E157C - Overview: Escherichia coli O157:H7 Culture, Feces

Determining whether Escherichia coli O157:H7 may be the cause of diarrhea Reflexive testing for Shiga toxin and/or E coli O157:H7 nucleic acid amplification test-positive feces This test is generally not useful for patients hospitalized...

MPS4B - Overview: Mucopolysaccharidosis IV Enzyme Panel, Blood Spot

Supporting the biochemical diagnosis of mucopolysaccharidosis type IVA and IVB This test is not useful for carrier detection.

FCFS - Overview: Caspofungin Susceptibility Testing

Caspofungin Susceptibility Testing

FISST - Overview: Isavuconazole Susceptibility Testing

Isavuconazole Susceptibility Testing

FITZS - Overview: Itraconazole Susceptibility Testing

Itraconazole Susceptibility Testing

FVOST - Overview: Voriconazole Susceptibility Testing

Voriconazole Susceptibility Testing

SAT - Overview: Percent Saturation

Calculation of percent saturation

CL_F - Overview: Chloride, Feces

Workup of cases of chronic diarrhea Evaluation of suspected chloridorrhea

ALC - Overview: Ethanol, Blood

Detection of ethanol (ethyl alcohol) in blood to document prior consumption or administration of ethanol Quantification of the concentration of ethanol in blood correlates directly with degree of intoxication This test is not intended for...

MSDBS - Overview: Multiple Sulfatase Deficiency, Blood Spot

Supporting the biochemical diagnosis of multiple sulfatase deficiency This test is not useful for carrier detection.

TYRBS - Overview: Tyrosinemia Follow Up Panel, Blood Spot

Monitoring of individuals with tyrosinemia type 1 (HT-1) Diagnosis of HT-1 when used in conjunction with testing for urine organic acids, liver function, alpha-fetoprotein, and molecular genetic analysis of the fumarylacetoacetate...

GNANG - Overview: Hereditary Angioedema Focused Gene Panel, Next-Generation Sequencing, Varies

Evaluating hereditary angioedema (HAE) with normal C1 inhibitor (C1INH) in patients with a suggestive personal or family history Confirming a diagnosis of HAE with normal C1INH with the identification of a known or suspected...

GMCSF - Overview: Granulocyte Monocyte-Colony Stimulating Factor, Plasma

Measuring the concentration of granulocyte macrophage-colony stimulating factor (GM-CSF) in plasma Understanding the etiology of chronic inflammatory diseases or infections, when used in conjunction with clinical information and other...

VIBC - Overview: Vibrio Culture, Feces

Determining whether Vibrio species may be the cause of diarrhea This test is generally not useful for patients that have been hospitalized for more than 3 days because the yield from these patients' specimens is very low, as is the...

CRMTC - Overview: Collapsin Response-Mediator Protein-5 (CRMP-5) Neuronal IgG Titer, Spinal Fluid

Evaluation of neuroautoimmunity, particularly small-cell lung carcinoma and thymoma, in conjunction with other antineuronal antibodies Reporting an end titer result from cerebrospinal fluid specimens

MGMTD - Overview: MGMT Promoter Methylation Analysis, Tumor

Prognostication of newly diagnosed patients with glioblastoma Identification of newly diagnosed glioblastoma patients that may derive benefit from alkylating chemotherapy (ie, temozolomide) Therapy selection for newly diagnosed...

CARNU - Overview: Carnitine, Random, Urine

Evaluation of patients with a clinical suspicion of a wide range of conditions including organic acidemias and fatty acid oxidation disorders Monitoring carnitine treatment

WNDZ - Overview: Wilson Disease, ATP7B Full Gene Sequencing with Deletion/Duplication, Varies

Confirming the diagnosis of Wilson disease

IDENT - Overview: Organism Referred for Identification, Aerobic Bacteria

Identification of pure isolates of aerobic bacteria Differentiation of members of the Staphylococcus aureus complex (S aureus, Staphylococcus argenteus, Staphylococcus schweitzeri)

SHIGC - Overview: Shigella Culture, Feces

Determining whether Shigella species may be the cause of diarrhea Reflexive testing for Shigella species from nucleic acid amplification test-positive stool This test is generally not useful for patients hospitalized more than 3 days...

CARBI - Overview: Carbapenem Resistance Genes, Molecular Detection, PCR, Varies

Detecting and differentiating blaKPC, blaNDM, blaVIM, blaOXA-48, and blaIMP gene sequences associated with carbapenem intermediate or resistant results Aiding in infection control in the detection of gastrointestinal colonization of...

BUPMX - Overview: Buprenorphine and Norbuprenorphine, Chain of Custody, Random, Urine

Monitoring of compliance of buprenorphine therapy Detection and confirmation of the illicit use of buprenorphine Chain of custody is required whenever the results of testing could be used in a court of law. Its purpose is to protect the...

CHAGI - Overview: Trypanosoma cruzi, Technical Interpretation

Diagnosis of chronic Trypanosoma cruzi infection (Chagas disease)

CBBRP - Overview: Coxiella burnetii (Q fever), Molecular Detection, PCR, Blood

Aiding in the diagnosis of Coxiella burnetii infection (eg, Q fever)

ALCX - Overview: Ethanol, Chain of Custody, Blood

Detection of ethanol (ethyl alcohol) in blood to document prior consumption or administration of ethanol Quantification of the concentration of ethanol in blood correlates directly with degree of intoxication All testing is performed...

GALTP - Overview: Galactose-1-Phosphate Uridyltransferase Biochemical Phenotyping, Erythrocytes

Determining the biochemical phenotype for galactosemia when enzymatic and molecular results are incongruent

FAO - Overview: Fatty Acid Oxidation Probe Assay, Fibroblast Culture

In vitro confirmation of biochemical diagnoses of the following fatty acid oxidation disorders: -Short-chain acyl-CoA dehydrogenase deficiency -Medium-chain acyl-CoA dehydrogenase deficiency -Long-chain 3-hydroxyacyl-CoA dehydrogenase...

MMAGP - Overview: Methylmalonic Aciduria Gene Panel, Varies

Follow up for abnormal biochemical results suggestive of a methylmalonic acidemia (MMA) Establishing a molecular diagnosis for patients with MMA Identifying variants within genes known to be associated with MMA, allowing for predictive...

PBDV - Overview: Lead, Venous, with Demographics, Blood

Detecting lead toxicity in venous blood specimens

PBDC - Overview: Lead, Capillary, with Demographics, Blood

Detecting lead toxicity with capillary collections

VWACT - Overview: von Willebrand Factor Activity, Plasma

Diagnosis of von Willebrand disease (VWD) and differentiation of VWD subtypes or differentiation of VWD from hemophilia A Monitoring therapeutic efficacy of treatment with DDAVP (desmopressin) or VWF concentrates in patients with VWD

HSMBS - Overview: Hepatosplenomegaly Panel, Blood Spot

As a component of the initial evaluation of a patient presenting with hepatosplenomegaly, using dried blood spot specimens This test is not useful for the identification of carriers. This test should not be used as a monitoring tool for...

HPP12 - Overview: HIV-1/HIV-2 RNA Detection Prenatal, Plasma

Diagnosis of HIV-1 and/or HIV-2 infection in pregnant individuals with indeterminate or inconclusive HIV serologic test results Diagnosis of HIV-1 and/or HIV-2 infection in pregnant individuals in the acute or early phase of HIV-1 and/or...

CTXBS - Overview: Cerebrotendinous Xanthomatosis, Blood Spot

Evaluating patients with a clinical suspicion of cerebrotendinous xanthomatosis (CTX) using dried blood spot specimens Monitoring individuals with CTX on chenodeoxycholic acid (CDCA) therapy This test is not useful for the...

NSAI - Overview: Neurosyphilis IgG, Antibody Index, Spinal Fluid

Aid in the diagnosis of neuroinvasive syphilis as part of a profile

QFT4 - Overview: QuantiFERON-TB Gold Plus, Blood

Indirect test for Mycobacterium tuberculosis infection, to be used in conjunction with risk assessment, radiography, and other medical and diagnostic evaluations This test is not recommended for use for diagnosis of active tuberculosis...

WASEQ - Overview: Alpha Globin Gene Sequencing, Varies

Diagnosing nondeletional alpha thalassemia Testing for nondeletional alpha thalassemia in a symptomatic individual Follow-up testing to an abnormal hemoglobin electrophoresis that identified an alpha-globin chain variant

PDGP - Overview: Peroxisomal Disorder Gene Panel, Varies

Follow up of abnormal biochemical result, usually very long-chain fatty acid test consistent with peroxisomal disorder Establishing a molecular diagnosis for patients with peroxisomal disorders Identifying variants within genes known to...

IL1B - Overview: Interleukin-1 Beta, Plasma

Measuring the concentration of interleukin-1 beta in plasma Evaluating patients experiencing inflammatory conditions, autoinflammatory disorders, and infection

EVROL - Overview: Everolimus, Blood

Managing everolimus immunosuppression in solid organ transplant

FL - Overview: Fluoride, Plasma

Assessing accidental fluoride ingestion Monitoring patients receiving sodium fluoride for bone disease or patients receiving voriconazole therapy

SPNC - Overview: Streptococcus pneumoniae Antigen, Spinal Fluid

Rapid diagnosis of pneumococcal meningitis

MSUSC - Overview: Branched-Chain Amino Acids, Self-Collect, Blood Spot

Monitoring patients with maple syrup urine disease using specimens collected at home

LNBAI - Overview: Lyme Central Nervous System Infection IgG, Antibody Index, Spinal Fluid

Providing antibody index information to aid in the diagnosis of neuroinvasive Lyme disease or neuroborreliosis due to Borrelia species associated with Lyme disease (eg, Borrelia burgdorferi, Borrelia garinii, Borrelia afzelli)

HEXBZ - Overview: Sandhoff Disease, HEXB Gene, Full Gene Analysis, Varies

Follow up for abnormal biochemical results suggestive of Sandhoff disease Establishing a molecular diagnosis for patients with Sandhoff disease Identifying variants within genes known to be associated with Sandhoff disease, allowing for...

HPRP - Overview: Helicobacter pylori with Clarithromycin Resistance Prediction, Molecular Detection, PCR, Tissue

Aiding in the diagnosis of Helicobacter pylori infection and prediction of clarithromycin resistance or susceptibility directly from gastric biopsies

HPFRP - Overview: Helicobacter pylori with Clarithromycin Resistance Prediction, Molecular Detection, PCR, Feces

Aiding in the diagnosis of Helicobacter pylori infection and prediction of clarithromycin resistance or susceptibility directly from stool

ML1HM - Overview: MLH1 Hypermethylation Analysis, Tumor

An adjunct to TMSI / Microsatellite Instability, Tumor and IHC / Mismatch Repair (MMR) Protein Immunohistochemistry Only, Tumor when colon or endometrial tumor demonstrates microsatellite instability (MSI-H) and loss of MLH1 protein...

CCFR - Overview: Cortisol/Cortisone, Free, Random, Urine

Investigating suspected Cushing syndrome (hypercortisolism), when a 24-hour collection is prohibitive (ie, pediatric patients) Assisting in diagnosing acquired or inherited abnormalities of 11-beta-hydroxy steroid dehydrogenase (cortisol...

NSESF - Overview: Neuron-Specific Enolase (NSE), Spinal Fluid

An auxiliary test in the diagnosis of Creutzfeldt-Jakob disease An auxiliary test in the diagnosis of small cell lung carcinoma metastasis to central nervous system or leptomeninges