CDPCR - Overview: Clostridioides difficile Toxin, PCR, Feces
Sensitive, specific, and rapid diagnosis of Clostridioides (Clostridium) difficile-associated diarrhea and pseudomembranous colitis The test is not recommended as a test of cure.
MGRNA - Overview: Neisseria gonorrhoeae, Miscellaneous Sites, Nucleic Acid Amplification, Varies
Detecting Neisseria gonorrhoeae in non-US Food and Drug Administration-approved specimen types This test is not intended for use in medico-legal applications.
CHRTI - Overview: Chromosome Analysis, Skin Biopsy
Diagnosis of mosaic congenital chromosome abnormalities, including mosaic aneuploidy and mosaic structural abnormalities Subsequent chromosome analysis when results from peripheral blood are inconclusive
OPE - Overview: Ova and Parasite, Travel History or Immunocompromised, Feces
Detecting and identifying parasitic protozoa and eggs and larvae of parasitic helminths in stool specimens
MMAGP - Overview: Methylmalonic Aciduria Gene Panel, Varies
Follow up for abnormal biochemical results suggestive of a methylmalonic acidemia (MMA) Establishing a molecular diagnosis for patients with MMA Identifying variants within genes known to be associated with MMA, allowing for predictive...
POWVS - Overview: Powassan Virus, RNA, Molecular Detection, PCR, Serum
Rapid testing for Powassan virus RNA (lineage 1 and lineage 2) using serum specimens An adjunctive test to serology for detection of early Powassan virus infection (ie, first few days after symptom onset) This assay should not be used for...
POWVC - Overview: Powassan Virus, RNA, Molecular Detection, PCR, Spinal Fluid
Rapid testing for Powassan virus RNA (lineage 1 and lineage 2) using cerebrospinal fluid specimens An adjunctive test to serology for detection of early Powassan virus infection (ie, first few days after symptom onset) This assay should...
POWVB - Overview: Powassan Virus, RNA, Molecular Detection, PCR, Blood
Rapid testing for Powassan virus RNA (lineage 1 and lineage 2) using whole blood specimens An adjunctive test to serology for detection of early Powassan virus infection (ie, first few days after symptom onset) This assay should not be...
PST - Overview: Protein S Antigen, Total, Plasma
Aiding in the investigation of patients with a history of thrombosis
PYR - Overview: Pyruvic Acid, Blood
Screening for possible disorders of mitochondrial metabolism, when used in conjunction with blood lactate collected at the same time, to determine the lactate-to-pyruvate ratio
TOXGP - Overview: Toxoplasma gondii Antibody, IgG, Serum
Determining whether a patient has had previous exposure to or recent infection with Toxoplasma gondii This test is not useful for diagnosing infection in infants younger than 6 months of age. In that age group, IgG antibodies usually are...
TPRPD - Overview: ThinPrep Diagnostic, Varies
Detecting cervical carcinoma or intraepithelial lesions when screening women for possible cervical neoplasia
TFEBF - Overview: Renal Cell Carcinoma, 6p21.1 (TFEB) Rearrangement, FISH, Tissue
Identifying TFEB gene rearrangements in patients with renal cell carcinoma (RCC)
SFX - Overview: Protein S Activity, Plasma
Second-order testing for diagnosis of congenital or acquired protein S deficiency, ie, as an adjunct to initial testing based on results of protein S antigen assay (free protein S antigen, with or without total protein S antigen assay)...
2425D - Overview: 25-Hydroxyvitamin D:24,25-Dihydroxyvitamin D Ratio, Serum
As a screening test for inactivating CYP24A1 variants in patients with symptoms, signs, or biochemical findings of parathyroid hormone-independent hypercalcemia or hypercalciuria
HBNTP - Overview: Hepatitis B Virus Surface Antigen Confirmation, Prenatal, Serum
Diagnosis of acute, recent, or chronic hepatitis B in prenatal patients This test is not useful during the "window period" of acute hepatitis B (ie, after disappearance of hepatitis B virus surface antigen [HBsAg] and prior to appearance...
IMMG - Overview: Immunoglobulins (IgG, IgA, and IgM), Serum
Detecting or monitoring of monoclonal gammopathies and immune deficiencies
IGA - Overview: Immunoglobulin A (IgA), Serum
Detection or monitoring of IgA monoclonal gammopathies and IgA-related immune deficiencies
ATTF - Overview: Antithrombin Activity, Plasma
Diagnosis of antithrombin deficiency, acquired or congenital Monitoring treatment of antithrombin deficiency disorders, including infusion of antithrombin therapeutic concentrate
ADAMP - Overview: ADAMTS13 Activity with Reflex Inhibitor Profile, Plasma
Assisting with the diagnosis of immune or acquired thrombotic thrombocytopenic purpura
AL - Overview: Aluminum, Serum
Preferred monitoring for aluminum toxicity in patients undergoing dialysis Preferred test for routine aluminum screening Monitoring metallic prosthetic implant wear
LADV - Overview: Adenovirus, Molecular Detection, PCR, Varies
Aiding in the diagnosis of adenovirus infections
MCRNA - Overview: Chlamydia trachomatis, Miscellaneous Sites, Nucleic Acid Amplification, Varies
Detecting Chlamydia trachomatis in non-US Food and Drug Administration-approved specimen types This test is not intended for use in medico-legal applications. This test is not useful for the detection of Chlamydia pneumoniae or other...
MHRP - Overview: Metamycoplasma hominis, Molecular Detection, PCR, Varies
Rapid, sensitive, and specific identification of Metamycoplasma hominis from synovial fluid, genitourinary, reproductive, lower respiratory sources, pleural/chest fluid, pericardial fluid, and wound specimens This test is not intended for...
Diagnosing infections due to Mycoplasma (Mycoplasmoides) pneumoniae Assessing macrolide susceptibility
RMPQU - Overview: Monoclonal Protein Quantitation, Random, Urine
Identifying monoclonal gammopathies using random urine specimens
PNYG - Overview: Phenytoin, Total and Phenobarbital Group, Serum
Monitoring for appropriate therapeutic concentration of phenytoin and phenobarbital Assessing compliance or toxicity
STRC - Overview: Standard Renal Clearance, Plasma and Random Urine
Precise measurement of glomerular filtration rate and renal plasma flow
MPU - Overview: Monoclonal Protein Studies, 24 Hour, Urine
Monitoring patients with monoclonal gammopathies
RMPU - Overview: Monoclonal Protein Studies, Random, Urine
Identifying monoclonal gammopathies using random urine specimens
MBLF - Overview: Mannan Binding Lectin Complement Pathway, Functional, Serum
Investigating recurrent meningococcal disease in young children Investigating recurrent or severe infections in adults Investigating glomerular kidney diseases Additionally, deficiencies or dysregulation within the complement system may...
SMPU - Overview: Monoclonal Protein Screen, 24 Hour, Urine
Monitoring patients with monoclonal gammopathies
STSH - Overview: Thyroid-Stimulating Hormone-Sensitive (s-TSH), Serum
Screening for thyroid dysfunction and detecting mild (subclinical), as well as overt, primary hypo- or hyperthyroidism in ambulatory patients Monitoring patients on thyroid replacement therapy Confirmation of thyrotropin (TSH, formerly...
TGOGF - Overview: TGFBR3 (1p22), OGA (10q24) Rearrangement, FISH, Tissue
Supporting the diagnosis of pleomorphic hyalinizing angiectatic tumor, or hemosiderotic fibrolipomatous tumors associated with rearrangement of the OGA and/or TGFBR3 gene when used in conjunction with an anatomic pathology consultation
TOSU - Overview: Targeted Opioid Screen, Random, Urine
Determining compliance or identifying illicit opioid drug use using urine specimens This test is not intended for employment-related testing.
SEMB - Overview: Semen Analysis with Strict Morphology, Semen
Determining male fertility status Selecting the most cost-effective therapy for treating male-factor infertility Quantifying the number of germinal and white blood cells per milliliter of semen
CDIF - Overview: Clostridioides difficile Culture, Varies
Providing an isolate suitable for antimicrobial susceptibility testing
CRANR - Overview: Cortisol, Free, Random, Urine
Investigating suspected hypercortisolism when a 24-hour collection is prohibitive (ie, pediatric patients)
CHIKC - Overview: Chikungunya Virus, PCR, Molecular Detection, Spinal Fluid
Qualitative detection of chikungunya virus in cerebrospinal fluid after early symptom onset (ideally <7 days) This test is not recommended for screening healthy patients.
CHIKS - Overview: Chikungunya Virus, PCR, Molecular Detection, Serum
Qualitative detection of chikungunya virus in serum after early symptom onset (ideally <7 days) This test is not recommended for screening healthy patients.
2B6Q - Overview: Cytochrome P450 2B6 Genotype, Varies
Aiding in determining therapeutic strategies for drugs that are metabolized by cytochrome P450 (CYP) 2B6 Providing information relevant to bupropion, efavirenz, ketamine, methadone, and nevirapine, as well as other medications metabolized...
DTABS - Overview: Diphtheria/Tetanus Antibody Panel, Serum
Assessing antibody response to tetanus and diphtheria toxoid vaccines, which should be performed at least 3 weeks after immunization Aiding in the evaluation of immunodeficiency This test should not be used to diagnose tetanus infection
STL - Overview: Enteric Pathogens Culture, Feces
Determining whether a bacterial enteric pathogen is the cause of diarrhea May be helpful in identifying the source of the infectious agent (eg, dairy products, poultry, water, or meat) This test is generally not useful for patients...
EBVQN - Overview: Epstein-Barr Virus DNA Detection and Quantification, Plasma
Diagnosis of Epstein-Barr virus (EBV)-associated infectious mononucleosis in individuals with equivocal or discordant EBV serologic marker test results Diagnosis of post-transplant lymphoproliferative disorders (PTLD), especially in...
RPR18 - Overview: Respiratory Profile, Region 18, Alaska, Serum
Assessing sensitization to various inhalant allergens commonly found in Alaska Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or anaphylactic episode -To...
TLCU - Overview: Immunoglobulin Total Light Chains, Urine
Monitoring patients whose urine demonstrates large M-spikes Confirming the quantitation of specimens that show M-spikes by electrophoresis Detecting urine monoclonal proteins and identification of specimens that need urine protein...
POWVU - Overview: Powassan Virus, RNA, Molecular Detection, PCR, Random, Urine
Rapid testing for Powassan virus RNA (lineage 1 and lineage 2) using random urine specimens An adjunctive test to serology for detection of early Powassan virus infection (ie, first few days after symptom onset). This assay should not...
IMTF - Overview: Inflammatory Myofibroblastic Tumors (IMT), 2p23 (ALK) Rearrangement, FISH, Tissue
Supporting the diagnosis of inflammatory myofibroblastic tumors when used conjunction with an anatomic pathology consultation
STRNG - Overview: Strongyloides Antibody, IgG, Serum
Screening for the presence of IgG-class antibodies to Strongyloides This test is not useful for monitoring patient response to therapy as IgG-class antibodies to Strongyloides may remain detectable following resolution of infection.
DSM5X - Overview: Drugs of Abuse Screen 5, Chain of Custody, Meconium
Identifying amphetamines (and methamphetamines), opiates, and phencyclidine, as well as metabolites of cocaine and marijuana in meconium specimens Chain of custody is required whenever the results of testing could be used in a court of...
Hypersensitivity Testing and Initial Patient Management Algorithm 1. Saag M, Balu R, Phillips E, et al. High sensitivity of human leukocyte antigen-b*5701......
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G U ID E D ’EXPÉD ITIO N IN TERN ATIO N ALEENVOYER DES TESTS À LA MAYO CLINIC DEPUIS LE MONDE ENTIER 2 | GUIDE D’EXPÉDITION INTERNATIONALE TABLE DES MATIÈRES EXPÉDIER AUX ÉTATS-UNIS DEPUIS LE MONDE ENTIER 3 Avant...
Pediatric neuro-oncology informative cases - Insights
Neuro-oncology is a complex field undergoing rapid changes with the advancement and evolution of sophisticated genetic testing. Evidence continues to grow in support of broad molecular and cytogenetic analysis for patients with brain...
The diagnosis of Myeloproliferative Neoplasm (MPN) must include an integrated approach and combine the clinical findings with laboratory results. In our latest “Hot Topic,” Rong He, M.D., discusses the subclassification of MPNs and the use...
MCL Autoimmune Axonal Neuropathy A Comprehensive Testing Approach MC2775425
MCL Autoimmune Axonal Neuropathy Comprehensive Testing Approach NEUROLOGY AUTOIMMUNE AXONAL NEUROPATHY COMPREHENSIVE TESTING APPROACH Patients neuropathy variable sensory motor disturbance loss exaggerated