local tissue destruction in failed hip arthroplasty constructs This test is not useful for assessment of vitamin B12 activity.

HVA - Overview: Homovanillic Acid, 24 Hour, Urine

Screening children for catecholamine-secreting tumors using a 24-hour urine collection when requesting homovanillic acid only Monitoring neuroblastoma treatment Screening patients with possible inborn errors of catecholamine metabolism

RO52 - Overview: Ro52 Antibody, IgG, Serum

Evaluating patients at risk for connective tissue disease with or without interstitial lung disease Differentiating single vs double positivity for Ro52 and Ro60 antibodies in combination with anti-Ro60

RO60 - Overview: Ro60 Antibody, IgG, Serum

Evaluating patients at risk for connective tissue disease with or without interstitial lung disease Differentiating single vs double positivity for Ro52 and Ro60 antibodies in combination with anti-Ro60

ROPAN - Overview: Ro52 and Ro60 Antibodies, IgG, Serum

Evaluating patients at risk for connective tissue disease with or without interstitial lung disease Differentiation of antibodies to Ro52 and Ro60 in patients known to be positive for anti-SS-A (Ro) antibodies

DNSAG - Overview: Dengue Virus NS1 Antigen, Serum

Aiding in the diagnosis of dengue virus infection

CRANR - Overview: Cortisol, Free, Random, Urine

Investigating suspected hypercortisolism when a 24-hour collection is prohibitive (ie, pediatric patients)

CHF8 - Overview: Chromogenic Factor VIII Activity Assay, Plasma

Monitoring coagulation factor replacement therapy of selected extended half-life coagulation factor replacements Aiding in the diagnosis of hemophilia A using a 2-stage assay, especially when the 1-stage assay result was normal

CHIKC - Overview: Chikungunya Virus, PCR, Molecular Detection, Spinal Fluid

Qualitative detection of chikungunya virus in cerebrospinal fluid after early symptom onset (ideally <7 days) This test is not recommended for screening healthy patients.

11INE - Overview: Factor XI Inhibitor Evaluation, Plasma

Detection and quantitation of inhibitor to coagulation factor XI This test is not useful for the detection of a lupus-like circulating anticoagulant inhibitor, a nonspecific circulating anticoagulant, or other inhibitors that are not...

5INHE - Overview: Factor V Inhibitor Evaluation, Plasma

Detection and quantitation of inhibitors against coagulation factor V This test is not useful for the detection of a lupus-like circulating anticoagulant inhibitor, a nonspecific circulating anticoagulant, or other inhibitors that are not...

10INE - Overview: Factor X Inhibitor Evaluation, Plasma

Detection and quantitation of inhibitor to coagulation factor X This test is not useful for the detection of a lupus-like circulating anticoagulant inhibitor, a nonspecific circulating anticoagulant, or other inhibitors that are not...

FRTUP - Overview: Free Thyroxine Index (FTI), Serum

Estimating the amount of circulating free thyroxine (free thyroxine index) using the total thyroxine and thyroid binding capacity (T-uptake)

FACT - Overview: Filamentous-Actin (F-actin) Antibody, IgG, Serum

Evaluation of patients with hepatitis of unknown origin associated with hypergammaglobulinemia and/or abnormal liver enzymes This test may also be useful for confirming positivity for smooth muscle antibodies.

LAD1 - Overview: Leukocyte Adhesion Deficiency Type 1, CD11a/CD18 and CD11b/CD18 Complex Immunophenotyping, Blood

Aiding in the diagnosis of leukocyte adhesion deficiency syndrome type 1, primarily in patients younger than 18 years CD11a, CD11b, and CD18 phenotyping

TOXGP - Overview: Toxoplasma gondii Antibody, IgG, Serum

Determining whether a patient has had previous exposure to or recent infection with Toxoplasma gondii This test is not useful for diagnosing infection in infants younger than 6 months of age. In that age group, IgG antibodies usually are...

VH - Overview: Vanillylmandelic Acid and Homovanillic Acid, Random, Urine

Preferred first test for screening for catecholamine-secreting tumors in a random urine specimen when requesting both homovanillic acid and vanillylmandelic acid Supporting a diagnosis of neuroblastoma Monitoring patients with a treated...

VMA - Overview: Vanillylmandelic Acid, 24 Hour, Urine

Screening children for catecholamine-secreting tumors using a 24-hour urine collection when requesting testing for vanillylmandelic acid only Supporting a diagnosis of neuroblastoma Monitoring patients with a treated neuroblastoma

MATCC - Overview: Maternal Cell Contamination, Molecular Analysis, Varies

Ruling out the presence of maternal cell contamination within a fetal specimen Required for all prenatal testing performed in Mayo Clinic Laboratories' Molecular and Biochemical Genetics laboratories

PTTP - Overview: Prothrombin Time, Plasma

Screening assay to detect deficiencies of one or more coagulation factors (factors I, II, V, VII, X) Screening assay to detect coagulation inhibition Monitoring intensity of oral anticoagulant therapy when combined with INR reporting

2INHE - Overview: Factor II Inhibitor Evaluation, Plasma

Detection and quantitation of inhibitor to factor II This test is not useful for the detection of a lupus-like circulating anticoagulant inhibitor, a nonspecific circulating anticoagulant, or other inhibitors that are not specific for...

BRIVA - Overview: Brivaracetam, Plasma

Assessing compliance and toxicity for brivaracetam

FHLCG - Overview: Immunoglobulin G (IgG) Heavy and Light Chain (HLC) Pairs, Kappa and Lambda with Ratio

Heavy and light chain pair quantitation may be useful for: 1. Distinguishing between broadly migrating monoclonal proteins and restricted polyclonal immunoglobulin patterns on serum electrophoresis. 2. Quantitating monoclonal IgG proteins...

NOTRP - Overview: Nortriptyline, Serum

Monitoring nortriptyline concentration during therapy Evaluating potential nortriptyline toxicity May aid in evaluating patient compliance

FELBA - Overview: Felbamate (Felbatol), Serum

Determining whether a poor therapeutic response is attributable to noncompliance or lack of drug effectiveness Monitoring changes in serum concentrations resulting from interactions with coadministered drugs such as barbiturates and...

LD - Overview: Lactate Dehydrogenase (LDH), Serum

Investigation of a variety of diseases involving the heart, liver, muscle, kidney, lung, and blood Monitoring changes in tumor burden after chemotherapy; lactate dehydrogenase elevations in patients with cancer are too erratic to be of use...

TOPI - Overview: Topiramate, Serum

Monitoring serum concentrations of topiramate Assessing compliance Assessing potential toxicity

MSTC - Overview: Strict Criteria Sperm Morphology for Infertility Diagnosis and Treatment, Semen

Diagnosing male infertility Selecting the most cost-effective therapy for treating male-factor infertility Quantifying the number of germinal and white blood cells per mL of semen

VITB2 - Overview: Riboflavin (Vitamin B2), Plasma

Evaluation of individuals who present the signs of ariboflavinosis

FBENZ - Overview: Benztropine (Cogentin), Serum

Benztropine (Cogentin), Serum

FIL4S - Overview: Interleukin-4 (IL-4) Serum

Interleukin-4 (IL-4) Serum

ZW334 - Overview: Miscellaneous Variantyx, Inc.

Miscellaneous Variantyx, Inc.

FFTIN - Overview: Tin, Serum

Tin, Serum

HBVQN - Overview: Hepatitis B Virus (HBV) DNA Detection and Quantification by Real-Time PCR, Serum

Detection and quantification of hepatitis B virus (HBV) DNA in serum of patients with chronic HBV infection (ie, hepatitis B surface antigen-positive) Monitoring disease progression in chronic HBV infection Monitoring response to anti-HBV...

NSE - Overview: Neuron-Specific Enolase, Serum

A follow-up marker in patients with neuron-specific enolase-secreting tumors of any type An auxiliary test in the diagnosis of small cell lung carcinoma An auxiliary test in the diagnosis of carcinoids, islet cell tumors, and...

8INHE - Overview: Factor VIII Inhibitor Evaluation, Plasma

Detecting the presence and titer of a specific factor inhibitor directed against coagulation factor VIII This test is not useful for the detection of a lupus-like circulating anticoagulant inhibitor, a nonspecific circulating...

LIVPR - Overview: Liver Profile, Serum

Screening for liver damage, especially if someone has a condition or is taking a drug that may affect the liver

TMSI - Overview: Microsatellite Instability, Tumor

Evaluation of tumor tissue to identify patients at high risk for having Lynch syndrome, also known as hereditary nonpolyposis colorectal cancer Evaluation of tumor tissue for clinical decision-making purposes given the prognostic and...

SP100 - Overview: SP100 Antibody, IgG, Serum

Evaluating the risk of primary biliary cholangitis in anti-mitochondrial antibody (AMA) negative patients by identification of Sp100 antibodies Estimating risk in AMA-positive patients with incomplete feature of disease

17OHP - Overview: 17-Hydroxypregnenolone, Serum

As an ancillary test for congenital adrenal hyperplasia (CAH), particularly in situations in which a diagnosis of both 21- and 11-hydroxylase deficiency have been ruled out Confirming a diagnosis of 3-beta-hydroxysteroid dehydrogenase...

EGFRS - Overview: EGFR Gene, Targeted Mutation Analysis, 51 Mutation Panel, Tumor

Identifying non-small cell lung cancers that may respond to epidermal growth factor receptor-targeted therapies

IL28Q - Overview: Interleukin 28B (IL28B) Variant (rs12979860), Varies

Predicting responsiveness of genotype 1 hepatitis C viral infections to combined pegylated-interferon and ribavirin-based therapies

BMAMA - Overview: Basic Metabolic Panel, Serum

Routine health monitoring or patient monitoring while hospitalized for information regarding metabolism, including the current kidney status, electrolyte, and acid/base balance, and blood glucose

MPQU - Overview: Monoclonal Protein Quantitation, 24 Hour, Urine

Monitoring patients with monoclonal gammopathies using 24-hour urine collections

ENDCP - Overview: Hereditary Endocrine Cancer Panel, Varies

Evaluating patients with a personal or family history suggestive of a hereditary endocrine tumor syndrome Establishing a diagnosis of a hereditary endocrine tumor syndrome, allowing for targeted surveillance based on associated risks...

FHLAA - Overview: HLA A High Resolution

HLA A High Resolution

FHTL - Overview: HTLV I/II DNA, Qualitative Real-Time PCR

HTLV I/II DNA, Qualitative Real-Time PCR

FIFNY - Overview: Interferon-gamma (IFN-y) Serum

Interferon-gamma (IFN-y) Serum