MPLR - Overview: MPL Exon 10 Mutation Detection, Reflex, Varies

Aiding in the distinction between a reactive cytosis and a chronic myeloproliferative disorder Evaluates for mutations in MPL in an algorithmic process for the MPNR / Myeloproliferative Neoplasm, JAK2 V617F with Reflex to CALR and MPL,...

RT3 - Overview: T3 (Triiodothyronine), Reverse, Serum

Aiding in the diagnosis of the sick euthyroid syndrome

SOLFM - Overview: Soluble Fibrin Monomer, Plasma

Assisting in the diagnosis of arterial or venous prethrombotic states in various pathological and clinical situations including disseminated intravascular coagulation/intravascular coagulation and fibrinolysis and postoperative monitoring...

NECT4 - Overview: Nectin-4, Semi-Quantitative Immunohistochemistry, Manual

Identifying nectin-4 overexpression in bladder cancer and other cancers

Algorithms - Mayo Clinic Laboratories

Test Catalog AlgorithmsDownload Test Catalog & Interpretive HandbookNew TestsNY State Informed Consent TestsPerforming LocationsReferred TestsSpecialty TestingTest Updates...

URCON - Overview: Urea, Random, Urine

Assessment of kidney failure (prerenal vs acute kidney injury)

RPHOC - Overview: Phosphorus, Random, Urine

Evaluation of hypo- or hyperphosphatemic states Evaluation of patients with nephrolithiasis

COL7 - Overview: Anti-Collagen type VII, IgG Antibodies, Serum

Initial screening test in the diagnosis of epidermolysis bullosa acquisita and other immunobullous diseases mediated by collagen VII

RPDEI - Overview: Rapidly Progressive Dementia Evaluation Interpretation, Spinal Fluid

Interpretation of the Rapidly Progressive Dementia Evaluation

SER - Overview: Serotonin, Serum

In conjunction with, or as an alternative to, first-order tests in the differential diagnosis of isolated symptoms suggestive of carcinoid syndrome, in particular flushing (5-hydroxyindoleacetic acid or serum chromogranin A measurements are...

MMLSA - Overview: Antimicrobial Susceptibility, Anaerobic Bacteria, Minimal Inhibitory Concentration, Varies

Determining the in vitro susceptibility on isolates of anaerobic bacteria involved in human infections Directing antimicrobial therapy for anaerobic bacterial infections

ABYSR - Overview: Antibody Screen with Reflexed Antibody Identification, Blood

Detection of allo- or autoantibodies directed against red blood cell antigens in the settings of pretransfusion testing Evaluation of transfusion reactions Evaluation of hemolytic anemia

APBCC - Overview: Adaptor Protein 3 Beta2 (AP3B2) Antibody, Cell-Binding Assay, Spinal Fluid

The differential diagnosis of patients presenting with mixed cerebellar and sensory ataxia and myeloneuropathy Evaluating AP3B2 (adaptor protein 3 beta2)-IgG by cell-binding assay using spinal fluid specimens

APBCS - Overview: Adaptor Protein 3 Beta2 (AP3B2) Antibody, Cell-Binding Assay, Serum

The differential diagnosis of patients presenting with mixed cerebellar and sensory ataxia and myeloneuropathy Evaluating AP3B2 (adaptor protein 3 beta2)-IgG by cell-binding assay using serum specimens

RCTUR - Overview: Creatinine, Random, Urine

Calculation of creatinine clearance, a measure of renal function, when used in conjunction with serum creatinine Normalization of urinary analytes by creatinine concentration to account for the variation in urinary concentrations between...

METR1 - Overview: Cytochrome b5 Reductase Enzyme Activity, Blood

Evaluation of patients with cyanosis Confirming cases of suspected cytochrome b5 reductase (methemoglobin reductase) deficiency Functional studies in families with cytochrome b5 reductase deficiency

HPVE6 - Overview: Human Papillomavirus (HPV) High-Risk E6/E7, RNA In Situ Hybridization

Stratification of oropharyngeal squamous cell carcinoma

HPVHL - Overview: Human Papillomavirus (HPV) High/Low Risk, In Situ Hybridization

Detecting human papillomavirus for both low-risk (6, 11) and high-risk (16, 18, 26, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66, 68, 73, and 82.) genotypes

CRT2F - Overview: Creatinine, 24 Hour, Urine

Normalizing urinary analytes to account for the variation in urinary concentration

F8IS - Overview: Coagulation Factor VIII Inhibitor Screen, Plasma

Detecting the presence of a specific factor inhibitor directed against coagulation factor VIII

CHCK - Overview: Chicken Feathers, IgE, Serum

Establishing a diagnosis of an allergy to chicken feathers Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or anaphylactic episode -To confirm...

HICSF - Overview: Histoplasma Antibody Complement Fixation and Immunodiffusion, Spinal Fluid

Aiding in the diagnosis of Histoplasma meningitis using spinal fluid specimens

NEGCT - Overview: Negative Control, Technical Component Only

Qualitative detection of protein expression within cells in paraffin-embedded tissues

POU - Overview: Phosphorus, 24 Hour, Urine

Evaluation of hypo- or hyper-phosphatemic states Evaluation of patients with nephrolithiasis

PEAR - Overview: Pear, IgE, Serum

Establishing a diagnosis of an allergy to pear Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or anaphylactic episode -To confirm sensitization prior to...

PARVN - Overview: Parvovirus B19 Antibody, Technical Interpretation

Interpretation of serologic testing for recent or past parvovirus B19 infection This test is not useful as a screening procedure for the general population

PRCON - Overview: Protein, Total, Random, Urine

Measurement of total protein for the assessment of orthostatic proteinuria

RTSC - Overview: Reptilase Time, Plasma

Evaluation of a prolonged thrombin time (TT): It is mainly used to confirm or exclude the presence of heparin in the specimen or specimen type Evaluating hypofibrinogenemia or dysfibrinogenemia in conjunction with the TT and fibrinogen...

SP5TC - Overview: Septin-5 Antibody, Tissue Immunofluorescence, Spinal Fluid

Detecting septin-5 IgG in spinal fluid (CSF) specimens Reporting an end titer result from CSF specimens

DCTR - Overview: Direct Antiglobulin Test (Polyspecific), Blood

Demonstrating in vivo coating of red blood cells with IgG or the complement component C3d in the following settings: -Autoimmune hemolytic anemia -Hemolytic transfusion reactions -Drug-induced hemolytic anemia

DSAC - Overview: Disaccharidase Activity Panel, Tissue

Evaluation of patients who present with signs or symptoms suggestive of disaccharidase disorders This test is not intended for carrier detection.

CCTR - Overview: Calcium/Creatinine Ratio, Random, Urine

Calculation of calcium concentration per creatinine concentration

AFOLR - Overview: Folate Receptor Alpha (FOLR1), Semi-Quantitative Immunohistochemistry, Manual

Diagnosis of epithelial ovarian cancer that may be eligible for treatment with an anti-folate receptor 1 protein antibody

11_IS - Overview: Factor XI Inhibitor Screen, Plasma

Detecting the presence of a specific factor inhibitor directed against coagulation factor XI

F9_IS - Overview: Factor IX Inhibitor Screen, Plasma

Detecting the presence of a specific factor inhibitor directed against coagulation factor IX

10_IS - Overview: Factor X Inhibitor Screen, Plasma

Detecting the presence of a specific factor inhibitor directed against coagulation factor X

F5_IS - Overview: Factor V Inhibitor Screen, Plasma

Detecting the presence of a specific factor inhibitor directed against coagulation factor V

FIBAG - Overview: Fibrinogen Antigen, Plasma

Evaluation of fibrinogen deficiency Measuring fibrinogen in patients with elevated plasma levels of fibrin degradation products, patients receiving heparin, and in patients with antibodies to thrombin (following surgical use of topical...

MTXSG - Overview: Methotrexate Post Glucarpidase, Serum

Monitoring methotrexate concentrations post-glucarpidase therapy Documenting failure to respond that may be due to noncompliance Guiding dosage adjustments in patients with kidney failure

URCU - Overview: Uric Acid, 24 Hour, Urine

Assessment and management of patients with kidney stones, particularly uric acid stones

TAKRO - Overview: Tacrolimus, Blood

Monitoring whole blood tacrolimus concentration during therapy, particularly in individuals coadministered cytochrome P450 (CYP) 3A4 substrates, inhibitors, or inducers Adjusting dose to optimize immunosuppression while minimizing...

TBGI - Overview: Thyroxine-Binding Globulin (TBG), Serum

Cases in which total thyroid hormone levels do not correlate with the thyrometabolic status, most commonly with pregnancy or the use of contraceptive steroids

SPNC - Overview: Streptococcus pneumoniae Antigen, Spinal Fluid

Rapid diagnosis of pneumococcal meningitis

SP7TS - Overview: Septin-7 Antibody, Tissue Immunofluorescence Titer, Serum

Detecting septin-7 IgG in serum specimens Reporting an end titer result from serum specimens

EHOLG - Overview: Entamoeba histolytica Antibody, Serum

As an adjunct in the diagnosis of extraintestinal, invasive amebiasis

SVISC - Overview: Viscosity, Serum

Detection of increased viscosity Monitoring patients with hyperviscosity syndrome This test is not useful for patients with small concentrations of monoclonal proteins.

PQNRU - Overview: Porphyrins, Quantitative, Random, Urine

Preferred test to begin assessment for congenital erythropoietic porphyria and porphyria cutanea tarda and during symptomatic periods for acute intermittent porphyria, hereditary coproporphyria, and variegate porphyria when specimen...

ALFA - Overview: Alpha-Lactalbumin, IgE, Serum

Establishing a diagnosis of an allergy to alpha-lactalbumin Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or anaphylactic episode -To confirm...

AAMY - Overview: Alpha-Amylase, IgE, Serum

Establishing the diagnosis of an allergy to Alpha-Amylase Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or anaphylactic episode -To confirm sensitization...

BTROP - Overview: Blomia tropicalis, IgE, Serum

Establishing a diagnosis of an allergy to Blomia tropicalis Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or anaphylactic episode -To confirm...