PBCU - Overview: Lead/Creatinine Ratio, Urine

Detecting clinically significant lead exposure using random urine specimens This test is not a substitute for blood lead screening.

LPSBF - Overview: Lipase, Body Fluid

Determining whether pancreatic inflammation or pancreatic fistula may be contributing to a pathological accumulation of fluid

KKBRP - Overview: Kingella kingae, Molecular Detection, PCR, Blood

Aiding in the diagnosis of Kingella kingae infection using whole blood specimens

KRT34 - Overview: Keratin (34BE12) Immunostain, Technical Component Only

Identification of cells expressing high-molecular-weight cytokeratin

KRT19 - Overview: Keratin 19 (KRT19) Immunostain, Technical Component Only

Aids in the identification of cells expressing low molecular weight cytokeratin (KRT19)

KIT - Overview: KIT Immunostain, Technical Component Only

Aids in the identification of gastrointestinal stromal tumors

LFABP - Overview: Liver Fatty Acid-Binding Protein (L-FABP) Immunostain, Technical Component Only

Classification of hepatic adenomas

MYOGL - Overview: Myoglobin Immunostain, Technical Component Only

Marker of skeletal and cardiac muscle

MCRPL - Overview: Macroprolactin, Serum

Determining biologically active levels of prolactin, in asymptomatic patients with elevated prolactin levels Ruling out the presence of macroprolactin

MOC31 - Overview: MOC-31 Immunostain, Technical Component Only

Marker of epithelial cells

MHBRP - Overview: Metamycoplasma hominis, Molecular Detection, PCR, Blood

Rapid, sensitive, and specific identification of Metamycoplasma hominis from whole blood This test is not intended for medicolegal use.

UPII - Overview: Uroplakin II Immunostain, Technical Component Only

Characterization of urothelial carcinoma

SEMA3 - Overview: Semaphorin 3B (SEMA3B) Immunostain, Technical Component Only

Aiding in the diagnosis of semaphorin 3B-associated membranous nephropathy

TRYPN - Overview: Trypsin Immunostain, Technical Component Only

Identifying cells with acinar differentiation in the pancreas

TRPTS - Overview: Tryptase Immunostain, Technical Component Only

A marker of mast cells

TTFSP - Overview: Thyroid Transcription Factor (SPT24) Immunostain, Technical Component Only

Part of a panel of immunostains to identify the primary site for carcinomas of unknown origin

TRK - Overview: Tropomyosin Receptor Kinase (TRK) Immunostain, Technical Component Only

Helpful in the screening for neurotrophic tyrosine receptor kinase (NTRK) rearranged tumors

SULFU - Overview: Sulfate, 24 Hour, Urine

Assessing the nutrition intake of animal protein The calculation of urinary supersaturation of various crystals or stones

TPIT - Overview: T-PIT Immunostain, Technical Component Only

Diagnosis of corticotroph, silent corticotroph, and null cell adenomas of the pituitary

T46CC - Overview: Tripartite Motif-Containing Protein 46 (TRIM46) IgG, Cell Binding Assay, Spinal Fluid

Detecting tripartite motif-containing protein 46 (TRIM46)-IgG by cell-binding assay using cerebrospinal fluid specimens Evaluation of an autoimmune/paraneoplastic neurological syndrome among patients presenting with cerebellar ataxia,...

SMOTH - Overview: Smoothelin Immunostain, Technical Component Only

Distinguishing muscularis mucosae from muscularis propria

STAT6 - Overview: Signal Transducer and Activator of Transcription 6 (STAT6), Technical Component Only

Aids in distinguishing solitary fibrous tumor from morphologic mimics

SALL4 - Overview: SALL4 Immunostain, Technical Component Only

Aids in the identification of germ cell tumors

TAUI - Overview: TAU Immunostain, Technical Component Only

Analysis of neurodegenerative disorders

TCRF1 - Overview: T-Cell Receptor Beta (TCR Beta F1) Immunostain, Technical Component Only

Classification of lymphomas

TBET - Overview: T-Box Expressed in T Cells (TBET) Immunostain, Technical Component Only

Classification of lymphomas

THYR - Overview: Thyroglobulin Immunostain, Technical Component Only

Classification of thyroid carcinoma

TIS - Overview: Titanium, Serum

Monitoring metallic prosthetic implant wear

SCERG - Overview: Saccharomyces cerevisiae Antibody, IgG, Serum

Measuring IgG anti-Saccharomyces cerevisiae antibodies as a part of a profile to aid in distinguishing between ulcerative colitis and Crohn disease in patients for whom the specific diagnosis is unclear based on endoscopic, pathologic, and...

VIM - Overview: Vimentin Immunostain, Technical Component Only

Identification of cells of mesenchymal origin in normal and neoplastic tissues

BUPM - Overview: Buprenorphine and Norbuprenorphine, Random, Urine

Monitoring of compliance utilizing buprenorphine Detection and confirmation of the illicit use of buprenorphine

INHIB - Overview: Inhibin Immunostain, Technical Component Only

Identifying sex cord-stromal tumors

AMIO - Overview: Amiodarone, Serum

Monitoring amiodarone therapy, especially when amiodarone is coadministered with other drugs that may interact Evaluating possible amiodarone toxicity Assessing patient compliance

BALAF - Overview: B-Cell Acute Lymphoblastic Leukemia/Lymphoma (ALL), FISH, Adult, Varies

Detecting, at diagnosis, recurrent common chromosome abnormalities associated with B-cell acute lymphoblastic leukemia/lymphoma (B-ALL/LBL) and Philadelphia chromosome-like acute lymphoblastic leukemia (Ph-like ALL) in adult patients As...

GNBLF - Overview: Bleeding Disorders, Focused Gene Panel, Next-Generation Sequencing, Varies

Evaluating hereditary bleeding in patients with a personal or family history suggestive of a hereditary bleeding disorder and initial laboratory testing results are suggestive for factors VII, VIII, IX, or XI deficiency, or a von Willebrand...

LDALD - Overview: Lysosomal and Peroxisomal Disorders Newborn Screen, Blood Spot

First-tier newborn screen for the lysosomal disorders: Fabry, Gaucher, Krabbe, mucopolysaccharidosis I (MPS I) and II (MPS II), infantile neurovisceral or chronic visceral acid sphingomyelinase deficiency, and Pompe (glycogen storage...

TALPF - Overview: T-Cell Acute Lymphoblastic Leukemia/Lymphoma (ALL), FISH, Pediatric, Varies

Detecting, at diagnosis, recurrent common chromosome abnormalities associated with T-cell acute lymphoblastic leukemia/lymphoma (T-ALL) in pediatric/young adult patients As an adjunct to conventional chromosome studies in pediatric/young...

CMITO - Overview: Combined Mitochondrial Full Genome and Nuclear Gene Panel, Varies

Diagnosing mitochondrial disease that results from variants in either nuclear-encoded genes or the mitochondrial genome A second-tier test for patients in whom previous targeted gene variant analyses for specific mitochondrial...

F8INP - Overview: Hemophilia A F8 Gene, Intron 1 and 22 Inversion Mutation Analysis, Prenatal

Prenatal testing for hemophilia A when a variant has not been identified in the family

F822P - Overview: Hemophilia A F8 Gene, Intron 22 Inversion Mutation Analysis, Prenatal

Prenatal testing for hemophilia A when a F8 intron 22 inversion has been identified in a family member

COGBM - Overview: Chromosome Analysis, Hematologic Disorders, Children's Oncology Group Enrollment Testing, Bone Marrow

Evaluation of pediatric bone marrow specimens for chromosomal abnormalities associated with hematologic malignancies for diagnostic and prognostic purposes in patients being considered for enrollment in Children's Oncology Group clinical...

CMACB - Overview: Chromosomal Microarray, Congenital, Blood

First-tier, postnatal testing for individuals with multiple anomalies that are not specific to well-delineated genetic syndromes, apparently nonsyndromic developmental delay or intellectual disability, or autism spectrum disorders as...

CORTO - Overview: Cortisol, Free and Total, Serum

Assessment of cortisol status in cases where there is known or a suspected abnormality in cortisol-binding proteins or albumin Assessment of adrenal function in the critically ill or stressed patient, thus preventing unnecessary use of...

F81P - Overview: Hemophilia A F8 Gene, Intron 1 Inversion Known Mutation Analysis, Prenatal

Prenatal testing for hemophilia A when a F8 intron 1 inversion has been identified in a family member

NONCM - Overview: Neuro-Oncology Gene Panel, Mutations Only, Tumor

Identifying mutations that may support a diagnosis or help determine prognosis for patients with central nervous system tumors Identifying specific mutations within genes known to be associated with response or resistance to specific...

STK1Z - Overview: Peutz-Jeghers Syndrome, STK11, Full Gene Analysis, Varies

Evaluating patients with a personal or family history suggestive of Peutz-Jeghers syndrome (PJS) Establishing a diagnosis of PJS allowing for targeted cancer surveillance based on associated risks Identifying variants within genes known...

PMARG - Overview: Postmortem Arrhythmia Gene Panel, Tissue

Providing a comprehensive postmortem genetic evaluation in the setting of a sudden death suspicious for cardiac arrhythmia or with a personal or family history suggestive of a hereditary form of cardiac arrhythmia Identifying a...

HTGR - Overview: Thyroglobulin, Tumor Marker Reflex, Serum

Reporting of accurate thyroglobulin results, depending on the antithyroglobulin antibodies status of the patient Accurate measurement of serum thyroglobulin in patients with known or suspected antithyroglobulin autoantibodies or possible...

EGFRW - Overview: EGFR Targeted Mutation Analysis with ALK Reflex, Tumor

Identifying non-small cell lung cancers that may benefit from treatment with epidermal growth factor receptor -targeted therapies or anaplastic lymphoma kinase inhibitors

CMSP - Overview: Inherited Congenital Myasthenic Syndrome Gene Panel, Varies

Establishing a molecular diagnosis for patients with congenital myasthenic syndrome Identifying variants within genes known to be associated with congenital myasthenic syndrome, allowing for predictive testing of at-risk family members