NFLP - Overview: Neurofilament Light Chain, Plasma
Assessing neuronal damage related to various neurodegenerative diseases
EOSDF - Overview: Chronic Eosinophilia, Diagnostic FISH, Varies
Detecting a neoplastic clone associated with the common chromosome abnormalities seen in patients with myeloid/lymphoid neoplasms with eosinophilia and gene rearrangement (including PDGFRA, PDGFRB, FGFR1, JAK2, and ABL1). Supporting the...
CASRG - Overview: CASR Full Gene Sequencing with Deletion/Duplication, Varies
Providing a genetic evaluation of individuals with a personal or family history of familial hypocalciuric hypercalcemia, neonatal severe primary hyperparathyroidism, or autosomal dominant hypoparathyroidism (autosomal dominant...
NMS1 - Overview: Necrotizing Myopathy Evaluation, Serum
Evaluating patients with suspected necrotizing autoimmune myopathy
CMPRG - Overview: Family Member Comparator Specimen for Genome Sequencing, Varies
Submitting a biological family member's specimen to be used as a comparator for affected patients (probands) undergoing whole genome sequencing
Simultaneous detection and differentiation of SARS-CoV-2 (cause of COVID-19), influenza A virus, influenza B virus, and respiratory syncytial virus in upper or lower respiratory tract specimens from individuals with flu-like illnesses
NONCM - Overview: Neuro-Oncology Gene Panel, Mutations Only, Tumor
Identifying mutations that may support a diagnosis or help determine prognosis for patients with central nervous system tumors Identifying specific mutations within genes known to be associated with response or resistance to specific...
VWACT - Overview: von Willebrand Factor Activity, Plasma
Diagnosis of von Willebrand disease (VWD) and differentiation of VWD subtypes or differentiation of VWD from hemophilia A Monitoring therapeutic efficacy of treatment with DDAVP (desmopressin) or VWF concentrates in patients with VWD
SCAP - Overview: Spinocerebellar Ataxia Repeat Expansion Panel, Varies
Molecular confirmation of clinically suspected spinocerebellar ataxia when a specific subtype isn't suspected
CTP10 - Overview: Catecholamine Fractionation, Standing, Plasma, Free
Diagnosis of pheochromocytoma and paraganglioma in specimens collected from individuals in a standing position, as an auxiliary test to fractionated plasma and urine metanephrine measurements Diagnosis and follow-up of patients with...
PSF - Overview: Protein S Antigen, Free, Plasma
As part of an investigation of patients with a history of thrombosis
RPR5 - Overview: Respiratory Profile, Region 5, Ohio Valley (IN, KY, OH, TN, WV), Serum
Assessing sensitization to various inhalant allergens commonly found in the Ohio Valley region including Indiana, Kentucky, Ohio, Tennessee, and West Virginia Defining the allergen responsible for eliciting signs and symptoms...
IFG23 - Overview: Intact Fibroblast Growth Factor 23, Serum
Diagnosing and monitoring tumor induced osteomalacia Diagnosing X-linked hypophosphatemia or autosomal dominant hypophosphatemic rickets Diagnosing familial tumoral calcinosis with hyperphosphatemia
PBORB - Overview: Lyme Disease, Molecular Detection, PCR, Blood
Supporting the diagnosis of Lyme disease in conjunction with serologic testing This test should not be used to screen asymptomatic patients.
Risk stratification of patients with treated multiple myeloma, which can assist in determining treatment and management decisions Risk stratification of patients with newly diagnosed multiple myeloma
CLLMF - Overview: Chronic Lymphocytic Leukemia, Specified FISH, Varies
Detecting recurrent common chromosome abnormalities in patients with chronic lymphocytic leukemia (CLL) Distinguishing patients with 11;14 translocations who have the leukemic phase of mantle cell lymphoma from patients who have CLL...
Monitoring acute (ie, short-term) drug use in addiction treatment or pain management settings as part of a rotational drug testing strategy Presumptive screening for amphetamine, methamphetamine, opioids/opiates (targeting morphine,...
KCSF - Overview: Immunoglobulin Kappa Free Light Chain, Spinal Fluid
Diagnosing multiple sclerosis and other demyelinating conditions Evaluating patients who present with a clinically isolated syndrome in which the patient reports symptoms (headaches, optic neuritis, fatigue, and many others, depending on...
CTP0 - Overview: Catecholamine Fractionation, Supine, Plasma, Free
Diagnosis of pheochromocytoma and paraganglioma in specimens collected from individuals in a supine position, as an auxiliary test to fractionated plasma and urine metanephrine measurements Diagnosis and follow-up of patients with...
VZGM - Overview: Varicella-Zoster Antibody, IgM and IgG, Serum
Laboratory diagnosis of acute and recent infection with varicella-zoster virus (VZV) Determination of immune status of individuals to the VZV Documentation of previous infection with VZV in an individual without a previous record of...
CFX - Overview: Protein C Activity, Plasma
As an initial test for evaluating patients suspected of having congenital protein C deficiency, including those with personal or family histories of thrombotic events Detecting and confirming congenital type I and type II protein C...
BRCMG - Overview: Brucella Antibody Screen, IgM and IgG, ELISA, Serum
Evaluating patients with suspected brucellosis
NPM1Q - Overview: Nucleophosmin (NPM1) Mutation Analysis, Varies
As a prognostic indicator in patients with newly diagnosed acute myelogenous leukemia with normal karyotype and no FLT3 variant and as a leukemia-specific marker of minimal residual disease
ML1HM - Overview: MLH1 Hypermethylation Analysis, Tumor
An adjunct to TMSI / Microsatellite Instability, Tumor and IHC / Mismatch Repair (MMR) Protein Immunohistochemistry Only, Tumor when colon or endometrial tumor demonstrates microsatellite instability (MSI-H) and loss of MLH1 protein...
PBNP1 - Overview: NT-Pro B-Type Natriuretic Peptide, Serum
Aiding in the diagnosis of congestive heart failure using serum specimens
STSH - Overview: Thyroid-Stimulating Hormone-Sensitive (s-TSH), Serum
Screening for thyroid dysfunction and detecting mild (subclinical), as well as overt, primary hypo- or hyperthyroidism in ambulatory patients Monitoring patients on thyroid replacement therapy Confirmation of thyrotropin (TSH, formerly...
CDIF - Overview: Clostridioides difficile Culture, Varies
Providing an isolate suitable for antimicrobial susceptibility testing
CLFA - Overview: Cryptococcus Antigen Screen with Titer, Spinal Fluid
Aiding in the diagnosis of cryptococcosis This test should not be performed as a screening procedure for the general population. This test should not be used as a test of cure or to guide treatment decisions.
DHEA_ - Overview: Dehydroepiandrosterone (DHEA), Serum
Diagnosing and differential diagnosis of hyperandrogenism (in conjunction with measurements of other sex steroids) As an initial screen in adults with bioavailable testosterone measurement that may be supplemented with measurements of sex...
GPSYP - Overview: Glucopsychosine, Plasma
Second-tier test when newborn screening results with reduced beta-glucosidase (GBA) activity are identified Diagnosis and monitoring of patients with Gaucher disease using plasma specimens Supporting a biochemical diagnosis of Gaucher...
OPATU - Overview: Opiates Confirmation, Random, Urine
Detection and quantification of codeine, hydrocodone, oxycodone, morphine, hydromorphone, oxymorphone, noroxycodone, noroxymorphone, norhydrocodone, dihydrocodeine, and naloxone in urine
PSA - Overview: Prostate-Specific Antigen (PSA) Diagnostic, Serum
As an aid in the detection of prostate cancer when used in conjunction with a digital rectal exam in men 50 years and older To aid in the prognosis and management of individuals diagnosed with prostate cancer
TOXB - Overview: Toxoplasma gondii, Molecular Detection, PCR, Blood
Supporting the diagnosis of active toxoplasmosis, particularly in immunocompromised individuals
MANN - Overview: Alpha-Mannosidase, Leukocytes
Diagnosis of alpha-mannosidosis This test is not useful for establishing carrier status for alpha-mannosidosis.
VRERP - Overview: Vancomycin-Resistant Enterococcus, Molecular Detection, PCR, Varies
Identifying carriers of vancomycin-resistant enterococci
VMAR - Overview: Vanillylmandelic Acid, Random, Urine
Screening children for catecholamine-secreting tumors using a random urine collection when requesting vanillylmandelic acid only Supporting a diagnosis of neuroblastoma Monitoring patients with a treated neuroblastoma
TIU24 - Overview: Titanium, 24 Hour, Urine
Monitoring exposure and elimination of titanium in a 24-hour urine specimen
VIBC - Overview: Vibrio Culture, Feces
Determining whether Vibrio species may be the cause of diarrhea This test is generally not useful for patients that have been hospitalized for more than 3 days because the yield from these patients' specimens is very low, as is the...
PIPA - Overview: Pipecolic Acid, Serum
Differentiating between disorders of peroxisomal biogenesis (eg, Zellweger syndrome) and disorders with loss of a single peroxisomal function Detecting abnormal elevations of pipecolic acid in serum
CARFT - Overview: Carbamazepine, Free and Total, Serum
Monitoring carbamazepine (free and total) therapy in patients who are uremic
TIWB - Overview: Titanium, Blood
Detecting and monitoring titanium exposure and potential implant status in patients with orthopedic implants
HRTVS - Overview: Heartland Virus, RNA, Molecular Detection, PCR, Serum
Aiding in the diagnosis of central nervous system infection caused by Heartland virus using serum specimens
HEVM - Overview: Hepatitis E Virus IgM Antibody Screen with Reflex to Confirmation, Serum
Diagnosis of acute or recent (<6 months) hepatitis E infection
LALB - Overview: Lysosomal Acid Lipase, Blood
Evaluation of patients with a clinical presentation suggestive of lysosomal acid lipase deficiency using blood specimens This test is not useful to determine carrier status for cholesteryl ester storage disease or Wolman disease.
KKRP - Overview: Kingella kingae, Molecular Detection, PCR, Varies
Aiding in the diagnosis of Kingella kingae infection using tissue or synovial fluid specimens
KIDST - Overview: Kidney Stone Analysis
Managing patients with recurrent renal calculi (kidney stones)
MRDMR - Overview: Multiple Myeloma Minimal Residual Disease by Flow Cytometry, Bone Marrow
Detecting low level (minimal residual disease) myeloma cells after therapy to confirm remission has been achieved
FUCW - Overview: Alpha-Fucosidase, Leukocytes
Detection of fucosidosis This test is not useful for establishing carrier status for fucosidosis.
APIXA - Overview: Apixaban, Anti-Xa, Plasma
Measuring apixaban concentration in selected clinical situations (eg, renal insufficiency, assessment of compliance, periprocedural measurement of drug concentration, suspected overdose, advanced age, and extremes of body weight)
ALBR - Overview: Albumin, Random, Urine
Assessing the potential for early onset of nephropathy in diabetic patients using random urine specimens
NELL-1 [Test in Focus] - Insights
D., discusses how Mayo Clinic Laboratories’ new immunohistochemistry test for the detection of NELL-1 antigen, a biomarker for membranous nephropathy found in 10% to 15% of patients, provides diagnostic...
Looking Back on Clinical Chemistry 1 - Insights
in the Mayo Clinic Medical Laboratory Science program, takes a look back on her Clinical Chemistry 1 course....
Mayo Clinic Ranked No. 1 Hospital Nationwide by U.S. News & World Report - Insights
Report’s 29th annual "Best Hospitals Honor Roll" published online on August 14. Mayo Clinic also ranked No. 1 in more specialties than any other hospital in the country....
Orexin-A/Hypocretin-1 for the Diagnosis of Type 1 Narcolepsy [Test in Focus] - Insights
test to perform as well as to interpret. The orexin-A/hypocretin-1 test is a sensitive and specific alternative to the MSLT to diagnose type 1 narcolepsy....
Week in Review: November 1 - Insights
Top highlights include: Facebook launches into the digital space of healthcare, medical breakthrough for Ebola, and how the brain makes memories.