SCTF - Overview: Sex Chromosome Determination, FISH, Tissue
Identifying the sex chromosome complement in paraffin-embedded tissues
MBLF - Overview: Mannan Binding Lectin Complement Pathway, Functional, Serum
Investigating recurrent meningococcal disease in young children Investigating recurrent or severe infections in adults Investigating glomerular kidney diseases Additionally, deficiencies or dysregulation within the complement system may...
SZMON - Overview: Sezary Monitoring Flow Cytometry, Blood
Monitoring response to therapy in patients with previously diagnosed Sezary syndrome or mycosis fungoides
CRMTS - Overview: Collapsin Response-Mediator Protein-5 (CRMP-5) Neuronal IgG Titer, Serum
Evaluation of neurological autoimmunity particularly that associated with small-cell lung carcinoma and thymoma Reporting an end titer result from serum specimens
CDGN - Overview: Congenital Disorders of N-Glycosylation, Serum
Screening for N-linked congenital disorders of glycosylation Providing information on specific structural oligosaccharide abnormalities to potentially direct further genetic testing
CRANR - Overview: Cortisol, Free, Random, Urine
Investigating suspected hypercortisolism when a 24-hour collection is prohibitive (ie, pediatric patients)
RPR18 - Overview: Respiratory Profile, Region 18, Alaska, Serum
Assessing sensitization to various inhalant allergens commonly found in Alaska Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or anaphylactic episode -To...
TALDO - Overview: Polyols, Quantitative, Urine
Diagnosing deficiencies of transaldolase, transketolase, sedoheptulose, or ribose-5-phosphate isomerase
FGGMC - Overview: Toxoplasma gondii Antibodies (IgG, IgM), ELISA, CSF
Toxoplasma gondii Antibodies (IgG, IgM), ELISA, CSF
GlycoMark
GNF11 - Overview: Hemophilia C (Factor XI Deficiency), F11 Gene, Next-Generation Sequencing, Varies
Evaluating factor XI deficiency (FXID) in patients with a personal or family history suggestive of FXID Confirming an FXID diagnosis with the identification of known or suspected disease-causing alterations in the F11 gene Determining...
CDGGP - Overview: Congenital Disorders of Glycosylation Gene Panel, Varies
Establishing a molecular diagnosis for patients with congenital disorders of glycosylation Identifying variants within genes known to be associated with congenital disorders of glycosylation, allowing for predictive testing of at-risk...
B6PA - Overview: Pyridoxic Acid, Plasma
Determining the concentration of pyridoxic acid in the assessment of vitamin B6 status
TYROS - Overview: Tyrosinase (TYROS) Immunostain, Technical Component Only
Aiding in the identification of normal melanocytes and malignant melanoma
Diagnosing fat malabsorption due to pancreatic or intestinal disorders Monitoring effectiveness of enzyme supplementation in certain malabsorption disorders This test is not useful for differentiating among pancreatic diseases.
RBR - Overview: Retinol-Binding Protein, Random, Urine
Assessing renal tubular injury or dysfunction using random urine collections Screening for other tubular abnormalities Detecting chronic asymptomatic renal tubular dysfunction.(2)
GAL2 - Overview: Probability of Hepatocellular Carcinoma, Serum
Calculation of the risk for patients with chronic liver disease to develop hepatocellular carcinoma
CDKP1 - Overview: CD68 (KP1) Immunostain, Tissue, Technical Component Only
Aiding in the identification of histocytic and myeloid lineage cells
SEAS - Overview: Seasonal Inhalants Allergen Profile, Serum
Establishing a diagnosis of an allergy to seasonal inhalants Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or anaphylactic episode -To confirm...
P63 - Overview: p63 Immunostain, Technical Component Only
Aiding in identifying squamous, urothelial, or myoepithelial differentiation in tumors
SORD - Overview: Sorbitol and Xylitol, Quantitative, Random, Urine
Screening for sorbitol dehydrogenase deficiency-related neuropathy
WEEPC - Overview: Western Equine Encephalitis Antibody Panel, IgG and IgM, Spinal Fluid
Aiding in the diagnosis of Western equine encephalitis using spinal fluid specimens
SMAT - Overview: Smooth Muscle Antibody Titer, Serum
Antibody titer testing as a part of the evaluation of patients with hepatitis of unknown origin associated with hypergammaglobulinemia and/or abnormal liver enzymes
HEMMF - Overview: Hematologic Specified FISH, Varies
The detection of specific chromosomal abnormalities in hematologic malignancies
HEVG - Overview: Hepatitis E Virus IgG Antibody, Serum
Diagnosis of past exposure to hepatitis E virus
HEG1 - Overview: HEG1 Immunostain, Technical Component Only
Diagnosis of epithelioid mesothelioma versus non-small cell carcinoma
GBM - Overview: Glomerular Basement Membrane Antibodies, IgG, Serum
Evaluating patients with clinical features of anti-glomerular basement disease, including rapidly progressive glomerulonephritis or pulmonary hemorrhage
GASTN - Overview: Gastrin Immunostain, Technical Component Only
Characterization of islet cell tumors and endocrine tumors of the gastrointestinal tract
FASC - Overview: Fascin Immunostain, Technical Component Only
Classification of lymphomas
BFOS - Overview: FosB, Immunostain, Technical Component Only
Diagnosing pseudomyogenic (epithelioid sarcoma-like) hemangioendothelioma and epithelioid hemangiomas
3FBLN - Overview: Fibulin 3 Immunostain, Technical Component Only
Identification and classification of amyloid types in tissue
EMICZ - Overview: Emicizumab, Modified One Stage Assay Factor VIII, Plasma
Monitoring compliance or potential development of an antidrug antibody This assay is not indicated for monitoring factor VIII infusions or for making a diagnosis of hemophilia.
PBU - Overview: Lead, 24 Hour, Urine
Detecting clinically significant lead exposure in 24-hour specimens This test is not a substitute for blood lead screening.
LFABP - Overview: Liver Fatty Acid-Binding Protein (L-FABP) Immunostain, Technical Component Only
Classification of hepatic adenomas
UIOD - Overview: Iodine, 24 Hour, Urine
Assessing iodine toxicity or recent exposure in a 24-hour urine collection Monitoring iodine excretion rate as index of replacement therapy
ACHE_ - Overview: Acetylcholinesterase, Amniotic Fluid
Diagnosing open neural tube defects and, to a lesser degree, ventral wall defects
ADMA - Overview: Asymmetric Dimethylarginine, Plasma
Assessing the likelihood of future coronary events in patients with coronary heart disease, type II diabetes mellitus, or kidney disease Prompting intervention and assessing improvements among subjects with elevated ADMA and...
ALKOT - Overview: Anaplastic Lymphoma Kinase (ALK [OTI1A4]) Immunostain, Technical Component Only
Identification of anaplastic lymphoma kinase overexpression Diagnosis of inflammatory myofibroblastic tumor and anaplastic large cell lymphoma
B2MC - Overview: Beta-2-Microglobulin (Beta-2-M), Spinal Fluid
Evaluation of central nervous system inflammation and B-cell proliferative diseases
BILIT - Overview: Bilirubin, Total, Serum
Assessing liver function Evaluating a wide range of diseases affecting the production, uptake, storage, metabolism, or excretion of bilirubin Monitoring the efficacy of neonatal phototherapy
C4U - Overview: C4 Acylcarnitine, Quantitative, Random, Urine
Evaluation of patients with abnormal newborn screens showing elevations of iso-/butyrylcarnitine to aid in the differential diagnosis of short-chain acyl-CoA dehydrogenase and isobutyryl-CoA dehydrogenase deficiencies
C9FX - Overview: C9 Complement, Functional, Serum
Diagnosis of C9 deficiency Investigation of a patient with a low total (hemolytic) complement level
MUSK - Overview: Muscle-Specific Kinase (MuSK) Autoantibody, Serum
Diagnosis of autoimmune muscle-specific kinase (MuSK) myasthenia gravis Second-order test to aid in the diagnosis of autoimmune myasthenia gravis when first-line serologic tests are negative Establishing a quantitative baseline value...
SOMAT - Overview: Somatostatin Immunostain, Technical Component Only
Aids in the characterization of pancreatic islet cell tumors or other neuroendocrine tumors
NEREG - Overview: Northeast Regional Allergen Profile, Serum
Establishing a diagnosis of an allergy to northeast regional allergen profile Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or anaphylactic episode -To...
TACPK - Overview: Tacrolimus, Peak, Blood
Assessment of postdosing (peak) blood tacrolimus concentrations
Aiding in the diagnosis of California (La Crosse) encephalitis using spinal fluid specimens
CARF - Overview: Carbamazepine, Free, Serum
Monitoring unbound or free carbamazepine levels in patients where the total carbamazepine result is within the therapeutic range, but the patient is experiencing side effects Monitoring carbamazepine (free) therapy in patients who are...
CACR3 - Overview: Calcium/Creatinine Ratio, Random, Urine
Evaluation of calcium oxalate and calcium phosphate kidney stone risk Calculation of urinary supersaturation Evaluation of bone diseases, including osteoporosis and osteomalacia
DEXT - Overview: Dermatopathology Consultation, Wet Tissue
Histologic diagnosis and differential diagnosis of cutaneous diseases
NELL-1 [Test in Focus] - Insights
D., discusses how Mayo Clinic Laboratories’ new immunohistochemistry test for the detection of NELL-1 antigen, a biomarker for membranous nephropathy found in 10% to 15% of patients, provides diagnostic...
Looking Back on Clinical Chemistry 1 - Insights
in the Mayo Clinic Medical Laboratory Science program, takes a look back on her Clinical Chemistry 1 course....
Mayo Clinic Ranked No. 1 Hospital Nationwide by U.S. News & World Report - Insights
Report’s 29th annual "Best Hospitals Honor Roll" published online on August 14. Mayo Clinic also ranked No. 1 in more specialties than any other hospital in the country....
Orexin-A/Hypocretin-1 for the Diagnosis of Type 1 Narcolepsy [Test in Focus] - Insights
test to perform as well as to interpret. The orexin-A/hypocretin-1 test is a sensitive and specific alternative to the MSLT to diagnose type 1 narcolepsy....
Week in Review: November 1 - Insights
Top highlights include: Facebook launches into the digital space of healthcare, medical breakthrough for Ebola, and how the brain makes memories.