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CORTU - Overview: Cortisol, Free, 24 Hour, Urine

Preferred screening test for Cushing syndrome Diagnosis of pseudo-hyperaldosteronism due to excessive licorice consumption Test may not be useful in the evaluation of adrenal insufficiency.

CTXP - Overview: Cerebrotendinous Xanthomatosis, Plasma

Evaluating patients with a clinical suspicion of cerebrotendinous xanthomatosis (CTX) using plasma specimens Monitoring of individuals with CTX on chenodeoxycholic acid (CDCA) therapy This test is not useful for the identification of...

E157C - Overview: Escherichia coli O157:H7 Culture, Feces

Determining whether Escherichia coli O157:H7 may be the cause of diarrhea Reflexive testing for Shiga toxin and/or E coli O157:H7 nucleic acid amplification test-positive feces This test is generally not useful for patients hospitalized...

PBGDW - Overview: Porphobilinogen Deaminase, Washed Erythrocytes

Confirmation of a diagnosis of acute intermittent porphyria using washed erythrocyte specimens

VWAG - Overview: von Willebrand Factor Antigen, Plasma

Diagnosis of von Willebrand disease (VWD) and differentiation of VWD subtype (in conjunction with von Willebrand factor ristocetin cofactor activity and factor VIII coagulant activity) Differentiation of VWD from hemophilia A (in...

JAKXB - Overview: JAK2 Exon 12 and Other Non-V617F Mutation Detection, Blood

Second-order testing to aid in the distinction between a reactive cytosis and a myeloproliferative neoplasm, particularly when a diagnosis of polycythemia is being considered, using blood specimens

PEAR - Overview: Pear, IgE, Serum

Establishing a diagnosis of an allergy to pear Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or anaphylactic episode -To confirm sensitization prior to...

PTU - Overview: Protein, Total, 24 Hour, Urine

Evaluation of kidney disease using a 24-hour urine collection Screening for monoclonal gammopathy

VLTB - Overview: Volatile Screen, Blood

Detection and quantitation of acetone, methanol, isopropanol, and ethanol in whole blood Quantification of the concentration of ethanol in blood that correlates with the degree of intoxication Evaluation of toxicity to the measured...

CPAPD - Overview: Conventional Smear-Diagnostic, Varies

Screening for cervical carcinoma and a number of infections of the female genital tract including human papillomavirus, herpes, Candida, and Trichomonas

PTSC - Overview: Prothrombin Time (PT), Plasma

Screening to identify a deficiency of one or more of the clotting factors of the extrinsic coagulation system (I, II, V, VII, X) due to hereditary deficiency or acquired conditions such as liver disease, vitamin K deficiency, or a specific...

POPSD - Overview: Poppy Seed, IgE, Serum

Establishing the diagnosis of an allergy to poppy seed Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or anaphylactic episode -To confirm sensitization...

DF - Overview: House Dust Mites/Dermatophagoides farinae, IgE, Serum

Establishing a diagnosis of an allergy to house dust mites/Dermatophagoides farinae Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or anaphylactic...

GGT - Overview: Gamma-Glutamyltransferase (GGT), Serum

Diagnosing and monitoring hepatobiliary disease, it is currently the most sensitive enzymatic indicator of liver disease Ascertaining whether observed elevations of alkaline phosphatase are due to skeletal disease (normal...

EHRC - Overview: Ehrlichia chaffeensis (HME) Antibody, IgG, Serum

An adjunct in the diagnosis of ehrlichiosis Seroepidemiological surveys of the prevalence of the infection in certain populations

GENRA - Overview: Gentamicin, Random, Serum

Monitoring adequacy of serum concentration during gentamicin therapy in specimens for which no collection timing information is provided

PBCU - Overview: Lead/Creatinine Ratio, Urine

Detecting clinically significant lead exposure using random urine specimens This test is not a substitute for blood lead screening.

LIPA1 - Overview: Lipoprotein(a), Serum

Cardiovascular disease (CVD) risk refinement in patients with moderate or high risk based on conventional risk factors or patients with clinical suspicion of residual CV risk not identified by other lipid parameters

AMLPC - Overview: Amylase, Pancreatic Cyst Fluid

Aiding in distinguishing between pseudocysts and other types of pancreatic cysts when used in conjunction with imaging studies, cytology, and other pancreatic cyst fluid tumor markers

AC1Q - Overview: Anti-C1q Antibodies, IgG, Serum

Evaluating patients with suspected anti-C1q vasculitis Predicting renal involvement in patients with systemic lupus erythematosus Detection of anti-C1q antibodies in serum

ASB - Overview: Arsenic, Blood

Detecting acute or very recent arsenic exposure Monitoring the effectiveness of therapy This test is not useful for evaluation of chronic arsenic exposure.

APTTP - Overview: Activated Partial Thromboplastin Time, Plasma

Monitoring heparin therapy (unfractionated heparin) Screening for certain coagulation factor deficiencies Detection of coagulation inhibitors such as lupus anticoagulant, specific factor inhibitors, and nonspecific inhibitors

ADNAS - Overview: Anti-DNase B Titer, Serum

Demonstration of acute or recent streptococcal infection using anti-DNase B titer

SASP - Overview: Aspergillus fumigatus, IgG Antibodies, Serum

Evaluation of patients suspected of having hypersensitivity pneumonitis (HP) induced by exposure to Aspergillus fumigatus Evaluation of patients suspected of having HP who have documented environmental exposures to high-humidity...

BIOTN - Overview: Biotin, Serum

Measurement of biotin in serum Assessment of biotin concentrations in individuals taking biotin supplements Investigation of unexpected results from immunoassays that utilize biotin-streptavidin detection methods This test is not useful...

CRTFR - Overview: Creatinine, Random, Urine

Normalizing urinary analytes to account for the variation in urinary concentrations between individuals when using random urine collections

CLU - Overview: Chloride, 24 Hour, Urine

Indication of fluid balance and acid-base homeostasis using a 24-hour urine collection

SFINC - Overview: Cerebrospinal Fluid (CSF) IgG Index, Spinal Fluid

Aiding in the diagnosis of multiple sclerosis and other central nervous system inflammatory conditions using cerebrospinal fluid specimens

NF4FS - Overview: Neurofascin-155 IgG4, Flow Cytometry, Serum

Evaluating patients with an underlying demyelinating neuropathy Diagnosis of a neurofascin-155 IgG4 mediated neuropathy

CARNP - Overview: Carbapenemase Detection-Carba NP Test, Varies

Confirming carbapenemase production from pure isolates of Enterobacterales or Pseudomonas aeruginosa

CUU - Overview: Copper, 24 Hour, Urine

Investigation of Wilson disease and obstructive liver disease using a 24-hour urine specimen

CDTA - Overview: Carbohydrate Deficient Transferrin, Adult, Serum

Indicating chronic alcohol abuse This test is not appropriate for screening patients for congenital disorders of glycosylation.

CURCU - Overview: Copper/Creatinine Ratio, Random, Urine

Investigation of Wilson disease and obstructive liver disease using a random urine specimen

CURC - Overview: Copper/Creatinine Ratio, Urine

Measurement of copper concentration of a part of the investigation of Wilson disease and obstructive liver disease using a random urine specimen

CRT2F - Overview: Creatinine, 24 Hour, Urine

Normalizing urinary analytes to account for the variation in urinary concentration

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NELL-1 [Test in Focus] - Insights

D., discusses how Mayo Clinic Laboratories’ new immunohistochemistry test for the detection of NELL-1 antigen, a biomarker for membranous nephropathy found in 10% to 15% of patients, provides diagnostic...

Looking Back on Clinical Chemistry 1 - Insights

in the Mayo Clinic Medical Laboratory Science program, takes a look back on her Clinical Chemistry 1 course....

Mayo Clinic Ranked No. 1 Hospital Nationwide by U.S. News & World Report - Insights

Report’s 29th annual "Best Hospitals Honor Roll" published online on August 14. Mayo Clinic also ranked No. 1 in more specialties than any other hospital in the country....

Orexin-A/Hypocretin-1 for the Diagnosis of Type 1 Narcolepsy [Test in Focus] - Insights

test to perform as well as to interpret. The orexin-A/hypocretin-1 test is a sensitive and specific alternative to the MSLT to diagnose type 1 narcolepsy....

Week in Review: November 1 - Insights

Top highlights include: Facebook launches into the digital space of healthcare, medical breakthrough for Ebola, and how the brain makes memories.