MFRGG - Overview: Marfan, Loeys-Dietz, and Aortopathy Gene Panel, Varies
Providing a genetic evaluation for patients with a personal or family history suggestive of Marfan syndrome and related conditions Establishing a diagnosis for Marfan syndrome, Loeys-Dietz syndrome, vascular Ehlers-Danlos syndrome,...
CACMG - Overview: Comprehensive Arrhythmia and Cardiomyopathy Gene Panel, Varies
Providing a genetic evaluation for patients with a personal or family history suggestive of a hereditary form of either a cardiomyopathy or cardiac arrhythmia Establishing a diagnosis of a hereditary form of either a cardiomyopathy or...
Providing a genetic evaluation for patients with a personal or family history suggestive of recessive congenital methemoglobinemia Genotype confirmation of borderline cytochrome b5 reductase (methemoglobin reductase: METR) enzyme activity...
FLARP - Overview: Free-Living Amebae, Molecular Detection, PCR, Varies
Aids in the diagnosis of primary amebic meningoencephalitis and granulomatous amebic encephalitis in spinal fluid and tissue in conjunction with clinical and radiologic findings This test should not be used to screen asymptomatic patients.
Diagnostic workup of patients with high probability of BCR::ABL1-positive hematopoietic neoplasms, predominantly chronic myeloid/myelogenous leukemia and acute lymphoblastic leukemia
Rapid identification to the species level and susceptibility testing for Mycobacterium species, Nocardia species, and other aerobic actinomycete genera and species from pure culture isolates
ROMA2 - Overview: Risk Score, if Postmenopausal, Serum
Calculating risk assessment for finding an ovarian malignancy during surgery in postmenopausal women who present with an adnexal mass
FGHRH - Overview: Growth Hormone Releasing Hormone (GH-RH, also known as GHRF or GRF)
Growth Hormone Releasing Hormone (GH-RH, also known as GHRF or GRF)
A1R - Overview: A1 Antigen Subtype, Blood
Additional proof of alloantibody specificity Assessment of solid organ transplantation donor compatibility This test is not useful for the purpose of establishing paternity.
FANG1 - Overview: Angiotensin I, Plasma
Angiotensin I, Plasma
BOAC - Overview: Boron, Serum/Plasma
Boron, Serum/Plasma
FSERO - Overview: SeroNeg RAdx3 Profile
SeroNeg RAdx3 Profile
PHD2 - Overview: Prolyl Hydroxylase Domain-2 (PHD2/EGLN1) Gene Sequencing, Whole Blood
Assessing PHD2/EGLN1 in the evaluation of an individual with JAK2-negative erythrocytosis associated with lifelong sustained increased red blood cell (RBC) mass, elevated RBC count, hemoglobin, or hematocrit
TOXGP - Overview: Toxoplasma gondii Antibody, IgG, Serum
Determining whether a patient has had previous exposure to or recent infection with Toxoplasma gondii This test is not useful for diagnosing infection in infants younger than 6 months of age. In that age group, IgG antibodies usually are...
HBA1C - Overview: Hemoglobin A1c, Blood
Evaluating the long-term control of blood glucose concentrations in patients with diabetes Diagnosing diabetes Identifying patients at increased risk for diabetes (prediabetes) This assay is not useful in determining day-to-day glucose...
MYCO - Overview: Mycoplasma pneumoniae Antibodies, IgG and IgM, Serum
Screening for recent or past exposure to Mycoplasma pneumoniae This test should not be used as a screening procedure for the general population.
NMHR - Overview: N-Methylhistamine, Random, Urine
Screening for and monitoring of mastocytosis and disorders of systemic mast-cell activation, such as anaphylaxis and other forms of severe systemic allergic reactions using random urine specimens Monitoring therapeutic progress in...
Assessing HIF2A/EPAS1 in the evaluation of an individual with JAK2-negative erythrocytosis associated with lifelong sustained increased red blood cell (RBC) mass, elevated RBC count, hemoglobin, or hematocrit
BAIPD - Overview: Bile Acids for Peroxisomal Disorders, Serum
Biomarker for peroxisomal biogenesis disorders, such as Zellweger spectrum disorder and single enzyme defects of bile acid synthesis, including D-bifunctional protein deficiency and alpha methyl CoA racemases Monitoring patients receiving...
OPATX - Overview: Opiates Confirmation, Chain of Custody, Random, Urine
Detection and quantification of codeine, hydrocodone, oxycodone, morphine, hydromorphone, oxymorphone, noroxycodone, noroxymorphone, norhydrocodone, dihydrocodeine, and naloxone in urine Chain of custody is required whenever the results of...
P504S - Overview: P504S Immunostain, Technical Component Only
Characterization of renal cell carcinoma and the identification of high-grade prostatic intraepithelial neoplasia and prostate carcinoma
WNGS - Overview: West Nile Virus Antibody, IgG, Serum
Detection of IgG antibodies in West Nile virus infections
VEGF - Overview: Vascular Endothelial Growth Factor, Plasma
Evaluation of patients with suspected POEMS (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes) syndrome, particularly in differentiating from other forms of polyneuropathy and/or monoclonal plasma cell...
VITB3 - Overview: Vitamin B3 and Metabolites, Plasma
Assisting in the diagnosis of suspected vitamin B3 deficiency or toxicity May be useful in determining response to therapy
APHTC - Overview: Amphiphysin Antibody Titer Assay, Spinal Fluid
Evaluating patients with recent onset of a subacute neurological disorder for which a paraneoplastic basis might be suspected, particularly if the patient has a previous history, risk factors, or family history of cancer, especially lung or...
RHUT - Overview: Rheumatoid Factor, Serum
Diagnosis and prognosis of rheumatoid arthritis
PRAME - Overview: PRAME Immunostain, Technical Component Only
Differentiation between melanoma and benign nevi.
CIFA - Overview: Cutaneous Immunofluorescence Antibodies, IgA, Serum
Confirming the presence of IgA antibodies to diagnose pemphigoid, pemphigus, epidermolysis bullosa acquisita, or bullous lupus erythematosus
MHPRP - Overview: Metamycoplasma hominis, Molecular Detection, PCR, Plasma
Rapid, sensitive, and specific identification of Metamycoplasma hominis from plasma This test is not intended for medicolegal use.
Detecting zinc deficiency
THCG - Overview: Human Chorionic Gonadotropin (hCG), Quantitative, Pregnancy, Serum
Early detection of pregnancy Investigation of suspected ectopic pregnancy or other pregnancy-related complications Monitoring in vitro fertilization patients This test is not useful for detecting or monitoring tumors or gestational...
HMGA - Overview: High Mobility Group A2 (HMGA2) Immunostain, Technical Component Only
Identification of abnormal expression of the high mobility group protein, HMGA2
LGBWB - Overview: Globotriaosylsphingosine, Blood
Screening of patients with Fabry disease when a serum specimen is not available This test should not be used for newborn screening followup.
HCQ - Overview: Hydroxychloroquine, Serum
Monitoring serum hydroxychloroquine concentrations, assessing compliance, and adjusting dosage in patients
FENR - Overview: Fentanyl Screen with Reflex, Random, Urine
Screening for drug abuse or use involving fentanyl and confirmation of fentanyl if present in the screen
UE3 - Overview: Estriol, Unconjugated, Serum
As an adjunct biomarker in the prenatal diagnosis of disorders of fetal steroid metabolism, including Smith-Lemli-Opitz syndrome (1,2) and X-linked ichthyosis (placental sulfatase deficiency disorders) Evaluating primary or secondary fetal...
KRT34 - Overview: Keratin (34BE12) Immunostain, Technical Component Only
Identification of cells expressing high-molecular-weight cytokeratin
WASQR - Overview: Alpha-Globin Gene Sequencing, Blood
Testing for nondeletional alpha thalassemia in a symptomatic individual Follow-up testing to an abnormal hemoglobin electrophoresis that identified an alpha-globin chain variant Evaluating for nondeletional alpha thalassemias in an...
ASO - Overview: Antistrep-O Titer, Serum
Demonstration of acute or recent streptococcal infection
MSUSC - Overview: Branched-Chain Amino Acids, Self-Collect, Blood Spot
Monitoring patients with maple syrup urine disease using specimens collected at home
CD200 - Overview: CD200 (OX2) Immunostain, Technical Component Only
Identifying the presence of CD200 (OX2) protein within chronic lymphocytic leukemia, small lymphocytic lymphoma, hairy cell leukemia, and primary mediastinal large B-cell lymphoma
MT - Overview: Metallothionein Immunostain, Technical Component Only
Supporting the diagnosis of Wilson disease
PNYA - Overview: Phenytoin, Total, Serum
Monitoring for appropriate therapeutic concentration Assessing compliance or toxicity
MEF2B - Overview: Myocyte Enhancer Factor 2 (MEF2B) Immunostain, Technical Component Only
Lymphoma classification
SABP - Overview: Streptococcal Antibodies Profile, Serum
Demonstration of acute or recent streptococcal infection using both antistreptolysin O and anti-DNase B titers
PIK3B - Overview: Cell-Free DNA PIK3CA Test, Blood
Identification of hormone receptor positive and human epidermal growth factor receptor 2 negative (HR+/HER2-) advanced breast cancer tumors that may be eligible for treatment with targeted kinase inhibitor therapy (eg, alpelisib).
ULFA - Overview: Cryptococcus Antigen Screen, Lateral Flow Assay, Random, Urine
Aiding in the diagnosis of infection with Cryptococcus neoformans or Cryptococcus gattii This test should not be used as a test of cure. This test should not be used as a screening procedure for the general population.
C1ES - Overview: C1 Esterase Inhibitor Antigen, Serum
Diagnosis of hereditary angioedema Monitoring levels of C1 esterase inhibitor in response to therapy
SGSU - Overview: Synthetic Glucocorticoid Screen, Random, Urine
Confirming the presence of the listed synthetic glucocorticoids Confirming the cause of secondary adrenal insufficiency
APHTS - Overview: Amphiphysin Antibody Titer Assay, Serum
Evaluating patients with recent onset of a subacute neurological disorder for which a paraneoplastic basis might be suspected, particularly if the patient has a previous history, risk factors, or family history of cancer, especially lung or...
Mayo Clinic Ranked No. 1 Hospital Nationwide by U.S. News & World Report - Insights
Report’s 29th annual "Best Hospitals Honor Roll" published online on August 14. Mayo Clinic also ranked No. 1 in more specialties than any other hospital in the country....
NELL-1 [Test in Focus] - Insights
D., discusses how Mayo Clinic Laboratories’ new immunohistochemistry test for the detection of NELL-1 antigen, a biomarker for membranous nephropathy found in 10% to 15% of patients, provides diagnostic...
Looking Back on Clinical Chemistry 1 - Insights
in the Mayo Clinic Medical Laboratory Science program, takes a look back on her Clinical Chemistry 1 course....
Orexin-A/Hypocretin-1 for the Diagnosis of Type 1 Narcolepsy [Test in Focus] - Insights
test to perform as well as to interpret. The orexin-A/hypocretin-1 test is a sensitive and specific alternative to the MSLT to diagnose type 1 narcolepsy....
Week in Review: November 1 - Insights
Top highlights include: Facebook launches into the digital space of healthcare, medical breakthrough for Ebola, and how the brain makes memories.