Test Catalog

Test Id : PHU_

pH, Random, Urine

Useful For
Suggests clinical disorders or settings where the test may be helpful

Assessment of patients with metabolic acidosis

 

Assessment of crystalluria

 

Monitoring the effectiveness of alkalinization or acidification of urine for certain medical conditions (eg, treatment of uric acid nephrolithiasis)

Method Name
A short description of the method used to perform the test

pH meter

NY State Available
Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Reporting Name
Lists a shorter or abbreviated version of the Published Name for a test

pH, Random, U

Specimen Type
Describes the specimen type validated for testing

Urine

Specimen Required
Defines the optimal specimen required to perform the test and the preferred volume to complete testing

Supplies: Urine Tubes, 10 mL (T068)

Container/Tube: Plastic, 10-mL urine tube

Specimen Volume: 10 mL

Collections Instructions: Collect a random urine specimen.

Specimen Minimum Volume
Defines the amount of sample necessary to provide a clinically relevant result as determined by the Testing Laboratory

1 mL

Reject Due To
Identifies specimen types and conditions that may cause the specimen to be rejected

  All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Specimen Stability Information
Provides a description of the temperatures required to transport a specimen to the performing laboratory, alternate acceptable temperatures are also included

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 7 days
Frozen 7 days

Useful For
Suggests clinical disorders or settings where the test may be helpful

Assessment of patients with metabolic acidosis

 

Assessment of crystalluria

 

Monitoring the effectiveness of alkalinization or acidification of urine for certain medical conditions (eg, treatment of uric acid nephrolithiasis)

Clinical Information
Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

Urine pH is a measure of the acidity/alkalinity of urine and, by itself, usually provides little useful information. Under normal conditions its value is influenced by the type of diet (some diets: eg, diets rich in meat-having more acid content than others, eg, vegetarian diets). Assessment of urine pH may be useful in the evaluation of systemic acid-base disorder. For example, the normal response during metabolic acidosis is a lowering of the urine pH to less than 5. If it is greater than 5, then a defect in urine acidification should be considered. Often a urine pH above 8 is suggestive of infection of a urea splitting organism such as Proteus mirabilis. Monitoring of urine pH may also be helpful during therapeutic interventions to either alkalinize the urine (such as for treatment of uric acid nephrolithiasis) or acidify the urine. Finally, when assessing crystalluria, noting the urine pH may be helpful since some crystals have a propensity to form in alkaline urine while others form in relative acidic urine.

Reference Values
Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

4.5 to 8.0

Interpretation
Provides information to assist in interpretation of the test results

Dependent on clinical condition.

Cautions
Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances

A pH greater than 8 suggests the presence of urinary tract infection with a urea splitting organism.

Clinical Reference
Recommendations for in-depth reading of a clinical nature

1. Menezes CJ, Worcester EM, Coe FL, Asplin J, Bergsland KJ, Ko B: Mechanisms for falling urine pH with age in stone formers. Am J Physiol Renal Physiol. 2019 Jul 1;317(7):F65-F72. doi: 10.1152/ajprenal.00066.2019

2. Ilyas R, Cho K, Young JG: What is the best method to evaluate urine pH? A trial of three urinary pH measurement methods in a stone clinic. J Endourol. 2015 Jan;29(1):70-4. doi: 10.1089/end.2014.0317

3. Davidsohn I, Henry JB: Todd-Sanford Clinical Diagnosis by Laboratory Methods; 15th ed. Elsevier; 1974:43-44

4. Free AH, Free HBS: Urodynamics, concepts relating to urinalysis. Ames Co; 1974;57-61

5. Kaplan LA, Pesce AJ: Clinical Chemistry: Theory, Analysis, Correlation. 3rd ed. Mosby-Year Book Inc; 1996:823

Method Description
Describes how the test is performed and provides a method-specific reference

The pH meter is composed of a glass electrode, calomel electrode and voltmeter. The glass electrode has a fixed acid concentration, yielding a corresponding voltage. The calomel electrode is the reference electrode. Its voltage is independent of the H+ ion concentration. The two electrodes constitute a galvanic cell whose electromotive force is measured by the voltmeter. The meter is calibrated to read in pH units, reflecting the H+ ion concentration. The meter is used to determine pH in 0 to 14 range.(Instruction manual: Fisher Scientific accumet Basic (AB) Benchtop Meters. Fisher Scientific; 68x613601.0 07/2012)

PDF Report
Indicates whether the report includes an additional document with charts, images or other enriched information

No

Day(s) Performed
Outlines the days the test is performed. This field reflects the day that the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time before the test is performed. Some tests are listed as continuously performed, which means that assays are performed multiple times during the day.

Monday through Sunday

Report Available
The interval of time (receipt of sample at Mayo Clinic Laboratories to results available) taking into account standard setup days and weekends. The first day is the time that it typically takes for a result to be available. The last day is the time it might take, accounting for any necessary repeated testing.

Same day/1 day

Specimen Retention Time
Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded

2 days

Performing Laboratory Location
Indicates the location of the laboratory that performs the test

Rochester

Fees
Several factors determine the fee charged to perform a test. Contact your U.S. or International Regional Manager for information about establishing a fee schedule or to learn more about resources to optimize test selection.

  • Authorized users can sign in to Test Prices for detailed fee information.
  • Clients without access to Test Prices can contact Customer Service 24 hours a day, seven days a week.
  • Prospective clients should contact their Regional Manager. For assistance, contact Customer Service.

Test Classification
Provides information regarding the medical device classification for laboratory test kits and reagents. Tests may be classified as cleared or approved by the US Food and Drug Administration (FDA) and used per manufacturer instructions, or as products that do not undergo full FDA review and approval, and are then labeled as an Analyte Specific Reagent (ASR) product.

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information
Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Clinic Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.

CPT codes are provided by the performing laboratory.

83986

LOINC® Information
Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the order and results codes of this test. LOINC values are provided by the performing laboratory.

Test Id Test Order Name Order LOINC Value
PHU_ pH, Random, U 2756-5
Result Id Test Result Name Result LOINC Value
Applies only to results expressed in units of measure originally reported by the performing laboratory. These values do not apply to results that are converted to other units of measure.
PHU_ pH, Random, U 2756-5

Test Setup Resources

Setup Files
Test setup information contains test file definition details to support order and result interfacing between Mayo Clinic Laboratories and your Laboratory Information System.

Excel | Pdf

Sample Reports
Normal and Abnormal sample reports are provided as references for report appearance.

Normal Reports | Abnormal Reports

SI Sample Reports
International System (SI) of Unit reports are provided for a limited number of tests. These reports are intended for international account use and are only available through MayoLINK accounts that have been defined to receive them.

SI Normal Reports | SI Abnormal Reports