ATPCO - Overview: Anal ThinPrep Cytology with Human Papillomavirus (HPV) Co-Test, Varies
Detection of malignant and premalignant changes Detection of high-risk (HR) genotypes associated with the development of anal cancer Individual genotyping of human papillomavirus (HPV)-16 and HPV-18, if present May aid in triaging men...
BAP1Z - Overview: BAP1-Tumor Predisposition Syndrome, BAP1 Full Gene Analysis, Varies
Evaluating patients with a personal or family history suggestive of BAP1-tumor predisposition syndrome (BAP1-TPDS) Establishing a diagnosis of BAP1-TPDS allowing for targeted cancer surveillance based on associated risks Identifying...
SESPF - Overview: Sesame Seed, IgE, with Reflex to Sesame Seed Component, IgE, Serum
Evaluating patients with suspected sesame seed allergy
PNTOR - Overview: Streptococcus pneumoniae IgG Antibodies, Total, with Reflex, Serum
Assessing the IgG antibody response to active immunization with nonconjugated 23-valent pneumococcal vaccines Assessing the IgG antibody response to active immunization with conjugated 13-valent, 15-valent and 20-valent pneumococcal...
TICKS - Overview: Tick-Borne Disease Antibodies Panel, Serum
Evaluation of the most common tick-borne diseases found in the United States, including Lyme disease, human monocytic and granulocytic ehrlichiosis, and babesiosis Evaluation of patients with a history of, or suspected, tick exposure who...
DHES1 - Overview: Dehydroepiandrosterone Sulfate, Serum
Diagnosis and differential diagnosis of hyperandrogenism (in conjunction with measurements of other sex steroids) An adjunct in the diagnosis of congenital adrenal hyperplasia Diagnosis and differential diagnosis of premature adrenarche
CMAP - Overview: Chromosomal Microarray, Prenatal, Amniotic Fluid/Chorionic Villus Sampling
Prenatal diagnosis of copy number changes (gains or losses) across the entire genome Determining the size, precise breakpoints, gene content, and any unappreciated complexity of abnormalities detected by other methods, such as conventional...
CAH21 - Overview: Congenital Adrenal Hyperplasia (CAH) Profile for 21-Hydroxylase Deficiency, Serum
Preferred screening test for congenital adrenal hyperplasia (CAH) caused by 21-hydroxylase deficiency Part of a battery of tests to evaluate women with hirsutism or infertility, which can result from adult-onset CAH
G6PDC - Overview: Glucose 6 Phosphate Dehydrogenase Enzyme Activity, Blood
Evaluation of individuals with episodic or chronic Coombs-negative nonspherocytic hemolytic anemia Rapid testing to assess glucose-6-phosphate dehydrogenase (G6PD) enzyme capacity prior to rasburicase or other therapies that may cause...
PFAPE - Overview: Fatty Acid Profile, Essential, Plasma
Evaluating the nutritional intake and intestinal absorption of essential fatty acids using plasma specimens Identifying deficiency of essential and other nutritionally beneficial fatty acids Monitoring treatment of patients with essential...
NGPCM - Overview: MayoComplete Plasma Cell Myeloma, Next-Generation Sequencing, Varies
Evaluating multiple myeloma at the time of diagnosis and at disease relapse or when changing clinical management to provide prognostic information and determine potential therapeutic implications
FSUAB - Overview: Sulfatide Autoantibody Test
Sulfatide Autoantibody Test
FIERA - Overview: IgE Receptor Antibody
The test detects functional autoantibodies to the Fc-epsilon receptor (high affinity IgE receptor) or to IgE and is useful in the evaluation of chronic urticaria.
FABP2 - Overview: Allergic Bronchopulmonary Aspergillosis Panel II
Allergic Bronchopulmonary Aspergillosis Panel II
SHUR - Overview: Schistosoma Exam, Random, Urine
Aiding in the diagnosis of schistosomiasis infections involving the urinary tract
UHSD2 - Overview: Hemosiderin, Random, Urine
Detecting hemosiderinuria, secondary to excess hemolysis, as in incompatible blood transfusions, severe acute hemolytic anemia, or hemochromatosis for external patients.
Detecting lead exposure using nail specimens
Identification of breast and urinary cancer, among others
ATR - Overview: Isoagglutinin Titer, Anti-A, Serum
Evaluation of individuals with possible hypogammaglobulinemia Investigation of suspected roundworm infections
BTR - Overview: Isoagglutinin Titer, Anti-B, Serum
Evaluation of individuals with possible hypogammaglobulinemia
MSCG - Overview: Collagenofibrotic Glomerulopathy Confirmation, Mass Spectrometry
Aiding in the diagnosis of collagenofibrotic glomerulopathy
RUFI - Overview: Rufinamide, Serum
Monitoring serum rufinamide concentrations, assessing compliance, and adjusting dosage in patients receiving other drugs that interact pharmacokinetically with rufinamide (ie, drugs that induce liver CYP3A4 enzymes) and may be helpful in...
BRBPS - Overview: Broad Range Bacterial PCR and Sequencing, Varies
Detecting and identifying bacteria (including mycobacteria) from normally sterile sources, including synovial fluid; body fluids such as pleural, peritoneal, and pericardial fluids, cerebrospinal fluid; and both fresh and formalin-fixed...
CDG - Overview: Carbohydrate Deficient Transferrin for Congenital Disorders of Glycosylation, Serum
Screening for congenital disorders of glycosylation This test is not useful for screening patients for chronic alcohol abuse.
HVDIP - Overview: HIV-1 and HIV-2 Antibody Confirmation and Differentiation, Plasma
Confirmation and differentiation of HIV-1 and HIV-2 antibodies in plasma specimens that show reactive results with third-(HIV-1/-2 antibody only) and 4th-generation (HIV antigen and antibody) HIV serologic assays This test is not useful as...
NMEM - Overview: Red Blood Cell Membrane Disorders Gene Panel, Next-Generation Sequencing, Varies
Providing a comprehensive genetic evaluation for patients with a personal or family history suggestive of a red blood cell (RBC) membrane disorder Second-tier testing for patients in whom previous targeted gene variant analyses were...
Evaluating patients with suspected stiff-person syndrome (classical or focal forms, such as stiff-limb or stiff-trunk) and progressive encephalomyelitis with rigidity and myoclonus using serum specimens
NUTHX - Overview: Hazelnut-Food Components, IgE, Serum
Evaluation of patients with suspected hazelnut-food allergy to one of 4 hazelnut-food components
HVPPS - Overview: HIV-1 and HIV-2 Antibody Confirmation and Differentiation Prenatal, Serum
Confirmation and differentiation of HIV-1 and HIV-2 antibodies in serum specimens from prenatal patients who show reactive results with 3rd- (HIV-1/-2 antibody only) and 4th-generation (HIV antigen and antibody) HIV serologic assays This...
CRCGP - Overview: Hereditary Gastrointestinal Cancer Panel, Varies
Evaluating patients with a personal or family history suggestive of a hereditary gastrointestinal cancer or hereditary polyposis syndrome Establishing a diagnosis of a hereditary gastrointestinal cancer syndrome or hereditary polyposis...
PANCP - Overview: Hereditary Pancreatic Cancer Panel, Varies
Evaluating patients with a personal or family history suggestive of a hereditary pancreatic cancer syndrome Establishing a diagnosis of a hereditary pancreatic cancer syndrome, allowing for targeted cancer surveillance based on associated...
HVDSP - Overview: HIV-1 and HIV-2 Antibody Confirmation and Differentiation, Prenatal, Plasma
Confirmation and differentiation of HIV-1 and HIV-2 antibodies in plasma specimens from prenatal patients who show reactive results with 3rd- (HIV-1/-2 antibody only) and 4th-generation (HIV antigen and antibody) HIV serologic assays This...
THYRP - Overview: Hereditary Thyroid Cancer Panel, Varies
Evaluating patients with a personal or family history suggestive of a hereditary thyroid cancer syndrome Establishing a diagnosis of a hereditary thyroid cancer syndrome, allowing for targeted surveillance based on associated...
HIVDI - Overview: HIV-1 and HIV-2 Antibody Confirmation and Differentiation, Serum
Confirmation and differentiation of HIV-1 and HIV-2 antibodies in serum specimens that show reactive results with third-(HIV-1/-2 antibody only) and 4th-generation (HIV antigen and antibody) HIV serologic assays Confirmation and...
Identifying HIV-1 genotypic mutations associated with resistance to nucleotide and non-nucleoside reverse-transcriptase inhibitors, protease inhibitors, and integrase strain transfer inhibitors Guiding initiation or change of combination...
MCSRC - Overview: MayoComplete Comprehensive Sarcoma Panel, Next-Generation Sequencing, Tumor
Primarily for identifying mutations that help in the diagnosis of specific soft tissue and bone tumors (sarcoma) Secondarily for identifying mutations that have therapeutic or prognostic significance Assessing microsatellite instability...
ANST - Overview: Androstenedione, Serum
Diagnosis and differential diagnosis of hyperandrogenism, in conjunction with measurements of other sex steroids Diagnosis of congenital adrenal hyperplasia (CAH), in conjunction with measurement of other androgenic precursors,...
SRYF - Overview: Sex-Determining Region Y, Yp11.3 Deletion, FISH
Detecting the deletion or addition of the SRY gene in conjunction with conventional chromosome studies
DHRP - Overview: Dihydrorhodamine Flow Cytometric Phorbol Myristate Acetate Test, Blood
Evaluating chronic granulomatous disease (CGD), X-linked and autosomal recessive forms, complete myeloperoxidase deficiency Monitoring chimerism and nicotinamide adenine dinucleotide phosphate oxidase (NOX) function post-hematopoietic cell...
UOSMU - Overview: Osmolality, Random, Urine
Assessing the concentrating and diluting ability of the kidney
ACMA - Overview: Acetaminophen, Serum
Monitoring toxicity in overdose cases
UREDF - Overview: Reducing Substance, Feces
Assisting in the differentiation between osmotic and nonosmotic diarrhea Screening test for: -Diarrhea from disaccharidase deficiencies, (eg, lactase deficiency) -Monosaccharide malabsorption
DLAU - Overview: D-Lactate, Urine
Preferred test for diagnosing D-lactate acidosis, especially in patients with jejunoileal bypass and short-bowel syndrome
HPVE6 - Overview: Human Papillomavirus (HPV) High-Risk E6/E7, RNA In Situ Hybridization
Stratification of oropharyngeal squamous cell carcinoma
HK1 - Overview: Hexokinase Enzyme Activity, Blood
The evaluation of individuals with Coombs-negative chronic hemolysis
23FBG - Overview: Fibroblast Growth Factor-23 (FGF23), In Situ Hybridization
Assessing fibroblast growth factor-23 (FGF23) expression
MURA - Overview: Lysozyme (Muramidase), Plasma
As a screening test for ocular sarcoidosis Confirming marked increases in the granulocyte or monocyte pools as in granulocytic or monocytic leukemias, myeloproliferative disorders, and malignant histiocytosis Following the course of...
MONOS - Overview: Infectious Mononucleosis, Rapid Test, Serum
Diagnosis of Epstein-Barr virus mononucleosis
CEASF - Overview: Carcinoembryonic Antigen (CEA), Spinal Fluid
Detecting meningeal carcinomatosis and intradural or extradural infiltration Differentiating brain parenchymal metastasis from adenocarcinoma or squamous-cell carcinoma
RAT10 - Overview: Citrate/Creatinine Ratio, Urine
Calculating the citrate concentration per creatinine Diagnosing risk factors for patients with calcium kidney stones Monitoring results of therapy in patients with calcium stones or renal tubular acidosis
Information: Interpreting Laboratory Tests to Determine New vs. Residual Use of Marijuana - Insights
In this month's "Hot Topic," Paul Jannetto, Ph.D., identifies how to determine new vs. residual use of marijuana in a patient, and teaches how to calculate the carboxy-tetrahydrocannabinol (carboxy-THC)...
Laboratory and Pathology Research Roundup: March 12 - Insights
known. We performed laser microdissection (LCM) of glomeruli followed by mass spectrometry (MS) in 12 cases each of DDD, C3GN, and pretransplant kidney control biopsies....
COVID-19: At-home sample collection vs. at-home testing - Insights
The concept of at-home testing for COVID-19 sounds straightforward. But there's nuance to it that's important to understand. Right now, an at-home test for COVID-19 is not available, although there may be one coming soon. But in some areas,...
Clinic Laboratory and Pathology Research Roundup: Nov. 12 - Insights
This week’s Research Roundup highlights a mechanism for preventing asymmetric histone segregation onto replicating DNA strands.
Transfusion Toons: A1 vs. A2 - Insights
Justin Kreuter, M.D., Clinical Pathologist and Medical Director of the Mayo Clinic Blood Donor Center in Rochester, Minnesota, and Theresa Malin, an Education Specialist in Transfusion Medicine at Mayo Clinic, have launched “Transfusion...