Determination of T-cell clonality in T-cell neoplasms
TRPTS - Overview: Tryptase Immunostain, Technical Component Only
A marker of mast cells
P40NA - Overview: p40 + Napsin A Immunostain, Technical Component Only
p40 aids in the classification of carcinomas and lymphomas Napsin A aids in the identification of primary lung adenocarcinoma
Detection of acute hepatitis C virus (HCV) infection before the appearance of HCV antibodies in serum (ie, <2 months from exposure) Detection and confirmation of chronic HCV infection Quantification of HCV RNA in serum of patients with...
LCAF - Overview: Lung Cancer, ALK (2p23) Rearrangement, FISH, Tissue
Identifying patients with non-small cell lung carcinoma who may benefit from treatment with directed tyrosine kinase inhibitors
AFOLR - Overview: Folate Receptor Alpha (FOLR1), Semi-Quantitative Immunohistochemistry, Manual
Diagnosis of epithelial ovarian cancer that may be eligible for treatment with an anti-folate receptor 1 protein antibody
NEGCT - Overview: Negative Control, Technical Component Only
Qualitative detection of protein expression within cells in paraffin-embedded tissues
EOSDF - Overview: Chronic Eosinophilia, Diagnostic FISH, Varies
Detecting a neoplastic clone associated with the common chromosome abnormalities seen in patients with myeloid/lymphoid neoplasms with eosinophilia and gene rearrangement (including PDGFRA, PDGFRB, FGFR1, JAK2, and ABL1). Supporting the...
NENZ - Overview: Red Blood Cell Enzyme Disorders Gene Panel, Next-Generation Sequencing, Varies
Providing a comprehensive genetic evaluation for patients with a personal or family history suggestive of an underlying red blood cell enzymopathy Identifying variants within genes associated with phenotypic severity, allowing for...
ARBI - Overview: Acetylcholine Receptor (Muscle AChR) Binding Antibody, Serum
Supporting the diagnosis of autoimmune myasthenia gravis (MG) in adults and children Distinguishing autoimmune from congenital MG in adults and children or other acquired forms of neuromuscular junction transmission disorders An adjunct...
CDPCR - Overview: Clostridioides difficile Toxin, PCR, Feces
Sensitive, specific, and rapid diagnosis of Clostridioides (Clostridium) difficile-associated diarrhea and pseudomembranous colitis The test is not recommended as a test of cure.
IFBA - Overview: Intrinsic Factor Blocking Antibody, Serum
Confirming the diagnosis of pernicious anemia
LLPT - Overview: Leukemia/Lymphoma Immunophenotyping, Flow Cytometry, Tissue
Evaluation of tissues for potential involvement by: -Chronic lymphoproliferative disorders -Malignant lymphomas -Acute lymphoblastic leukemia -Acute myelogenous leukemia
Providing a genetic evaluation for patients with a personal or family history suggestive of recessive congenital methemoglobinemia Genotype confirmation of borderline cytochrome b5 reductase (methemoglobin reductase: METR) enzyme activity...
Monitoring response to therapy in patients with chronic myeloid leukemia who are known to have the e13/a2 or e14/a2 BCR/ABL1 fusion transcript forms
PEE - Overview: Porphyrins Evaluation, Whole Blood
Establishing a biochemical diagnosis of erythropoietic protoporphyria and X-linked dominant protoporphyria
FGFR2 - Overview: FGFR2 (10q26.1) Rearrangement, FISH, Tissue
Providing prognostic information and guiding treatment for patients with cholangiocarcinomas and other tumor types including bladder, thyroid, oral cavity, and brain
CMV by PCR
HLHGP - Overview: Primary Hemophagocytic Lymphohistiocytosis Gene Panel, Varies
Providing a comprehensive genetic evaluation for patients with a personal or family history suggestive of familial hemophagocytic lymphohistiocytosis (F-HLH) Establishing a diagnosis of F-HLH, allowing for appropriate management and...
ALFP - Overview: Alpha-Fetoprotein (AFP) Immunostain, Technical Component Only
Aiding in the identification of yolk sac tumors and hepatocellular carcinoma
ANNEX - Overview: Annexin-1 Immunostain, Technical Component Only
Classification of leukemias
BCL6 - Overview: BCL-6 Immunostain, Technical Component Only
Classification of lymphomas
BAMY - Overview: Beta-Amyloid Immunostain, Technical Component Only
Identification of senile plaques in neurodegenerative disease
CD7 - Overview: CD7 Immunostain, Technical Component Only
Identification of T cells and natural killer cells
CXC13 - Overview: CXCL13 Immunostain, Technical Component Only
Assessment of CXCL13 (CXC motif chemokine ligand 13) expression
CDX2 - Overview: CDX2 Immunostain, Technical Component Only
Identification of carcinoma of intestinal origin
CD15 - Overview: CD15 Immunostain, Technical Component Only
Phenotyping leukemias and lymphomas
CALNN - Overview: Calretinin Immunostain, Technical Component Only
Separating mesotheliomas from carcinomas which usually lack expression of calretinin
CD22I - Overview: CD22 Immunostain, Technical Component Only
Determining B-cell lineage
HPL - Overview: Human Placental Lactogen Immunostain, Technical Component Only
Aids in the identification of placenta-related tumors
FUSI - Overview: FUS Immunostain, Technical Component Only
Identification of frontotemporal lobar dementia
ECAD - Overview: E-Cadherin Immunostain, Technical Component Only
Differentiation between lobular and ductal neoplasms of the breast
KRASW - Overview: KRAS Somatic Mutation Analysis, Peritoneal Fluid
Staging of the pancreatic ductal adenocarcinoma(1)
IRF8 - Overview: Interferon Regulatory Factor 8 (IRF8) Immunostain, Technical Component Only
Identification of monoblasts in acute monoblastic/monocytic leukemia and chronic myelomonocytic leukemia
SEMA3 - Overview: Semaphorin 3B (SEMA3B) Immunostain, Technical Component Only
Aiding in the diagnosis of semaphorin 3B-associated membranous nephropathy
MITF - Overview: MiTF Immunostain, Technical Component Only
Identification of melanomas
OTP - Overview: Orthopedia Homeobox Protein (OTP) Immunostain, Technical Component Only
Distinguishing lung carcinoid tumors from metastatic neuroendocrine tumors
THYR - Overview: Thyroglobulin Immunostain, Technical Component Only
Classification of thyroid carcinoma
BTB46 - Overview: ZBTB46 Immunostain, Technical Component Only
Identification of dendritic cells and classification of histiocytic disorders
YAP1 - Overview: Yes-Associated Protein (YAP) Immunostain, Technical Component Only
Identification and differentiation of medulloblastomas
TAU4 - Overview: TAU 4 Immunostain, Technical Component Only
Diagnosis of neurodegenerative disorders
TAU3 - Overview: TAU 3 Immunostain, Technical Component Only
Diagnosis of neurodegenerative disorders
CD21 - Overview: CD21 Immunostain, Technical Component Only
Identification of follicular dendritic cells and a subset of mantle zone lymphocytes
PAX5 - Overview: PAX-5 Immunostain, Technical Component Only
Classification of lymphomas
D240 - Overview: Podoplanin (D2-D40) Immunostain, Technical Component Only
Aids in the identification of reactive follicular dendritic cells
CD43 - Overview: CD43 Immunostain, Technical Component Only
Identification of T lymphocytes, monocytes, macrophages, granulocytes, plasma cells, and a subset of B lymphocytes
TCL1A - Overview: T-Cell Leukemia/Lymphoma Protein 1A (TCL1A) Immunostain, Technical Component Only
Identification of T-cell leukemia and lymphoma protein overexpression in neoplasms
UPII - Overview: Uroplakin II Immunostain, Technical Component Only
Characterization of urothelial carcinoma
MGB - Overview: Mammaglobin (MGB) Immunostain, Technical Component Only
Breast-specific marker Aids in evaluating tumors of unknown primary site
ACTHI - Overview: Adrenocorticotropic Hormone (ACTH) Immunostain, Technical Component Only
Aiding in the classification of pituitary adenomas and neoplasms with ectopic hormone production
Since the pandemic hit, she's spent a great deal of time vetting antibody tests and has set up a COVID-19 testing program at Mayo Clinic....
Staffing to Workload in Phlebotomy Areas: Off-Site Operational Needs - Insights
discusses staffing to workload in phlebotomy areas with a focus on off-site operational needs, including paid time off and unpaid time off....
practices from the program, Mayo Medical Laboratories collaborated with National Decision Support Company (NDSC) to combine Mayo’s clinical knowledge with NDSC’s industry-leading expertise in electronic...
Laboratory and pathology research roundup: August 30 - Insights
This week's research roundup features: Kidney biopsy chronicity grading in antineutrophil cytoplasmic antibody-associated vasculitis...
Visit Mayo Clinic Laboratories at the APA Annual Meeting - Insights
Visit Mayo Clinic Laboratories at booth #2047 to learn about our comprehensive therapeutics test offerings. Developed by board-certified experts in clinical chemistry, molecular, and toxicology testing...