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GQ1ES - Overview: Ganglioside GQ1b Antibody, IgG, ELISA, Serum

Evaluating patients with an underlying demyelinating neuropathy Supporting the diagnosis of a ganglioside GQ1b IgG-related disorder

PBCU - Overview: Lead/Creatinine Ratio, Urine

Detecting clinically significant lead exposure using random urine specimens This test is not a substitute for blood lead screening.

LPSBF - Overview: Lipase, Body Fluid

Determining whether pancreatic inflammation or pancreatic fistula may be contributing to a pathological accumulation of fluid

MPHNU - Overview: Methylphenidate and Metabolite, Random, Urine

Monitoring urine methylphenidate and ritalinic acid concentrations to assess compliance in patients

LEFLU - Overview: Leflunomide Metabolite (Teriflunomide), Serum

Therapeutic monitoring of patients actively taking leflunomide Assessment of elimination in patients requiring enhanced elimination of the drug

AC1Q - Overview: Anti-C1q Antibodies, IgG, Serum

Evaluating patients with suspected anti-C1q vasculitis Predicting renal involvement in patients with systemic lupus erythematosus Detection of anti-C1q antibodies in serum

AMIO - Overview: Amiodarone, Serum

Monitoring amiodarone therapy, especially when amiodarone is coadministered with other drugs that may interact Evaluating possible amiodarone toxicity Assessing patient compliance

A_CR - Overview: Albumin/Creatinine Ratio

Calculating the albumin concentration per creatinine Assessing the potential for early onset of nephropathy in diabetic patients using random urine specimens

BUPM - Overview: Buprenorphine and Norbuprenorphine, Random, Urine

Monitoring of compliance utilizing buprenorphine Detection and confirmation of the illicit use of buprenorphine

F_11 - Overview: Coagulation Factor XI Activity Assay, Plasma

Diagnosing deficiency of coagulation factor XI Investigating prolonged activated partial thromboplastin time

MGS - Overview: Magnesium, Serum

Monitoring preeclampsia patients being treated with magnesium sulfate, although in most cases monitoring clinical signs (respiratory rate and deep tendon reflexes) is adequate and blood magnesium levels are not required

SULFU - Overview: Sulfate, 24 Hour, Urine

Assessing the nutrition intake of animal protein The calculation of urinary supersaturation of various crystals or stones

TBGI - Overview: Thyroxine-Binding Globulin (TBG), Serum

Cases in which total thyroid hormone levels do not correlate with the thyrometabolic status, most commonly with pregnancy or the use of contraceptive steroids

CUU - Overview: Copper, 24 Hour, Urine

Investigation of Wilson disease and obstructive liver disease using a 24-hour urine specimen

CDTA - Overview: Carbohydrate Deficient Transferrin, Adult, Serum

Indicating chronic alcohol abuse This test is not appropriate for screening patients for congenital disorders of glycosylation.

CL_F - Overview: Chloride, Feces

Workup of cases of chronic diarrhea Evaluation of suspected chloridorrhea

CEA - Overview: Carcinoembryonic Antigen (CEA), Serum

Monitoring colorectal cancer and selected other cancers such as medullary thyroid carcinoma May be useful in assessing the effectiveness of chemotherapy or radiation treatment This test is not useful for screening the general population...

CHIKG - Overview: Chikungunya IgG, Antibody, Serum

Aiding in the diagnosis of recent infection with Chikungunya virus detecting IgG antibodies in patients with recent travel to endemic areas and a compatible clinical syndrome

CALC5 - Overview: Calcium, Random, Urine

Measurement of calcium for the evaluation of calcium oxalate and calcium phosphate kidney stone risk, and calculation of urinary supersaturations Evaluation of bone diseases, including osteoporosis and osteomalacia

CHIKM - Overview: Chikungunya IgM, Antibody, Serum

Aiding in the diagnosis of recent infection with Chikungunya virus detecting IgM antibodies in patients with recent travel to endemic areas and a compatible clinical syndrome

F9_IS - Overview: Factor IX Inhibitor Screen, Plasma

Detecting the presence of a specific factor inhibitor directed against coagulation factor IX

GALCR - Overview: Galactocerebrosidase Reflex, Leukocytes

Diagnosis of Krabbe disease as a confirmatory reflex of the six-enzyme panel Follow-up testing for evaluation of an abnormal newborn screening result for Krabbe disease This test is not recommended for carrier detection because of the...

PNPAB - Overview: Paraneoplastic Pemphigus Antibody, IgG, Serum

Diagnosis of paraneoplastic pemphigus/paraneoplastic autoimmune multiorgan syndrome in the setting of erosive or lichenoid mucocutaneous disease

CALX - Overview: CALR Mutation Analysis, Myeloproliferative Neoplasm (MPN), Reflex, Varies

Aiding in the distinction between a reactive cytosis and a chronic myeloproliferative disorder Evaluating mutations in CALR in an algorithmic process for the MPNR / Myeloproliferative Neoplasm, JAK2 V617F with Reflex to CALR and MPL,...

F_10 - Overview: Coagulation Factor X Activity Assay, Plasma

Diagnosing deficiency of coagulation factor X, congenital or acquired Evaluating hemostatic function in liver disease Investigation of prolonged prothrombin time or activated partial thromboplastin time

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In this month’s “Hot Topic,” Elitza Theel, Ph.D., will discuss the detection of (1→3)-β-D-glucan (BDG) in serum as a biomarker for the presence of invasive fungal infections....

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Week in Review: March 3 - Insights

Today's Highlights Include: COVID-19 deaths remain low compared to previous winters, FDA authorizing first at-home combo flu/Covid test, and Rochester public schools evaluating mental health needs and services throughout the district.