FRUCT - Overview: Fructosamine, Serum

Monitoring intermediate (1-3 weeks) glycemic control Monitoring glycemic control in patients with shortened red blood cell survival

AGU20 - Overview: Acylglycines, Quantitative, Random, Urine

Diagnosis and monitoring for patients affected with one of the following inborn errors of metabolism: Fatty Acid Oxidation Disorders: -Glutaric acidemia type II -Medium-chain 3-ketoacyl-coenzyme A (CoA) thiolase (MCKAT)...

OPTU - Overview: Orthostatic Protein, Timed Collection, Urine

Diagnosis of orthostatic proteinuria As a second-order test for additional characterization of proteinuria of less than 3 grams/24 hours, particularly in children or adolescents

MPSER - Overview: Mucopolysaccharides Quantitative, Serum

Quantification of dermatan sulfate, heparan sulfate, and keratan sulfate in serum to support the biochemical diagnosis of mucopolysaccharidoses types I, II, III, IV, VI, or VII

MPSWB - Overview: Mucopolysaccharidosis, Blood

Supporting the biochemical diagnosis of mucopolysaccharidoses type I, II, III, IV, or VI Quantification of heparan sulfate, dermatan sulfate, and keratan sulfate in whole blood specimens

MPSBS - Overview: Mucopolysaccharidosis, Blood Spot

Supporting the biochemical diagnosis of mucopolysaccharidoses types I, II, III, IV, or VI Quantification of heparan sulfate, dermatan sulfate, and keratan sulfate in dried blood spot specimens

TTIGS - Overview: Tetanus Toxoid IgG Antibody, Serum

Assessing antibody response to the tetanus toxoid vaccine, which should be performed at least 3 weeks after immunization Aiding in the evaluation of immunodeficiency This test should not be used to diagnose tetanus infection.

PREGN - Overview: Pregnenolone, Serum

An ancillary test for congenital adrenal hyperplasia, particularly in situations in which a diagnosis of both 21- and 11-hydroxylase deficiency have been ruled out Confirming a diagnosis of 3-beta-hydroxy dehydrogenase deficiency

DTABS - Overview: Diphtheria/Tetanus Antibody Panel, Serum

Assessing antibody response to tetanus and diphtheria toxoid vaccines, which should be performed at least 3 weeks after immunization Aiding in the evaluation of immunodeficiency This test should not be used to diagnose tetanus infection

PINS - Overview: Proinsulin, Plasma

As part of the diagnostic workup of suspected insulinoma As part of the diagnostic workup of patients with suspected prohormone convertase 1/3 deficiency As part of the diagnostic workup of patients with suspected proinsulin variations

VIBC - Overview: Vibrio Culture, Feces

Determining whether Vibrio species may be the cause of diarrhea This test is generally not useful for patients that have been hospitalized for more than 3 days because the yield from these patients' specimens is very low, as is the...

AERMC - Overview: Aeromonas Culture, Feces

Determining whether Aeromonas species may be the cause of diarrhea This test is generally not useful for patients hospitalized more than 3 days because the yield from specimens from these patients is very low, as is the likelihood of...

FPHIV - Overview: Phenosense HIV Drug Resistance Replication Capacity

Determines viral phenotype resistance to three classes of commonly prescribed antiretroviral drugs: nucleoside reverse transcriptase inhibitors (NRTI), non-nucleoside reverse transcriptase inhibitors (NNRTI), and protease inhibitors (PI)....

FPGT - Overview: Phenosense Combination HIV Drug Resistance Assay

Determines viral phenotype and genotype resistance to three classes of commonly prescribed antiretroviral drugs: nucleoside reverse transcriptase inhibitors (NRTI), nonnucleoside reverse transcriptase inhibitors (NNRTI), and protease...

CD40 - Overview: B-Cell CD40 Expression by Flow Cytometry, Blood

Evaluating patients for hyper-IgM type 3 (HIGM3) syndrome due to defects in CD40, typically seen in patients less than 10 years Assessing B-cell immune competence in other clinical contexts, including autoimmunity, malignancy, and...

ALDEF - Overview: Alpha Defensin, Lateral Flow Assay, Synovial Fluid

Detection of alpha defensins 1-3, human host response proteins, in synovial fluid of adults with a total joint replacement who are being evaluated for revision surgery This test is not intended to be used to determine timing for...

EAEBV - Overview: Epstein-Barr Virus Early Antigen, IgG, Serum

Diagnosis of Epstein Barr virus (EBV) infectious mononucleosis in cases when heterophile antibody test results are negative and EBV-specific serologic testing is inconclusive Aiding in the diagnosis of type 2 or type 3 nasopharyngeal...

FAPM - Overview: Fatty Acid Profile, Mitochondrial (C8-C18), Serum

Biochemical diagnosis of inborn errors of mitochondrial fatty acid oxidation, including deficiencies of medium-chain acyl-Co-A dehydrogenase, long-chain 3-hydroxyacyl-Co-A dehydrogenase, very long-chain acyl-Co-A dehydrogenase, and glutaric...

AVWPR - Overview: von Willebrand Disease Profile, Plasma

Detection of deficiency or abnormality of von Willebrand factor (VWF) and related deficiency of factor VIII coagulant activity Subtyping von Willebrand disease (VWD) as type 1 (most common), type 2 variants (less common), or type 3...

CAMPC - Overview: Campylobacter Culture, Feces

Determining whether Campylobacter species may be the cause of diarrhea Reflexive testing for Campylobacter species from nucleic acid amplification test-positive feces This test is generally not useful for patients hospitalized more than...

SALMC - Overview: Salmonella Culture, Feces

Determining whether Salmonella species may be the cause of diarrhea Reflexive testing for Salmonella species from nucleic acid amplification test-positive feces This test is generally not useful for patients hospitalized more than 3...

SHIGC - Overview: Shigella Culture, Feces

Determining whether Shigella species may be the cause of diarrhea Reflexive testing for Shigella species from nucleic acid amplification test-positive stool This test is generally not useful for patients hospitalized more than 3 days...

17OHP - Overview: 17-Hydroxypregnenolone, Serum

As an ancillary test for congenital adrenal hyperplasia (CAH), particularly in situations in which a diagnosis of both 21- and 11-hydroxylase deficiency have been ruled out Confirming a diagnosis of 3-beta-hydroxysteroid dehydrogenase...

YERSC - Overview: Yersinia Culture, Feces

Determining whether Yersinia species may be the cause of diarrhea Reflexive testing for Yersinia species from nucleic acid amplification test-positive feces This test is generally not useful for patients hospitalized more than 3 days...

H2MT - Overview: HER2 Amplification, Miscellaneous Tumor, FISH, Tissue

Guiding cancer therapy, as patients with HER2 amplification may be candidates for therapies that target the human epidermal growth factor receptor 2 (HER2) protein (eg, trastuzumab [Herceptin], pertuzumab) Confirming the presence of HER2...

STL - Overview: Enteric Pathogens Culture, Feces

Determining whether a bacterial enteric pathogen is the cause of diarrhea May be helpful in identifying the source of the infectious agent (eg, dairy products, poultry, water, or meat) This test is generally not useful for patients...

STFR - Overview: Soluble Transferrin Receptor (sTfR), Serum

Evaluation of suspected iron deficiency in patients who may have inflammation, infection, or chronic disease and other conditions in which ferritin concentration does not correlate with iron status, including: -Cystic fibrosis patients who...

17PRN - Overview: Pregnenolone and 17-Hydroxypregnenolone, Serum

An ancillary test for congenital adrenal hyperplasia (CAH), particularly in situations in which a diagnosis of both 21- and 11-hydroxylase deficiency have been ruled out Confirming a diagnosis of 3-beta-hydroxysteroid dehydrogenase...

FHLCG - Overview: Immunoglobulin G (IgG) Heavy and Light Chain (HLC) Pairs, Kappa and Lambda with Ratio

Heavy and light chain pair quantitation may be useful for: 1. Distinguishing between broadly migrating monoclonal proteins and restricted polyclonal immunoglobulin patterns on serum electrophoresis. 2. Quantitating monoclonal IgG proteins...

C2729 - Overview: Breast Carcinoma-Associated Antigen, Serum

Aiding in the management of breast cancer in patients with metastatic disease by monitoring the progression or regression of disease in response to treatment Serial testing in women with prior stage II or III breast cancer who are...

E157C - Overview: Escherichia coli O157:H7 Culture, Feces

Determining whether Escherichia coli O157:H7 may be the cause of diarrhea Reflexive testing for Shiga toxin and/or E coli O157:H7 nucleic acid amplification test-positive feces This test is generally not useful for patients hospitalized...

MPO - Overview: Myeloperoxidase Antibodies, IgG, Serum

Evaluating patients with clinical features anti-neutrophil cytoplasmic antibody associated vasculitis, specifically granulomatosis with polyangiitis, microscopic polyangiitis (MPA), and eosinophilic granulomatosis with polyangiitis...

GLIOF - Overview: 1p/19q Deletion in Gliomas, FISH, Tissue

Aids in diagnosing oligodendroglioma tumors and predicting the response of an oligodendroglioma to therapy May be useful in tumors with a complex "hybrid" morphology requiring differentiation from pure astrocytomas to support the presence...

AVWPI - Overview: von Willebrand Disease Profile Technical Interpretation

Technical interpretation of the von Willebrand factor profile test Detection of deficiency or abnormality of von Willebrand factor and related deficiency of factor VIII coagulant activity Subtyping von Willebrand disease (VWD) as type 1...

EBVQN - Overview: Epstein-Barr Virus DNA Detection and Quantification, Plasma

Diagnosis of Epstein-Barr virus (EBV)-associated infectious mononucleosis in individuals with equivocal or discordant EBV serologic marker test results Diagnosis of post-transplant lymphoproliferative disorders (PTLD), especially in...

AVWPQ - Overview: von Willebrand Disease Profile Interpretation

Interpretation of testing performed as part of a profile for detection of deficiency or abnormality of von Willebrand factor (VWF) and related deficiency of factor VIII coagulant activity Interpretation of testing performed as part of a...

H2BR - Overview: HER2 Amplification Associated with Breast Cancer, FISH, Tissue

A predictive marker for patients with both node-positive or node-negative primary and metastatic breast cancer Patients with HER2 amplification that may be candidates for therapies targeting the human epidermal growth factor receptor 2...

APOEG - Overview: Apolipoprotein E Genotyping, Blood

Determining the specific apolipoprotein E (APOE) genotypes in individuals with type III hyperlipoproteinemia Determining the specific APOE genotypes that may increase risk for amyloid related imaging abnormalities in individuals being...

HCVDR - Overview: Hepatitis C Virus Genotypic Antiviral Drug Resistance, Serum

Detecting and identifying codon substitutions in the hepatitis C virus (HCV) NS3, NS5A, and NS5B genomic regions that confer resistance to current direct-acting antiviral drugs used for treatment of chronic hepatitis C infection due to HCV...

FHLCA - Overview: Immunoglobulin A (IgA) Heavy and Light Chain (HLC) Pairs, Kappa and Lambda with Ratio

For the quantitative measurement of human IgA heavy chain and light chain intact immunoglobulin in serum. The result can be used when monitoring previously diagnosed IgA multiple myeloma patients and is used in conjunction with other...

CLPMG - Overview: Phospholipid (Cardiolipin) Antibodies, IgG and IgM, Serum

The following clinical situations: -Unexplained arterial or venous thrombosis -A history of pregnancy morbidity defined as 1 or more unexplained deaths of a morphologically normal fetus beyond the 10th week of gestation, 1 or more premature...

FAO - Overview: Fatty Acid Oxidation Probe Assay, Fibroblast Culture

In vitro confirmation of biochemical diagnoses of the following fatty acid oxidation disorders: -Short-chain acyl-CoA dehydrogenase deficiency -Medium-chain acyl-CoA dehydrogenase deficiency -Long-chain 3-hydroxyacyl-CoA dehydrogenase...

GCLIP - Overview: Phospholipid (Cardiolipin) Antibodies, IgG, Serum

The following clinical situations, when used in conjunction with other criterial antiphospholipid antibody tests: -Unexplained arterial or venous thrombosis -A history of pregnancy morbidity defined as 1 or more unexplained deaths of a...

HCYSS - Overview: Homocysteine, Total, Serum

An aid for screening patients suspected of having an inherited disorder of methionine metabolism including: -Cystathionine beta-synthase deficiency (homocystinuria) -Methylenetetrahydrofolate reductase deficiency and its thermolabile...

HCYSP - Overview: Homocysteine, Total, Plasma

An aid for screening patients suspected of having an inherited disorder of methionine metabolism including: -Cystathionine beta-synthase deficiency (homocystinuria) -Methylenetetrahydrofolate reductase deficiency and its thermolabile...

MCLIP - Overview: Phospholipid (Cardiolipin) Antibodies, IgM, Serum

The following clinical situations, when used in conjunction with other criterial antiphospholipid antibody tests: -Unexplained arterial or venous thrombosis -A history of pregnancy morbidity defined as 1 or more unexplained deaths of a...

CYPZ - Overview: 21-Hydroxylase Gene, CYP21A2, Full Gene Analysis, Varies

Carrier screening and diagnosis of 21-hydroxylase deficient congenital adrenal hyperplasia (CAH) in individuals with a personal or family history of 21-hydroxylase deficiency, or as follow-up to positive CAH newborn screens and/or...

GNVWD - Overview: von Willebrand Disease, VWF and GP1BA Genes, Next-Generation Sequencing, Varies

Evaluating von Willebrand disease and platelet-type von Willebrand disease in patients with a personal or family history suggestive of von Willebrand disease Confirming von Willebrand disease or platelet-type von Willebrand disease...

SNS - Overview: Supplemental Newborn Screen, Blood Spot

Presymptomatic identification of disorders to allow for early initiation of treatment and consequent improvement in the long-term prognosis of affected patients The conditions identifiable by amino acid and acylcarnitine analysis are...

PUPYU - Overview: Purines and Pyrimidines Panel, Random, Urine

Evaluating patients with symptoms suspicious for disorders of purine and pyrimidine metabolism Monitoring patients with disorders of purine and pyrimidine metabolism Laboratory evaluation of primary and secondary hyperuricemias