TCRF1 - Overview: T-Cell Receptor Beta (TCR Beta F1) Immunostain, Technical Component Only
Classification of lymphomas
ASYN - Overview: Alpha-Synuclein Immunostain, Technical Component Only
Identification of alpha-synuclein in neurogenerative disorders
HRPV8 - Overview: Human Herpes Virus, Type 8 (HHV-8) Immunostain, Technical Component Only
Identification of human herpes virus type 8 infection
HCG - Overview: Human Chorionic Gonadotropin (hCG) Immunostain, Technical Component Only
Identification human chorionic gonadotropin expression in neoplasms
HEPAT - Overview: Hepatocyte Immunostain, Technical Component Only
Distinguishing hepatocellular carcinoma from other types of cancer
HEPBC - Overview: Hepatitis B Core (HBc) Immunostain, Technical Component Only
Aiding in the identification of hepatitis B infection (chronic active state)
GFAP - Overview: Glial Fibrillary Acidic Protein Immunostain, Technical Component Only
Classification of glial tumors
GDCU - Overview: Gadolinium/Creatinine Ratio, Urine
Measurement of gadolinium concentration for assessing chronic exposure and monitoring effectiveness of dialysis using a random urine collection
HISME - Overview: Histone H3 Trimethyl K27 Immunostain, Technical Component Only
Diagnosis of malignant peripheral nerve sheath tumors and diffuse midline gliomas H3 K27M-mutant
FC13A - Overview: Factor 13a Immunostain, Technical Component Only
Aiding in the identification of acquired digital fibrokeratomas, angiofibromas, and oral fibroma, and a proportion of cells in histiocytomas
FOXP3 - Overview: FOXP3 Immunostain, Technical Component Only
Classification of leukemias and lymphomas
IHCFH - Overview: Fumarate Hydratase Immunostain, Technical Component Only
Identifying fumarate hydratase-deficient neoplasms Supporting the diagnosis of an atypical smooth muscle tumor over leiomyosarcoma
ERG - Overview: ERG Immunostain, Technical Component Only
Identification of erythroblast transformation specific (ETS)-related gene (ERG) protein expression
ESTR - Overview: Estrogen Receptor Immunostain, Technical Component Only
Qualitative detection of estrogen receptor alpha protein in a diagnostic setting
EHRCP - Overview: Ehrlichia Antibody Panel, Serum
An adjunct in the diagnosis of infection with Anaplasma phagocytophilum or Ehrlichia chaffeensis Seroepidemiological surveys of the prevalence of the infection in certain populations
PBUCR - Overview: Lead/Creatinine Ratio, Random, Urine
Detecting clinically significant lead exposure, a toxic heavy metal, using random urine specimens
JCHAI - Overview: J-Chain Immunostain, Technical Component Only
Classification of lymphomas
KRT20 - Overview: Keratin 20 (KRT20) Immunostain, Technical Component Only
Aids in determining the primary site in carcinomas of unknown origin
MUCN2 - Overview: Mucin 2, Immunostain, Technical Component Only
Aiding in subtyping intraductal papillary mucinous neoplasms
Aids in diagnosing plasma cell neoplasms
PBUOE - Overview: Lead Occupational Exposure, Random, Urine
Detecting clinically significant lead exposure due to occupational exposure This test is not a substitute for blood lead screening.
LUTHI - Overview: Luteinizing Hormone (LH) Beta Immunostain, Technical Component Only
Classification of pituitary adenomas
IDH2 - Overview: IHD2, R172K Mutation, Immunostain, Technical Component Only
Identification of IDH2 R172K mutant protein in angioimmunoblastic T-cell lymphoma or acute myeloid leukemia
IGMI - Overview: IgM Immunostain, Technical Component Only
Classification of lymphomas and multiple myeloma
LMO2 - Overview: LIM Domain Only 2 (LMO2) Immunostain, Technical Component Only
Classification of lymphomas
LYSOZ - Overview: Lysozyme Immunostain, Technical Component Only
Aiding in confirmation of monocytic and histiocytic differentiation
LACTO - Overview: Lactotransferrin Immunostain, Technical Component Only
Identifying the presence of lactotransferrin in amyloid deposits An adjunct to amyloid-subtyping analysis by mass spectrometry
ATRX - Overview: ATRX Immunostain, Technical Component Only
Distinguishing differentiated from undifferentiated neoplasms
AREC - Overview: Androgen Receptor Immunostain, Technical Component Only
Identification of tumors that express androgen receptor
ADV - Overview: Adenovirus Immunostain, Technical Component Only
Identification of adenovirus infection
SMACN - Overview: Actin, Smooth Muscle (SMActin) Immunostain, Technical Component Only
Identification of cells expressing the alpha-smooth muscle isoform of actin
BRACH - Overview: Brachyury Immunostain, Technical Component Only
Aiding in the identification of chordomas
BCOR - Overview: BCOR Immunostain, Technical Component Only
Aiding in the distinction of a subset of primitive round cell sarcomas with BCOR rearrangements from other Ewing/Ewing-like sarcomas
BCATN - Overview: Beta-Catenin Immunostain, Technical Component Only
Identification of aberrant nuclear staining pattern observed in some tumors
BCL2 - Overview: BCL-2 Immunostain, Technical Component Only
Classification of lymphomas
BRG1 - Overview: BRG1 (SMARCA4) Immunostain, Technical Component Only
Diagnosing ovarian small cell carcinoma of hypercalcemic type (SCCOHT)
BHISC - Overview: Bone Histomorphometry, Gross Microscopic Exam
Undetermined metabolic bone disease in wet tissue specimens Renal osteodystrophy Osteomalacia Osteoporosis Paget disease Assessing effects of therapy Identification of some disorders of the hematopoietic system Aluminum...
CRWB - Overview: Chromium, Blood
Monitoring exposure to chromium using whole blood specimens Monitoring metallic prosthetic implant wear
CD5 - Overview: CD5 Immunostain, Technical Component Only
Marker of T-cell lineage Phenotyping B-cell lymphomas
CD3I - Overview: CD3 Immunostain, Technical Component Only
Demonstrating T-cell lineage
CD23 - Overview: CD23 Immunostain, Technical Component Only
Identification of follicular dendritic cells Classification of low-grade B-cell lymphomas
CD30 - Overview: CD30 Immunostain, Technical Component Only
Identification of CD30 expression in a variety of neoplasms
CD33 - Overview: CD33 Immunostain, Technical Component Only
Classification of myeloid neoplasms and acute leukemias
MYC - Overview: MYC Immunostain, Technical Component Only
Assessment of MYC expression
MYOGE - Overview: Myogenin Immunostain, Technical Component Only
Marker of skeletal muscle differentiation
MUCN4 - Overview: Mucin 4, Immunostain, Technical Component Only
Aids in the differentiation of sarcomatoid carcinoma from sarcomatoid mesothelioma
MALI - Overview: MAL Immunostain, Technical Component Only
Diagnosis of primary mediastinal large B-cell lymphoma
MERKC - Overview: Merkel CC (MCPyV) Immunostain, Technical Component Only
Identification of Merkel cell polyomavirus infected cells
NF2F - Overview: Neurofilament (2F11) Immunostain, Technical Component Only
Aiding in the identification of neoplastic cells of neural origin or those exhibiting neuronal differentiation
OLIG2 - Overview: OLIG2 Immunostain, Technical Component Only
Distinguishing gliomas from neurocytomas and ependymomas
Mayo Clinic Ranked No. 1 Hospital Nationwide by U.S. News & World Report - Insights
Report’s 29th annual "Best Hospitals Honor Roll" published online on August 14. Mayo Clinic also ranked No. 1 in more specialties than any other hospital in the country....
NELL-1 [Test in Focus] - Insights
D., discusses how Mayo Clinic Laboratories’ new immunohistochemistry test for the detection of NELL-1 antigen, a biomarker for membranous nephropathy found in 10% to 15% of patients, provides diagnostic...
Looking Back on Clinical Chemistry 1 - Insights
in the Mayo Clinic Medical Laboratory Science program, takes a look back on her Clinical Chemistry 1 course....
Detection of (1→3)-𝝱-D-glucan as a Marker of Invasive Fungal Disease - Insights
In this month’s “Hot Topic,” Elitza Theel, Ph.D., will discuss the detection of (1→3)-β-D-glucan (BDG) in serum as a biomarker for the presence of invasive fungal infections....
Orexin-A/Hypocretin-1 for the Diagnosis of Type 1 Narcolepsy [Test in Focus] - Insights
test to perform as well as to interpret. The orexin-A/hypocretin-1 test is a sensitive and specific alternative to the MSLT to diagnose type 1 narcolepsy....