DESG3 - Overview: Desmoglein 3 (DSG3) Immunostain, Technical Component Only
Classification of squamous cell carcinomas
DESMN - Overview: Desmin Immunostain, Technical Component Only
Identification of striated and smooth muscle cells and tumors derived from this cell type
EBNA2 - Overview: Epstein Barr Nuclear Antigen 2 (EBNA2) Immunostain, Technical Component Only
Identification of Epstein Barr virus infection in normal, inflammatory, and neoplastic tissues
GLYP3 - Overview: Glypican-3 Immunostain, Technical Component Only
Differentiating hepatocellular carcinomas from other malignancies and hepatic adenomas
PCEAI - Overview: Carcinoembryonic Antigen, Polyclonal Immunostain, Technical Component Only
Marker of epithelial cells
MOLPS - Overview: Molybdenum, Serum
Monitoring of parenteral nutrition Monitoring metallic prosthetic implant wear As an indicator of molybdenum cofactor deficiency
CASF - Overview: IgG/Albumin Ratio, Spinal Fluid
Assessment of cerebrospinal fluid (CSF) IgG/albumin ratio in the absence of a paired CSF and serum specimen
GATAB - Overview: GATA-Binding Protein 3 Immunostain, Technical Component Only, Bone Marrow,
Characterizing carcinomas, including primary bladder and breast carcinomas, and some types of mesenchymal and neuroectodermal tumors
GLUTS - Overview: Glutamine Synthetase Immunostain, Technical Component Only
Classification of hepatic adenomas and the identification of focal nodular hyperplasia
Determination of T-cell clonality in T-cell neoplasms
TRBC1 - Overview: T-Cell Receptor Constant Beta Chain (TRBC1) Immunostain, Technical Component Only
Determination of T-cell clonality in T-cell neoplasms
UBIQ - Overview: Ubiquitin (UBIQ) Immunostain, Technical Component Only
Classification of neurodegenerative diseases
P40NA - Overview: p40 + Napsin A Immunostain, Technical Component Only
p40 aids in the classification of carcinomas and lymphomas Napsin A aids in the identification of primary lung adenocarcinoma
CD35 - Overview: CD35 Immunostain, Technical Component Only
Identification of follicular dendritic cells and granulocytes
TRK - Overview: Tropomyosin Receptor Kinase (TRK) Immunostain, Technical Component Only
Helpful in the screening for neurotrophic tyrosine receptor kinase (NTRK) rearranged tumors
LAIHC - Overview: Lambda Light Chain Immunostain, Technical Component Only
A marker of B-cell and plasma cell clonality and B-cell lineage
KAIHC - Overview: Kappa Light Chain Immunostain, Technical Component Only
A marker of clonality and B-cell lineage
2OHGP - Overview: 2-Hydroxyglutaric Aciduria Gene Panel, Varies
Follow up for abnormal biochemical results suggestive of 2-hydroxyglutaric aciduria Establishing a molecular diagnosis for patients with 2-hydroxyglutaric aciduria Identifying variants within genes known to be associated with...
CHDGG - Overview: Congenital Heart Disease Gene Panel, Varies
Providing a genetic evaluation for patients with a personal or family history of congenital heart disease Establishing a diagnosis of a genetic condition associated with congenital heart disease
ALPSG - Overview: Autoimmune Lymphoproliferative Syndrome (ALPS) Gene Panel, Varies
Providing a comprehensive genetic evaluation for patients with a personal or family history suggestive of autoimmune lymphoproliferative syndrome (ALPS) or related disorders Establishing a diagnosis of ALPS or a related disorder, allowing...
MUPAN - Overview: Comprehensive Neuromuscular Gene Panel, Varies
Establishing a molecular diagnosis for patients with a neuromuscular disorder Identifying variants within genes known to be associated with neuromuscular disorders allowing for predictive testing of at-risk family members
MPAGP - Overview: Methylmalonic Aciduria-Propionic Aciduria Combined Gene Panel, Varies
Follow up for abnormal biochemical results suggestive of methylmalonic acidemia or propionic acidemia Establishing a molecular diagnosis for patients with methylmalonic acidemia or propionic acidemia Identifying variants within genes...
BRBPS - Overview: Broad Range Bacterial PCR and Sequencing, Varies
Detecting and identifying bacteria (including mycobacteria) from normally sterile sources, including synovial fluid; body fluids such as pleural, peritoneal, and pericardial fluids, cerebrospinal fluid; and both fresh and formalin-fixed...
Comprehensive evaluation of the GATA2 gene in patients with clinical or immunological symptoms suggestive of GATA-binding protein 2 (GATA2) deficiency Screening family members of patients with confirmed GATA2 deficiency
Detection of high-risk (HR) genotypes associated with the development of cervical cancer Aids in triaging women with abnormal Pap smear results Individual genotyping of human papillomavirus (HPV)-16 and/or HPV-18 if present Results of...
LYNCP - Overview: Lynch Syndrome Panel, Varies
Establishing a diagnosis of Lynch syndrome or constitutional mismatch repair deficiency allowing for targeted cancer surveillance based on associated risks Identifying MLH1, MSH2, MSH6, PMS2, or EPCAM variants to allow for predictive...
CLADP - Overview: Congenital Lactic Acidosis Panel, Varies
Follow up for abnormal biochemical results suggestive of congenital lactic acidosis Establishing a molecular diagnosis for patients with congenital lactic acidosis Identifying variants within genes known to be associated with congenital...
Providing a genetic evaluation for patients with a personal or family history suggestive of a hereditary form of nephrocalcinosis, nephrolithiasis, or renal electrolyte imbalance Establishing a diagnosis for a variety of hereditary...
KS - Overview: Potassium, Serum
Evaluation of electrolyte balance, cardiac arrhythmia, muscular weakness, hepatic encephalopathy, and renal failure
HPVE6 - Overview: Human Papillomavirus (HPV) High-Risk E6/E7, RNA In Situ Hybridization
Stratification of oropharyngeal squamous cell carcinoma
Evaluating patients with suspected autoimmune encephalitis and autoimmune epilepsy using spinal fluid specimens
LACS1 - Overview: Lactate, Plasma
Diagnosing and monitoring patients with lactic acidosis
ADMI - Overview: ADAMTS13 Interpretation
Technical interpretation of testing performed to assist in the diagnosis of congenital, immune, or acquired thrombotic thrombocytopenic purpura
ALB - Overview: Albumin, Serum
Assessing nutritional status
BHISI - Overview: Bone Histomorphometry, Consultant Interpretation, Slides Only
Identifying undetermined metabolic bone disease in submitted slide specimens Diagnosing renal osteodystrophy Diagnosing osteomalacia Diagnosing osteoporosis Diagnosing Paget disease Assessing the effects of therapy Identifying...
SP5CS - Overview: Septin-5 Antibody, Cell Binding Assay, Serum
Detecting septin-5 IgG by cell-binding assay using serum specimens
RAT10 - Overview: Citrate/Creatinine Ratio, Urine
Calculating the citrate concentration per creatinine Diagnosing risk factors for patients with calcium kidney stones Monitoring results of therapy in patients with calcium stones or renal tubular acidosis
PHU_ - Overview: pH, Random, Urine
Assessment of patients with metabolic acidosis Assessment of crystalluria Monitoring the effectiveness of alkalinization or acidification of urine for certain medical conditions (eg, treatment of uric acid nephrolithiasis)
PERAM - Overview: Perampanel, Serum
Monitoring serum concentration of perampanel, in specific clinical conditions (ie, severe kidney impairment, mild to moderate hepatic impairment, and end-stage kidney disease) Assessing compliance Assessing potential toxicity
HPVLR - Overview: Human Papillomavirus (HPV) Low Risk, In Situ Hybridization
Detection of human papillomavirus from low-risk genotypes (6, 11)
SP5CC - Overview: Septin-5 Antibody, Cell-Binding Assay, Spinal Fluid
Detecting septin-5 IgG by cell-binding assay using cerebrospinal fluid specimens
REVE0 - Overview: Erythrocytosis Summary Interpretation
Incorporating and summarizing subsequent results into an overall interpretation for the REVE2 / Erythrocytosis Evaluation, Blood
PMSBB - Overview: Postmortem Screening, Bile and Blood Spot
Postmortem evaluation of individuals at any age who died suddenly or unexpectedly; testing is particularly recommended under the following circumstances (risk factors): -Family history of sudden infant death syndrome or other sudden...
VHLZZ - Overview: Von Hippel Lindau Syndrome, VHL, Full Gene Analysis, Varies
Evaluating patients with a personal or family history suggestive of Von Hippel-Lindau (VHL) syndrome Establishing a diagnosis of a VHL allowing for targeted cancer surveillance based on associated risks Identifying genetic variants...
RBART - Overview: Bartter Syndrome Gene Panel, Varies
Providing a genetic evaluation for patients with a personal or family history suggestive of Bartter syndrome Establishing a diagnosis of Bartter syndrome
MSP3 - Overview: Multiple Sclerosis (MS) Cascade, Serum and Spinal Fluid
Diagnosing multiple sclerosis, especially helpful in patients with equivocal clinical or radiological findings
SQTSG - Overview: Short QT Syndrome Gene Panel, Varies
Providing a genetic evaluation for patients with a personal or family history suggestive of short QT syndrome Establishing a diagnosis of short QT syndrome
Screening for hepatitis C virus (HCV) infection in primary care settings in high-risk persons with a current or previous history of illicit injection drug use or a history of receiving a blood transfusion prior to 1992 Screening for...
WESMT - Overview: Whole Exome and Mitochondrial Genome Sequencing, Varies
Serving as a first-tier test to identify a molecular and/or mitochondrial diagnosis in patients with suspected genetic disorders, which can allow for: -Better understanding of the natural history/prognosis -Targeted management (anticipatory...
CLLDF - Overview: Chronic Lymphocytic Leukemia, Diagnostic FISH, Varies
Detecting recurrent common chromosome abnormalities in patients with chronic lymphocytic leukemia (CLL) Distinguishing patients with 11;14 translocations who have the leukemic phase of mantle cell lymphoma from patients who have...
Mayo Clinic Ranked No. 1 Hospital Nationwide by U.S. News & World Report - Insights
Report’s 29th annual "Best Hospitals Honor Roll" published online on August 14. Mayo Clinic also ranked No. 1 in more specialties than any other hospital in the country....
NELL-1 [Test in Focus] - Insights
D., discusses how Mayo Clinic Laboratories’ new immunohistochemistry test for the detection of NELL-1 antigen, a biomarker for membranous nephropathy found in 10% to 15% of patients, provides diagnostic...
Looking Back on Clinical Chemistry 1 - Insights
in the Mayo Clinic Medical Laboratory Science program, takes a look back on her Clinical Chemistry 1 course....
Detection of (1→3)-𝝱-D-glucan as a Marker of Invasive Fungal Disease - Insights
In this month’s “Hot Topic,” Elitza Theel, Ph.D., will discuss the detection of (1→3)-β-D-glucan (BDG) in serum as a biomarker for the presence of invasive fungal infections....
Orexin-A/Hypocretin-1 for the Diagnosis of Type 1 Narcolepsy [Test in Focus] - Insights
test to perform as well as to interpret. The orexin-A/hypocretin-1 test is a sensitive and specific alternative to the MSLT to diagnose type 1 narcolepsy....