ALBLI - Overview: Limited Bleeding Diathesis Profile Interpretation

Interpretation of testing performed as part of a profile to detect of the more common potential causes of abnormal bleeding (eg, factor deficiencies/hemophilia, von Willebrand disease, factor-specific inhibitors) and a simple screen to...

LY27B - Overview: HLA-B27, Blood

Assisting in the diagnostic process of ankylosing spondylitis, juvenile rheumatoid arthritis, and reactive arthritis

LEVE - Overview: Levetiracetam, Serum

Monitoring serum concentration of levetiracetam, particularly in patients with kidney disease Assessing compliance with levetiracetam therapy Assessing potential toxicity of levetiracetam

LID - Overview: Lidocaine, Serum

Assessing optimal lidocaine dosing during the acute management of ventricular arrhythmias following myocardial infarction or during cardiac manipulation such as surgery Assessing potential lidocaine toxicity

MPHNU - Overview: Methylphenidate and Metabolite, Random, Urine

Monitoring urine methylphenidate and ritalinic acid concentrations to assess compliance in patients

IGD - Overview: Immunoglobulin D (IgD), Serum

Providing information on the humoral immune status Identifying an IgD monoclonal gammopathy

GPI1 - Overview: Glucose Phosphate Isomerase Enzyme Activity, Blood

The evaluation of individuals with Coombs-negative chronic hemolysis

GD65C - Overview: Glutamic Acid Decarboxylase (GAD65) Antibody Assay, Spinal Fluid

Possible use in evaluating patients with autoimmune encephalitis, stiff-person syndrome, autoimmune ataxia, autoimmune epilepsy, and other acquired central nervous system disorders affecting gabaminergic neurotransmission

GPIC - Overview: Glucose Phosphate Isomerase Enzyme Activity, Blood

The evaluation of individuals with Coombs-negative chronic hemolysis

FIBAG - Overview: Fibrinogen Antigen, Plasma

Evaluation of fibrinogen deficiency Measuring fibrinogen in patients with elevated plasma levels of fibrin degradation products, patients receiving heparin, and in patients with antibodies to thrombin (following surgical use of topical...

FRUCT - Overview: Fructosamine, Serum

Monitoring intermediate (1-3 weeks) glycemic control Monitoring glycemic control in patients with shortened red blood cell survival

GABA - Overview: Gabapentin, Serum

Monitoring serum gabapentin concentrations Assessing compliance Adjusting dosage in patients

NOTRP - Overview: Nortriptyline, Serum

Monitoring nortriptyline concentration during therapy Evaluating potential nortriptyline toxicity May aid in evaluating patient compliance

NF4FS - Overview: Neurofascin-155 IgG4, Flow Cytometry, Serum

Evaluating patients with an underlying demyelinating neuropathy Diagnosis of a neurofascin-155 IgG4 mediated neuropathy

OMHC - Overview: Oxcarbazepine Metabolite, Serum

Monitoring serum concentration during oxcarbazepine therapy Assessing compliance Assessing potential toxicity

RCVBS - Overview: Recoverin-IgG Antibody, Immunoblot, Serum

Evaluating patients with suspected paraneoplastic retinopathy accompanying small cell carcinoma

PA - Overview: Procainamide and N-Acetylprocainamide, Serum

Monitoring therapy with procainamide Assessing compliance Evaluating procainamide toxicity

HSTNI - Overview: Troponin I, High Sensitivity, Plasma

Excluding the diagnosis of acute coronary syndromes Explaining troponin T elevations related to skeletal myopathy and/or assay interferences

THEO - Overview: Theophylline, Serum

Assessing and adjusting theophylline dosage for optimal therapeutic level Assessing theophylline toxicity

TPIC - Overview: Triosephosphate Isomerase Enzyme Activity, Blood

Evaluating individuals with chronic nonspherocytic hemolytic anemia Evaluating individuals with early onset neurologic impairment Genetic counseling for families with triosephosphate isomerase deficiency

TRMP - Overview: Trimipramine, Serum

Monitoring trimipramine concentration during therapy Evaluating potential trimipramine toxicity May aid in evaluating patient compliance

TOPI - Overview: Topiramate, Serum

Monitoring serum concentrations of topiramate Assessing compliance Assessing potential toxicity

VITE - Overview: Vitamin E, Serum

Monitoring of Vitamin E supplementation/treatment Potentially detecting Vitamin E overdoses

AHUGP - Overview: Atypical Hemolytic Uremic Syndrome (aHUS)/Thrombotic Microangiopathy (TMA) /Complement 3 Glomerulopathy (C3G) Gene Panel, Varies

Providing a genetic evaluation for patients with a personal or family history suggestive of atypical hemolytic uremic syndrome (aHUS), thrombotic microangiopathy (TMA), or complement 3 glomerulopathy (C3G) Establishing a diagnosis of...

ALPSG - Overview: Autoimmune Lymphoproliferative Syndrome (ALPS) Gene Panel, Varies

Providing a comprehensive genetic evaluation for patients with a personal or family history suggestive of autoimmune lymphoproliferative syndrome (ALPS) or related disorders Establishing a diagnosis of ALPS or a related disorder, allowing...

REVE2 - Overview: Erythrocytosis Evaluation, Blood

Definitive, comprehensive, and economic evaluation of an individual with JAK2-negative erythrocytosis associated with lifelong sustained increased hemoglobin or hematocrit

GNANG - Overview: Hereditary Angioedema Focused Gene Panel, Next-Generation Sequencing, Varies

Evaluating hereditary angioedema (HAE) with normal C1 inhibitor (C1INH) in patients with a suggestive personal or family history Confirming a diagnosis of HAE with normal C1INH with the identification of a known or suspected...

IMMAU - Overview: Inborn Errors of Immunity with Immune Dysregulation and Autoimmunity Gene Panel, Varies

Providing a comprehensive genetic evaluation for patients with a personal or family history suggestive of an inborn error of immunity (IEI) associated with immune dysregulation or autoimmunity Establishing a diagnosis of an IEI, allowing...

MEV1 - Overview: Methemoglobinemia Evaluation, Blood

Diagnosis of methemoglobinemia and sulfhemoglobinemia and possible hereditary (congenital) causes Differentiation of methemoglobinemia and sulfhemoglobinemia from other causes of cyanosis (eg, congenital heart disease)

PNEFS - Overview: Neuroimmunology Antibody Follow-up, Serum

Monitoring patients who have previously tested positive for one or more antibodies within the past 5 years in a Mayo Clinic Laboratories serum evaluation

SSH24 - Overview: Supersaturation Profile, Self-Collect, 24 Hour, Urine

Diagnosis and management of patients with renal lithiasis: -Predicting the likely composition of the stone, in patients who have a radiopaque stone, for whom stone analysis is not available -May aid in designing a treatment program Aiding...

SUP24 - Overview: Supersaturation Profile, 24 Hour, Urine

Diagnosis and management of patients with renal lithiasis: -Predicting the likely composition of the stone, in patients who have a radiopaque stone, for whom stone analysis is not available -May aid in designing a treatment program...

ASO - Overview: Antistrep-O Titer, Serum

Demonstration of acute or recent streptococcal infection

ADNAS - Overview: Anti-DNase B Titer, Serum

Demonstration of acute or recent streptococcal infection using anti-DNase B titer

AK1 - Overview: Adenylate Kinase Enzyme Activity, Blood

Evaluation of chronic nonspherocytic hemolytic anemia

AKC - Overview: Adenylate Kinase Enzyme Activity, Blood

Assessment of adenylate kinase activity as part of the evaluation of chronic nonspherocytic hemolytic anemia

APTTP - Overview: Activated Partial Thromboplastin Time, Plasma

Monitoring heparin therapy (unfractionated heparin) Screening for certain coagulation factor deficiencies Detection of coagulation inhibitors such as lupus anticoagulant, specific factor inhibitors, and nonspecific inhibitors

A2M - Overview: Alpha-2-Macroglobulin, Serum

Evaluating patients with nephrotic syndrome and pancreatitis

AACYL - Overview: Aminoacylase-1 Deficiency, Urine

Follow-up quantitation of abnormal organic acid elevations of N-acetylated amino acids, in particular N-acetylalanine, N-acetylglycine, N-acetylmethionine, and N-acetylglutamic acid Diagnosis of individuals with aminoacylase-1...

MMLYP - Overview: Antimicrobial Susceptibility Panel, Yeast, Varies

Determining in vitro quantitative antifungal susceptibility (minimum inhibitory concentration) of non-fastidious yeast As an aid in the management of certain circumstances, such as: -Refractory oropharyngeal infections due to Candida...

ABTIR - Overview: Antibody Titer, Blood and Serum

Monitoring antibody levels during pregnancy to help assess the risk of hemolytic disease of the newborn This test is not useful for monitoring the efficacy of Rh-immune globulin administration.

CD2B - Overview: CD2 Immunostain, Bone Marrow, Technical Component Only

Determining T-cell lineage

ANCA2 - Overview: Cytoplasmic Neutrophil Antibodies, Inflammatory Bowel Disease Panel, Serum

Measurement of antineutrophil cytoplastic antibodies as a part of a profile to aid in distinguishing between ulcerative colitis and Crohn disease in patients for whom the specific diagnosis is unclear based on endoscopic, pathologic, and...

C2FXN - Overview: C2 Complement, Functional, Serum

Investigation of a patient with a low (absent) hemolytic complement

ECHNG - Overview: Echinococcus Antibody, IgG, Serum

Detection of antibodies to Echinococcus granulosus

CLOM - Overview: Clomipramine, Serum

Determining whether a poor therapeutic response is attributable to noncompliance Monitoring serum concentration of clomipramine and norclomipramine to assist in optimizing the administered dose

COKEM - Overview: Cocaine and Metabolites Confirmation, Meconium

Detecting in utero drug exposure up to 5 months before birth

CRT24 - Overview: Creatinine, 24 Hour, Urine

Urinary creatinine, in conjunction with serum creatinine, is used to calculate the creatinine clearance, a measure of renal function Normalizing urinary analytes to account for the variation in urinary concentration

CD11C - Overview: CD11c Immunostain, Technical Component Only

Aiding in the diagnosis of hematological malignancies and identification of cells of the macrophage/dendritic cell lineage within tissues

ECADB - Overview: E-Cadherin Immunostain, Bone Marrow, Technical Component Only

Differentiation between lobular and ductal neoplasms of the breast