Diagnosis of a neuromyelitis optica spectrum disorder (NMOSD) Diagnosis of autoimmune AQP4 channelopathy Distinguishing NMOSD from multiple sclerosis early in the course of disease
Predicting macrolide susceptibility in Mycoplasma (Mycoplasmoides) pneumoniae
TPPA - Overview: Syphilis Antibody, Treponema pallidum Particle Agglutination, Serum
An aid to resolve discrepant results between screening treponemal and non-treponemal assays This test is not recommended for general screening purposes for syphilis. This test should not be used to evaluate response to therapy. This test...
CTBID - Overview: Culture Referred for Identification, Mycobacterium and Nocardia, Varies
Rapid identification to the species level for Mycobacterium species, Nocardia species, and other aerobic actinomycete genera and species from pure culture isolates
DPYDZ - Overview: Dihydropyrimidine Dehydrogenase, DPYD Full Gene Sequencing, Varies
Identifying individuals at increased risk of toxicity when considering 5-fluorouracil and capecitabine chemotherapy treatment Identifying common and rare variants associated with decreased or absent dihydropyrimidine dehydrogenase (DPD)...
EBVAB - Overview: Epstein-Barr Virus Antibody Profile, Serum
Diagnosis of Epstein-Barr virus (EBV) infectious mononucleosis or other EBV related infections Identification of prior EBV infection as part of pre-immunosuppression screening This assay is not intended for viral isolation or...
GLIC - Overview: CD8 T-Cell Immune Competence, Global, Blood
Determining overimmunosuppression within the CD8 T-cell compartment, when used on transplant recipients and patients with autoimmune disorders receiving therapy with immunosuppressant agents
WESDX - Overview: Whole Exome Sequencing for Hereditary Disorders, Varies
Serving as a first-tier test to identify a molecular diagnosis in patients with suspected genetic disorders, which can allow for: -Better understanding of the natural history/prognosis -Targeted management (anticipatory guidance, management...
FPEPI - Overview: Pepsinogen I (PG I)
Pepsinogen I (PG I)
FWARP - Overview: Warfarin, Plasma
Warfarin, Plasma
FHADE - Overview: Haddock (Melanogrammus aeglefinus) IgE
Haddock (Melanogrammus aeglefinus) IgE
FAT1G - Overview: Anti-TIF-1gamma Antibody
Anti-TIF-1gamma Antibody
FOVAS - Overview: Ovarian Antibody Screen with Reflex to Titer, IFA
Ovarian Antibody Screen with Reflex to Titer, IFA
FCARO - Overview: Carotene, Beta
Confirm the diagnosis of carotenoderma; detect fat malabsorption; depressed carotene levels may be found in cases of steatorrhea.
FMETN - Overview: Metformin, Plasma
Metformin, Plasma
FRCE - Overview: Cedar Red (Juniperus virginiana) IgE
Cedar Red (Juniperus virginiana) IgE
FALPE - Overview: Alfalfa (Medicago sativa) IgE
Alfalfa (Medicago sativa) IgE
PSYCF - Overview: Psychosine, Spinal Fluid
Aiding in the biochemical diagnosis of Krabbe disease using cerebrospinal fluid specimens Follow-up of individuals affected with Krabbe disease Follow-up testing after an abnormal newborn screening result for Krabbe disease Monitoring...
TRYPT - Overview: Tryptase, Serum
Evaluation of individuals with suspected mast cell activation, which may occur as a result of anaphylaxis or allergen challenge Evaluation of patients with suspected mast cell activation syndrome Evaluation of patients with suspected...
T4 - Overview: T4 (Thyroxine), Total Only, Serum
Monitoring treatment with synthetic hormones (synthetic T3 [triiodothyronine] will cause a low total T4 [thyroxine]) Monitoring treatment of hyperthyroidism with thiouracil and other anti-thyroid drugs Index of thyroid function when the...
DCORT - Overview: 11-Deoxycortisol, Serum
Diagnostic workup of patients with congenital adrenal hyperplasia Part of metyrapone testing in the workup of suspected secondary or tertiary adrenal insufficiency Part of metyrapone testing in the differential diagnostic workup of...
HMGCR - Overview: 3-Hydroxy-3-Methylglutaryl Coenzyme-A (HMG-CoA) Reductase, Serum
Evaluating patients with suspected necrotizing autoimmune myopathy Measuring 3-hydroxy-3-methylglutaryl-CoA reductase antibodies
CLFAT - Overview: Cryptococcus Antigen Titer, Lateral Flow Assay, Spinal Fluid
Monitoring Cryptococcus antigen titers in cerebrospinal fluid Aiding in the diagnosis of cryptococcosis This test should not be used as a test of cure or to guide treatment decisions.
ROMA - Overview: ROMA Score (Ovarian Malignancy Risk Algorithm), Serum
Risk assessment for finding an ovarian malignancy during surgery in women who present with an adnexal mass The test is not intended as a screening or stand-alone diagnostic assay for ovarian cancer.
T4BPE - Overview: Thyroxine-Binding Protein Electrophoresis, Serum
Explaining unusual thyroxine (T4), free T4, and thyroxine-binding globulin test results that do not correlate with the patient's clinical presentation Detecting the presence of aberrant thyroxine-binding proteins, such as abnormal forms...
HBGCD - Overview: Hepatitis B Surface Antigen for Cadaveric or Hemolyzed Specimens, Serum
Testing cadaveric and hemolyzed blood specimens for hepatitis B surface antigen (HBsAg); US Food and Drug Administration-licensed for use with hemolyzed specimens Diagnosis of acute, recent (<6-month duration), or chronic hepatitis B...
HOLDC - Overview: Hematologic Disorders, Chromosome Hold, Varies
Holding the bone marrow or peripheral blood specimen in the laboratory but delaying chromosome analysis while preliminary morphologic assessment is in process
IL6DX - Overview: Interleukin-6, Serum
Evaluating patients with suspected chronic inflammatory disorders, such as rheumatoid arthritis, systemic lupus erythematosus, ankylosing spondylitis, or inflammatory bowel disease Evaluating patients with Castleman disease Evaluating...
Screening for colonization of extended-spectrum beta-lactamase (ESBL)-producing organisms in stool Screening fecal microbiota transplant donor feces for ESBL-producing organisms. This test is not intended for medicolegal use.
FLCS - Overview: Immunoglobulin Free Light Chains, Serum
Monitoring serum from patients with monoclonal light chain diseases without a M-spike on protein electrophoresis May be useful as a diagnostic test in patients in whom there is a suspicion of primary systemic amyloidosis, light chain...
BRAFD - Overview: BRAF V600E/V600K Somatic Mutation Analysis, Tumor
Therapy selection for patients with cancer (eg, melanomas that may respond to BRAF inhibitors, colon cancers that may not respond to EGFR inhibitors) Aiding in the diagnosis/prognosis of certain cancers (eg, hairy cell leukemia, papillary...
BETV2 - Overview: BET v2 (Profilin), IgE, Serum
Evaluation of patients suspected birch pollen allergy Evaluation of patients with suspected peanut allergy Evaluation of patients with oral allergy syndrome to other pollens or plant-based foods Testing for IgE antibodies is not useful...
Confirming the presence or absence of minimal residual disease in patients with known chronic lymphocytic leukemia who are either post-chemo/immunotherapy or post-bone marrow transplant
NSYPH - Overview: Syphilis IgG Enzyme Immunoassay, Serum
An aid in the diagnosis of infection with Treponema pallidum Routine prenatal screening This test is not useful for diagnosis of congenital syphilis. This test is not offered as a screening or confirmatory test for blood donor specimens.
PMET - Overview: Metanephrines, Fractionated, Free, Plasma
Screening test for presumptive diagnosis of catecholamine-secreting pheochromocytomas or paragangliomas
CMVP - Overview: Cytomegalovirus (CMV) Antibodies, IgM and IgG, Serum
Aiding in the diagnosis of acute or past infection with cytomegalovirus (CMV) Determining prior exposure to CMV This test should not be used for screening blood or plasma donors.
C341Q - Overview: Complement C3 and C4 with Anti-C1q Antibodies, Serum
Evaluating patients with suspected anti-C1q vasculitis Predicting renal involvement in patients with systemic lupus erythematosus
C1INF - Overview: C1 Esterase Inhibitor, Functional, Serum
Diagnosing hereditary angioedema Monitoring response to C1 esterase inhibitor replacement therapy
HAIGM - Overview: Hepatitis A Virus IgM Antibody, Serum
Diagnosis of acute or recent hepatitis A infection
PREGN - Overview: Pregnenolone, Serum
An ancillary test for congenital adrenal hyperplasia, particularly in situations in which a diagnosis of both 21- and 11-hydroxylase deficiency have been ruled out Confirming a diagnosis of 3-beta-hydroxy dehydrogenase deficiency
RNAP - Overview: RNA Polymerase III Antibodies, IgG, Serum
Evaluating patients suspected of having systemic sclerosis as part of systemic sclerosis criteria antibody tests Providing diagnostic and prognostic information in patients with systemic sclerosis
CDPCR - Overview: Clostridioides difficile Toxin, PCR, Feces
Sensitive, specific, and rapid diagnosis of Clostridioides (Clostridium) difficile-associated diarrhea and pseudomembranous colitis The test is not recommended as a test of cure.
PINP - Overview: Procollagen I Intact N-Terminal, Serum
Aiding in monitoring antiresorptive and anabolic therapy in patients with osteoporosis An adjunct in the assessment of conditions associated with increased bone turnover, such as Paget disease This test should not be used as a screening...
PNP - Overview: Platelet Neutralization Procedure, Plasma
Aiding in the confirmation or exclusion of the presence of a lupus anticoagulant (LAC) inhibitor when used in conjunction with other appropriate coagulation tests. Aids in differentiating deficiencies or inhibitors of specific coagulation...
PAX2 - Overview: PAX2 Immunostain, Technical Component Only
Aiding in the diagnosis of endocervical adenocarcinoma and renal cell carcinoma
WNGC - Overview: West Nile Virus Antibody, IgG, Spinal Fluid
Aids in diagnosing recent or past central nervous system West Nile virus infection
ZONI - Overview: Zonisamide, Serum
Monitoring zonisamide therapy; recommended for all patients to ensure appropriate dosing Assessing medication compliance
VIM - Overview: Vimentin Immunostain, Technical Component Only
Identification of cells of mesenchymal origin in normal and neoplastic tissues
IDH1 - Overview: IDH1 Mutation (R132H) Immunostain, Technical Component Only
Classification of gliomas
IL5P - Overview: Interleukin 5, Plasma
Evaluation of patients with disorders known to be associated with hypereosinophilia
NELL-1 [Test in Focus] - Insights
D., discusses how Mayo Clinic Laboratories’ new immunohistochemistry test for the detection of NELL-1 antigen, a biomarker for membranous nephropathy found in 10% to 15% of patients, provides diagnostic...
Looking Back on Clinical Chemistry 1 - Insights
in the Mayo Clinic Medical Laboratory Science program, takes a look back on her Clinical Chemistry 1 course....
Mayo Clinic Ranked No. 1 Hospital Nationwide by U.S. News & World Report - Insights
Report’s 29th annual "Best Hospitals Honor Roll" published online on August 14. Mayo Clinic also ranked No. 1 in more specialties than any other hospital in the country....
Orexin-A/Hypocretin-1 for the Diagnosis of Type 1 Narcolepsy [Test in Focus] - Insights
test to perform as well as to interpret. The orexin-A/hypocretin-1 test is a sensitive and specific alternative to the MSLT to diagnose type 1 narcolepsy....
Week in Review: November 1 - Insights
Top highlights include: Facebook launches into the digital space of healthcare, medical breakthrough for Ebola, and how the brain makes memories.