PIK3T - Overview: PIK3CA Mutation Analysis, Tumor

Identification of hormone receptor positive and human epidermal growth factor receptor 2 negative (HR+/HER2-) advanced breast cancer tumors that may be eligible for treatment with targeted kinase inhibitor therapy (eg, alpelisib).

HVAR - Overview: Homovanillic Acid, Random, Urine

Screening children for catecholamine-secreting tumors using a random urine collection when requesting homovanillic acid only Monitoring neuroblastoma treatment Screening patients with possible inborn errors of catecholamine metabolism

ROXUR - Overview: Oxalate, Random, Urine

Monitoring therapy for kidney stones using random urine specimens Identifying increased urinary oxalate as a risk factor for stone formation Diagnosis of primary or secondary hyperoxaluria

HERGM - Overview: HER2, Gastric/Esophageal, Semi-Quantitative Immunohistochemistry, Manual

Determining overexpression of HER2 protein of gastric and esophageal adenocarcinoma in formalin-fixed, paraffin-embedded tissue sections (with reflex to FISH testing)

AFPA - Overview: Alpha-Fetoprotein, Amniotic Fluid

Screening for open neural tube defects or other fetal abnormalities Follow-up testing for patients with elevated serum alpha-fetoprotein results or in conjunction with cytogenetic testing

TDP - Overview: Thiamine (Vitamin B1), Whole Blood

Assessment of thiamine deficiency Measuring thiamine levels in patients with behavioral changes, eye signs, gait disturbances, delirium, and encephalopathy; or in patients with questionable nutritional status, especially those who appear...

COKMX - Overview: Cocaine and Metabolite Confirmation, Chain of Custody, Meconium

Detecting in utero drug exposure up to 5 months before birth Chain of custody is required whenever the results of testing could be used in a court of law. Its purpose is to protect the rights of the individual contributing the specimen by...

CDUOE - Overview: Cadmium Occupational Exposure, Random, Urine

Detecting occupational exposure to cadmium, a toxic heavy metal, using random urine specimens

PRCAL - Overview: Procalcitonin, Serum

Monitoring antibiotic therapy and all-cause mortality for patients diagnosed with severe sepsis or septic shock in the Intensive Care Unit (ICU) or when obtained in the emergency department or other medical wards prior to ICU admission

LCMS - Overview: Leukemia/Lymphoma Immunophenotyping, Flow Cytometry, Varies

Evaluating lymphocytoses of undetermined etiology Identifying B- and T-cell lymphoproliferative disorders involving blood and bone marrow Distinguishing acute lymphoblastic leukemia (ALL) from acute myeloid leukemia (AML) Immunologic...