ALBS1 - Overview: Albumin, Serum
Assessing nutritional status Aiding in the diagnosis of multiple sclerosis when used in conjunction with serum IgG, and cerebrospinal fluid IgG and albumin concentrations
NH3V - Overview: Ammonia, Plasma
Assisting in the diagnosis of hepatic coma Investigating and monitoring treatment for inborn errors of metabolism Evaluating patients with advanced liver disease
OSMOF - Overview: Osmolality, Feces
Measurement of osmolality for the workup of cases of chronic diarrhea Diagnosis of factitious diarrhea (where patient adds fluid to stool to simulate diarrhea)
MMAGP - Overview: Methylmalonic Aciduria Gene Panel, Varies
Follow up for abnormal biochemical results suggestive of a methylmalonic acidemia Establishing a molecular diagnosis for patients with methylmalonic acidemia Identifying variants within genes known to be associated with methylmalonic...
GNF13 - Overview: Factor XIII Deficiency, F13A1 and F13B Genes, Next-Generation Sequencing, Varies
Evaluating factor XIII deficiency (FXIIID) in patients with a personal or family history suggestive of FXIIID Confirming an FXIIID diagnosis with the identification of known or suspected disease-causing alterations in the F13A1 or F13B...
OCT4 - Overview: OCT3/4 Immunostain, Technical Component Only
Identification of germ cell tumors
POU2F - Overview: POU2F3 Immunostain, Technical Component Only
Diagnosis of a variant of small cell lung carcinoma
TTIGS - Overview: Tetanus Toxoid IgG Antibody, Serum
Assessing antibody response to the tetanus toxoid vaccine, which should be performed at least 3 weeks after immunization Aiding in the evaluation of immunodeficiency This test should not be used to diagnose tetanus infection.
TFE3I - Overview: Transcription Factor E3 (TFE3) Immunostain, Technical Component Only
Assessment of transcription factor E3 expression
TIS - Overview: Titanium, Serum
Monitoring metallic prosthetic implant wear
VIPI - Overview: Vasoactive Intestine Polypeptide (VIP), Technical Component Only
Aiding in the identification of islet cell tumors
RALB1 - Overview: Albumin, Random, Urine
Assessing the potential for early onset of nephropathy in diabetic patients using random urine specimens
CD273 - Overview: CD273 (PD-L2) Immunostain, Technical Component Only
Differentiation of primary mediastinal large B-cell lymphoma from diffuse large B cell-lymphoma
PACPI - Overview: Prostatic Acid Phosphatase (PACP) Immunostain, Technical Component Only
Identification of normal prostatic epithelium and prostatic adenocarcinoma
PSAIM - Overview: Prostate Specific Antigen (PSA) Immunostain, Technical Component Only
Marker of glandular epithelium in normal and neoplastic prostate
CD13 - Overview: CD13 Immunostain, Technical Component Only
Marker of myeloid lineage
AMYPI - Overview: Amyloid P (SAP) Immunostain, Technical Component Only
Identification of amyloid deposits in tissue
SOX11 - Overview: SOX11 Immunostain, Technical Component Only
Identification of mantle cell lymphomas
TSH - Overview: Thyroid-Stimulating Hormone (TSH), Beta Immunostain, Technical Component Only
Part of a panel of immunostains used in the classification of pituitary adenomas
HNF1B - Overview: Hepatocyte Nuclear Factor 1Beta Immunostain, Technical Component Only
Diagnosis of ovarian clear cell carcinoma and endometrial clear cell carcinoma
HALO - Overview: Haloperidol, Serum
Optimizing haloperidol dosage Monitoring patient compliance Assessing toxicity
GATA3 - Overview: GATA Binding Protein 3 Immunostain, Technical Component Only
Characterizing carcinomas, including primary bladder and breast carcinomas, and some types of mesenchymal and neuroectodermal tumors
GALN3 - Overview: Galectin-3 Immunostain, Technical Component Only
Distinguishing normal and benign thyroid gland from thyroid carcinoma
EXT2 - Overview: Exostosin 2 (EXT2) Immunostain, Technical Component Only
Identification of exostosin 2 associated membranous nephropathy
IGAI - Overview: IgA Immunostain, Technical Component Only
Aiding in the classification of lymphomas and multiple myeloma
KIMEL - Overview: Ki67 + Melan A Immunostain, Technical Component Only
Ki67 is a marker of proliferation in neoplasms Melan A aids in the identification of melanoma
KRTAE - Overview: Keratin (AE1/AE3) Immunostain, Technical Component Only
Identification of cells expressing a broad spectrum of cytokeratins (low and high molecular weight keratins)
INHIB - Overview: Inhibin Immunostain, Technical Component Only
Identifying sex cord-stromal tumors
MTAP - Overview: Methylthioadenosine Phosphorylase (MTAP) Immunostain, Tech Only
Aiding in the diagnosis of malignant mesothelioma
APPI - Overview: Amyloid Precursor Protein (APP) Immunostain, Technical Component Only
Aids in the identification of amyloid precursor protein present in Alzheimer disease
AAH - Overview: Amyloid A (Hepatic) Immunostain, Technical Component Only
Classification of hepatic adenomas This test is not useful for amyloid typing.
BRAFV - Overview: BRAF V600E Immunostain, Technical Component Only
Identification of BRAF V600E-mutated protein
BHSF - Overview: Beta-Human Chorionic Gonadotropin, Quantitative, Spinal Fluid
Aiding in the diagnosis of brain metastases of testicular cancer or extragonadal intracerebral germ cell tumors
BIOTS - Overview: Biotinidase, Serum
Preferred test for the diagnosis of biotinidase deficiency Follow-up testing for certain organic acidurias
CD303 - Overview: CD303 (BDCA-2) Immunostain, Technical Component Only
Diagnosis of blastic plasmacytoid dendritic cell neoplasm
CD4I - Overview: CD4 Immunostain, Technical Component Only
Identification of T helper cells, histiocytes, and monocytes
CAIX - Overview: Carbonic Anhydrase IX (CA-IX) Immunostain, Technical Component Only
Diagnosis of clear cell renal cell carcinoma and clear cell papillary renal cell carcinoma
MESOP - Overview: Mesothelioma Panel (WT1/KRT5/TTF1/pCEA) Immunostain, Technical Component Only
Differentiation of mesothelioma and non-small cell lung cancer
SGSS - Overview: Synthetic Glucocorticoid Screen, Serum
Confirming the presence of listed synthetic glucocorticoids (see Interpretation) Confirming the cause of secondary adrenal insufficiency This test is not useful for detection of fluticasone propionate.
SUDC - Overview: Sudden Cardiac Death Pathology Consultation
Identifying specific causes contributing to sudden cardiac death
SDHB - Overview: SDHB Immunostain, Technical Component Only
Aids in the identification of succinate dehydrogenase B-deficient tumors
NSEI - Overview: Neuron-Specific Enolase Immunostain, Technical Component Only
Characterization of neuroendocrine differentiation in tumors
SSX18 - Overview: Synovial Sarcoma Panel, Technical Component Only
Aiding in distinguishing synovial sarcomas from similar sarcomas
CDKPB - Overview: CD68 (KP1) Immunostain, Bone Marrow, Technical Component Only
Aiding in the identification of histocytic and myeloid lineage cells
CHRO - Overview: Chromogranin Immunostain, Technical Component Only
Aiding in the identification of tumors with neuroendocrine differentiation
CA153 - Overview: Cancer Antigen 15-3 (CA 15-3), Serum
Managing breast cancer patients when used in conjunction with clinical information and other diagnostic procedures Serial testing to assist in early detection of disease recurrence in previously treated stage II and III breast cancer...
CLZ - Overview: Clozapine, Serum
Monitoring patient compliance of clozapine treatment An aid to achieving desired serum levels
CBBRP - Overview: Coxiella burnetii (Q fever), Molecular Detection, PCR, Blood
Aiding in the diagnosis of Coxiella burnetii infection (eg, Q fever)
CD14I - Overview: CD14 Immunostain, Technical Component Only
Marker of histiocytic and monocytic lineage and follicular dendritic cells
CALPN - Overview: Calponin Immunostain, Technical Component Only
Marker for myoepithelium when differentiating ductal carcinomas in situ from infiltrating breast carcinoma Characterization of tumors of smooth muscle or myoepithelial lineage
Mayo Clinic Ranked No. 1 Hospital Nationwide by U.S. News & World Report - Insights
Report’s 29th annual "Best Hospitals Honor Roll" published online on August 14. Mayo Clinic also ranked No. 1 in more specialties than any other hospital in the country....
NELL-1 [Test in Focus] - Insights
D., discusses how Mayo Clinic Laboratories’ new immunohistochemistry test for the detection of NELL-1 antigen, a biomarker for membranous nephropathy found in 10% to 15% of patients, provides diagnostic...
Looking Back on Clinical Chemistry 1 - Insights
in the Mayo Clinic Medical Laboratory Science program, takes a look back on her Clinical Chemistry 1 course....
Detection of (1→3)-𝝱-D-glucan as a Marker of Invasive Fungal Disease - Insights
In this month’s “Hot Topic,” Elitza Theel, Ph.D., will discuss the detection of (1→3)-β-D-glucan (BDG) in serum as a biomarker for the presence of invasive fungal infections....
Orexin-A/Hypocretin-1 for the Diagnosis of Type 1 Narcolepsy [Test in Focus] - Insights
test to perform as well as to interpret. The orexin-A/hypocretin-1 test is a sensitive and specific alternative to the MSLT to diagnose type 1 narcolepsy....