NKX3 - Overview: NKX3.1 Immunostain, Technical Component Only
Identifying tumors of prostatic origin
NFSMI - Overview: Neurofilament (SMI31) Immunostain, Technical Component Only
Differentiating neurons (neurofilament positive) from glia (neurofilament negative)
NCSRY - Overview: Nicotine Survey, Serum
Monitoring tobacco use in a health fair setting
PFIB - Overview: Parafibromin, Immunostain, Technical Component Only
Parafibromin, Immunostain, Technical Component Only
MEF2B - Overview: Myocyte Enhancer Factor 2 (MEF2B) Immunostain, Technical Component Only
Lymphoma classification
MOC31 - Overview: MOC-31 Immunostain, Technical Component Only
Marker of epithelial cells
HBME - Overview: Mesothelial Cell (HBME-1) Immunostain, Technical Component Only
Classification of thyroid carcinomas
NEUN - Overview: Neu-N Immunostain, Technical Component Only
Identification of neuronal nuclei
TRPS - Overview: Troponin T, 5th Generation, Plasma
Aiding in the exclusion of the diagnosis of acute coronary syndrome in a single plasma specimen Aiding in the diagnosis of acute coronary syndrome Monitoring acute coronary syndromes and estimating prognosis Possible utility in...
SATB2 - Overview: SATB2 Immunostain, Technical Component Only
Identification of colorectal carcinoma and rectal neuroendocrine tumors
Thyroid transcription factor 1aids in the classification of carcinomas of unknown origin Keratin 5 aids in the identification of squamous cell carcinoma
SSX18 - Overview: Synovial Sarcoma Panel, Technical Component Only
Aiding in distinguishing synovial sarcomas from similar sarcomas
SMAD4 - Overview: SMAD4 Immunostain, Technical Component Only
Identification of loss of SMAD4 (mothers against decapentaplegic homolog 4 drosophila) expression within pancreatic ductal adenocarcinoma
CYSQN - Overview: Cystinuria Profile, Quantitative, 24 Hour, Urine
Diagnosis of cystinuria using 24-hour urine collections
CEAPT - Overview: Carcinoembryonic Antigen (CEA), Peritoneal Fluid
An adjunct to cytology to differentiate between malignancy-related and benign causes of ascites formation
CDUCR - Overview: Cadmium/Creatinine Ratio, Random, Urine
Detecting exposure to cadmium, a toxic heavy metal, using random urine specimens
FXCH - Overview: Coagulation Factor X Chromogenic Activity Assay, Plasma
Monitoring warfarin anticoagulant therapy, especially in patients whose plasma contains lupus anticoagulants that interfere with baseline prothrombin time/international normalized ratio and in patients receiving the drug Argatroban who are...
CD123 - Overview: CD123 Immunostain, Technical Component Only
Marker of plasmacytoid monocytes, mast cells, and megakaryocytes
CD138 - Overview: CD138 (Syndecan) Immunostain, Technical Component Only
Marker of plasma cells and squamous epithelial cells
PGM1 - Overview: CD68 (PG-M1) Immunostain, Technical Component Only
Identification of monocytic differentiation Phenotyping hematolymphoid neoplasms that are suspected to represent histiocytic sarcomas
CD8I - Overview: CD8 Immunostain, Technical Component Only
Identification of cytotoxic T cells
CMET - Overview: cMET Immunostain, Technical Component Only
Identification of normal and neoplastic c-Met expressing cells
CERS - Overview: Ceruloplasmin, Serum
Investigation of patients with possible Wilson disease
Aids in the diagnosis of epithelioid hemangioendotheliomas
CALCI - Overview: Calcitonin (CALCI) Immunostain, Technical Component Only
Aids in the identification of C cells of thyroid, medullary thyroid carcinomas, many atypical laryngeal carcinoids, and other neuroendocrine tumors
CARF - Overview: Carbamazepine, Free, Serum
Monitoring unbound or free carbamazepine levels in patients where the total carbamazepine result is within the therapeutic range, but the patient is experiencing side effects Monitoring carbamazepine (free) therapy in patients who are...
CACR3 - Overview: Calcium/Creatinine Ratio, Random, Urine
Evaluation of calcium oxalate and calcium phosphate kidney stone risk Calculation of urinary supersaturation Evaluation of bone diseases, including osteoporosis and osteomalacia
CD14I - Overview: CD14 Immunostain, Technical Component Only
Marker of histiocytic and monocytic lineage and follicular dendritic cells
CEAPC - Overview: Carcinoembryonic Antigen (CEA), Pancreatic Cyst Fluid
When used in conjunction with imaging studies, cytology, and other pancreatic cyst fluid tumor markers: -Distinguishing between mucinous and nonmucinous pancreatic cysts -Determining the likely type of malignant pancreatic cyst
DEXT - Overview: Dermatopathology Consultation, Wet Tissue
Histologic diagnosis and differential diagnosis of cutaneous diseases
DESG3 - Overview: Desmoglein 3 (DSG3) Immunostain, Technical Component Only
Classification of squamous cell carcinomas
CASF - Overview: IgG/Albumin Ratio, Spinal Fluid
Assessment of cerebrospinal fluid (CSF) IgG/albumin ratio in the absence of a paired CSF and serum specimen
TB2LN - Overview: Susceptibility, Mycobacterium tuberculosis Complex, Second Line, Varies
Determination of Mycobacterium tuberculosis complex minimal inhibitory concentrations to second-line antimicrobial agents
CIMT - Overview: Coccidioides immitis/posadasii, Molecular Detection, PCR, Paraffin, Tissue
Rapid detection of Coccidioides DNA Aiding in the diagnosis of coccidioidomycosis using paraffin-embedded tissue specimens
HK36M - Overview: Histone H3 K36M Mutant (H3F3 K36M) Immunostain, Technical Component Only
Diagnosis of chondroblastoma
GLUTS - Overview: Glutamine Synthetase Immunostain, Technical Component Only
Classification of hepatic adenomas and the identification of focal nodular hyperplasia
TIA1 - Overview: T-Cell Intracellular Antigen 1 (TIA-1) Immunostain, Technical Component Only
Characterizing neoplasms of cytotoxic T cells or natural killer cells
TRPTS - Overview: Tryptase Immunostain, Technical Component Only
A marker of mast cells
TTF40 - Overview: TTF41 (SPT24) + p40 Immunostain, Technical Component Only
Thyroid transcription factor 1 aids in the classification of carcinomas of unknown origin p40 aids in the classification of carcinomas and lymphomas
CD163 - Overview: CD163 Immunostain, Technical Component Only
Identification of cells of monocytic/histiocytic lineage, expressed late in maturation
C3FX - Overview: C3 Complement, Functional, Serum
Diagnosis of C3 deficiency Investigation of a patient with undetectable total complement level
C5FX - Overview: C5 Complement, Functional, Serum
Diagnosis of C5 deficiency Investigation of a patient with an undetectable total complement level
C8FX - Overview: C8 Complement, Functional, Serum
Diagnosis of C8 deficiency Investigation of a patient with an undetectable total hemolytic complement level
C7FX - Overview: C7 Complement, Functional, Serum
Diagnosis of C7 deficiency Investigation of a patient with an undetectable total complement level
FOXP1 - Overview: FOXP1 Immunostain, Technical Component Only
Classification of lymphomas
C6FX - Overview: C6 Complement, Functional, Serum
Diagnosis of C6 deficiency Investigation of a patient with an undetectable total complement level
LANGR - Overview: Langerin Immunostain, Technical Component Only
Visualization of normal and neoplastic Langerhans cells
EIACD - Overview: Clostridioides difficile Toxin, EIA, Feces
Diagnosing the presence of toxigenic Clostridioides difficile
VHLZZ - Overview: Von Hippel Lindau Syndrome, VHL, Full Gene Analysis, Varies
Evaluating patients with a personal or family history suggestive of Von Hippel-Lindau (VHL) syndrome Establishing a diagnosis of a VHL allowing for targeted cancer surveillance based on associated risks Identifying genetic variants...
AHUSD - Overview: Atypical Hemolytic Uremic Syndrome Complement Panel, Serum and Plasma
Detecting deficiencies in the alternative pathway that can cause atypical-hemolytic uremic syndrome, dense deposit disease, and C3 glomerulonephritis A second-tier test that aids in the differential diagnosis of thrombotic...
helps in diagnosis, treatment, and prognosis of ALS and MS - Insights
neurofilament light chain (Nfl) proteins in blood, clinicians can better diagnose devastating diseases like ALS and MS, help predict disease progression, and better assess efficacy of existing drugs and trial therapies...
Frontotemporal dementia and ALS - Insights
Learn more about how detection of amyotrophic lateral sclerosis and frontotemporal dementia paved the way for gene-targeted therapies for patients.
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1939: Lou Gehrig Comes to Mayo Clinic #ThrowbackThursday - Insights
June 1939, his name became associated with an illness called amyotrophic lateral sclerosis (ALS). Today, ALS is known as Lou Gehrig’s Disease....
Hereditary Alzheimer's disease and dementia - Insights
Learn about our genetic testing for Alzheimer’s disease, amyotrophic lateral sclerosis (ALS), frontotemporal dementia, and CADASIL....