TSCP - Overview: Tuberous Sclerosis Gene Panel, Varies
Establishing a molecular diagnosis in individuals with features of tuberous sclerosis complex (TSC). Identifying pathogenic variants within the TSC1 and TSC2 genes known to be associated with TSC, allowing for predictive testing of at-risk...
VIRID - Overview: Viral Susceptibility, Defects in Intrinsic and Innate Immunity, Gene Panel, Varies
Providing a comprehensive genetic evaluation for patients with a personal or family history suggestive of an inborn error of immunity causing a hereditary form of severe viral susceptibility Establishing a diagnosis of hereditary form of...
UCDP - Overview: Urea Cycle Disorders Gene Panel, Varies
Follow up for abnormal biochemical results suggestive of a urea cycle disorder (UCD) Establishing a molecular diagnosis for patients with a UCD Identifying variants within genes known to be associated with UCD, allowing for predictive...
GSDGP - Overview: Glycogen Storage Disease Gene Panel, Varies
Follow up of abnormal biochemical results consistent with glycogen storage disease (GSD) Establishing a molecular diagnosis for patients with GSD Identifying variants within genes known to be associated with GSD allowing for predictive...
MSUDP - Overview: Maple Syrup Urine Disease Gene Panel, Varies
Follow up for abnormal biochemical results suggestive of maple syrup urine disease (MSUD) Establishing a molecular diagnosis for patients with MSUD Identifying variants within genes known to be associated with MSUD, allowing for...
TIKLB - Overview: Tick-Borne Panel, Molecular Detection, PCR, Blood
Evaluating patients with suspected human monocytic ehrlichiosis, human granulocytic anaplasmosis, babesiosis, or Borrelia miyamotoi infection Evaluating patients with a history of, or suspected, tick exposure who are presenting with...
HIAAP - Overview: 5-Hydroxyindoleacetic Acid, Plasma
Biochemical diagnosis and monitoring of intestinal carcinoid syndrome using a plasma specimen
THYR - Overview: Thyroglobulin Immunostain, Technical Component Only
Classification of thyroid carcinoma
6MAMU - Overview: 6-Monoacetylmorphine Confirmation, Random, Urine
Determination of heroin use
VANPA - Overview: Vancomycin, Peak, Serum
Monitoring peak levels in selected patients receiving vancomycin therapy
URCU - Overview: Uric Acid, 24 Hour, Urine
Assessment and management of patients with kidney stones, particularly uric acid stones
MA2EC - Overview: Ma2 Antibody, ELISA, Spinal Fluid
Evaluating patients with suspected paraneoplastic encephalitides using spinal fluid specimens
PCAB - Overview: Parietal Cell Antibodies, IgG, Serum
Evaluating patients suspected of having pernicious anemia or autoimmune-mediated deficiency of vitamin B12 with or without megaloblastic anemia
CYCPK - Overview: Cyclosporine, Peak, Blood
Monitoring whole blood peak cyclosporine concentration during therapy, particularly in individuals coadministered cytochrome P450 (CYP) 3A4 substrates, inhibitors, or inducers Adjusting dose to optimize immunosuppression while minimizing...
TOPI - Overview: Topiramate, Serum
Monitoring serum concentrations of topiramate Assessing compliance Assessing potential toxicity
GQ1ES - Overview: Ganglioside GQ1b Antibody, IgG, ELISA, Serum
Evaluating patients with an underlying demyelinating neuropathy Supporting the diagnosis of a ganglioside GQ1b IgG-related disorder
IGGS4 - Overview: IgG4, Immunoglobulin Subclasses, Serum
Supporting the diagnosis of IgG4-related disease
INS - Overview: Insulin, Serum
Diagnosing insulinoma, when used in conjunction with proinsulin and C-peptide measurements Management of diabetes mellitus
AMPHU - Overview: Amphetamines Confirmation, Random, Urine
Confirming drug exposure involving amphetamines such as amphetamine and methamphetamine, phentermine, pseudoephedrine/ephedrine, methylenedioxyamphetamine (MDA), and methylenedioxymethamphetamine (MDMA)
AMS - Overview: Amylase, Total, Serum
Diagnosis and management of pancreatitis Evaluation of pancreatic function
BRUTA - Overview: Brucella Total Antibody Confirmation, Agglutination, Serum
Diagnosis of brucellosis
CYSR - Overview: Cystinuria Profile, Quantitative, Random, Urine
Biochemical diagnosis of cystinuria using random urine specimens
CYSPR - Overview: Cyclosporine, Blood
Monitoring whole blood cyclosporine concentration during therapy, particularly in individuals coadministered cytochrome P450 (CYP) 3A4 substrates, inhibitors, or inducers Adjusting dose to optimize immunosuppression while minimizing...
MUC - Overview: Mucor, IgE, Serum
Establishing a diagnosis of an allergy to mucor Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or anaphylactic episode -To confirm sensitization prior to...
OSM24 - Overview: Osmolality, 24 Hour, Urine
Assessing the concentrating and diluting ability of the kidney using a 24-hour urine collection
PLA2I - Overview: Phospholipase A2 Receptor, Immunofluorescence, Serum
Distinguishing primary from secondary membranous nephropathy in patients with low levels of anti-phospholipase A2 receptor (PLA2R) antibodies Screening for anti-PLA2R antibodies Monitoring patients with membranous nephropathy at very...
SEMA3 - Overview: Semaphorin 3B (SEMA3B) Immunostain, Technical Component Only
Aiding in the diagnosis of semaphorin 3B-associated membranous nephropathy
MSTC1 - Overview: Strict Criteria Sperm Morphology for Infertility Diagnosis and Treatment, Semen
Diagnosing male infertility Selecting the most cost-effective therapy for treating male-factor infertility Quantifying the number of germinal and WBCs per mL of semen
Interpretation for the evaluation of stiff-person spectrum disorders, including the classical or focal forms, such as stiff-limb or stiff-trunk, and progressive encephalomyelitis with rigidity and myoclonus, using spinal fluid specimens
Interpretation for the evaluation of stiff-person spectrum disorders including the classical or focal forms, such as stiff-limb or stiff-trunk, and progressive encephalomyelitis with rigidity and myoclonus, using serum specimens
TRYPP - Overview: Tryptophan, Plasma
Investigating inadequate tryptophan intake and monitoring dietary treatment
CAT - Overview: Cat Epithelium, IgE, Serum
Establishing a diagnosis of an allergy to cat epithelium Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or anaphylactic episode -To confirm sensitization...
DATE - Overview: Date, Fruit, IgE, Serum
Establishing the diagnosis of an allergy to date, fruit Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or anaphylactic episode -To confirm sensitization...
CLOBZ - Overview: Clobazam and Metabolite, Serum
Monitoring clobazam therapy
CLOM - Overview: Clomipramine, Serum
Determining whether a poor therapeutic response is attributable to noncompliance Monitoring serum concentration of clomipramine and norclomipramine to assist in optimizing the administered dose
THCU - Overview: Delta-8 and Delta-9-Carboxy-Tetrahydrocannabinol (THC) Confirmation, Random, Urine
Detection and confirmation of drug use of cannabis/marijuana and to specifically identify and quantify delta-8-carboxy tetrahydrocannabinol (THC-COOH) and delta-9-THC-COOH
MMPM - Overview: Mumps Virus Antibody, IgM, Serum
Laboratory diagnosis of mumps virus infection
VANTA - Overview: Vancomycin, Trough, Serum
Preferred test for monitoring vancomycin therapy Monitoring trough concentrations drawn at steady-state in selected patients receiving vancomycin therapy
VANRA - Overview: Vancomycin, Random, Serum
Monitoring adequacy of drug concentration during vancomycin therapy whenever a specimen is submitted or collected without collection timing information
AMH1 - Overview: Antimullerian Hormone, Serum
Assessing ovarian status, including ovarian reserve and responsiveness, as part of an evaluation for infertility and assisted reproduction protocols Assessment of menopausal status, including premature ovarian failure Evaluation of...
Diagnosis of inflammatory demyelinating diseases (IDD) with similar phenotype to neuromyelitis optica (NMO) spectrum disorder (NMOSD), including optic neuritis (single or bilateral) and transverse myelitis Diagnosis of autoimmune myelin...
SCCA - Overview: Squamous Cell Carcinoma Antigen, Serum
Aiding in the evaluation and monitoring of squamous cell carcinoma of the head and neck, lung, and cervix This test should not be used to screen for carcinoma or other disorders including those of the liver, lung, or skin.
TLYM - Overview: T-Cell Lymphoma, FISH, Tissue
Detecting common, recurrent chromosome abnormalities in various T-cell lymphomas in paraffin-embedded tissue specimens at diagnosis Providing prognostic information in patients with documented systemic ALK-negative anaplastic large cell...
SOD1Z - Overview: SOD1 Gene, Full Gene Analysis, Varies
Establishing a molecular diagnosis for patients with amyotrophic lateral sclerosis (ALS) Identifying variants within SOD1 known to be associated with ALS, allowing for predictive testing of at-risk family members
EOSMF - Overview: Chronic Eosinophilia, Specified FISH, Varies
Detecting a neoplastic clone associated with the common chromosome abnormalities seen in patients with myeloid/lymphoid neoplasms with eosinophilia and gene rearrangement (including PDGFRA, PDGFRB, FGFR1, JAK2, and ABL1) using specified...
CHIMU - Overview: Chimerism Transplant No Cell Sort, Varies
Determining the relative amounts of donor and recipient cells in a specimen An indicator of bone marrow transplant success
SLL - Overview: Small Lymphocytic Lymphoma, FISH, Tissue
Recurrent common chromosome abnormalities in patients with small lymphocytic lymphoma (SLL) Distinguishing patients with 11;14 translocations who have mantle cell lymphoma (MCL) from patients who have SLL Detecting patients with atypical...
MCLNR - Overview: MayoComplete Lung Rearrangements, Rapid Test, Tumor
Identifying lung tumors that may respond to targeted therapies by simultaneously assessing multiple genes involved in rearrangements resulting in fusion transcripts Diagnosing and managing patients with lung cancer
Identifying MDM2 amplification Supporting the diagnosis of many neoplasms, including, but not limited to, well-differentiated liposarcoma, atypical lipomatous tumor, dedifferentiated liposarcoma, parosteal osteosarcoma and central...
RAVMP - Overview: Ravulizumab Monitoring Panel, Serum
Monitoring of complement blockage by ravulizumab Assessing the response to ravulizumab therapy Assessing the need for dose escalation Evaluating the potential for dose deescalation or discontinuation of therapy in remission...
NELL-1 [Test in Focus] - Insights
D., discusses how Mayo Clinic Laboratories’ new immunohistochemistry test for the detection of NELL-1 antigen, a biomarker for membranous nephropathy found in 10% to 15% of patients, provides diagnostic...
Looking Back on Clinical Chemistry 1 - Insights
in the Mayo Clinic Medical Laboratory Science program, takes a look back on her Clinical Chemistry 1 course....
Mayo Clinic Ranked No. 1 Hospital Nationwide by U.S. News & World Report - Insights
Report’s 29th annual "Best Hospitals Honor Roll" published online on August 14. Mayo Clinic also ranked No. 1 in more specialties than any other hospital in the country....
Orexin-A/Hypocretin-1 for the Diagnosis of Type 1 Narcolepsy [Test in Focus] - Insights
test to perform as well as to interpret. The orexin-A/hypocretin-1 test is a sensitive and specific alternative to the MSLT to diagnose type 1 narcolepsy....
Week in Review: November 1 - Insights
Top highlights include: Facebook launches into the digital space of healthcare, medical breakthrough for Ebola, and how the brain makes memories.