Test Catalog

Test Id : UREDF

Reducing Substance, Feces

Useful For
Suggests clinical disorders or settings where the test may be helpful

Assisting in the differentiation between osmotic and non-osmotic diarrhea

 

Screening test for:

-Diarrhea from disaccharidase deficiencies, (eg, lactase deficiency)

-Monosaccharide malabsorption

Method Name
A short description of the method used to perform the test

Benedict's Copper Reduction Reaction

NY State Available
Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Reporting Name
Lists a shorter or abbreviated version of the Published Name for a test

Reducing Substance, F

Aliases
Lists additional common names for a test, as an aid in searching

Stool sugar

Fecal sugar

UREDF

Specimen Type
Describes the specimen type validated for testing

Fecal

Specimen Required
Defines the optimal specimen required to perform the test and the preferred volume to complete testing

Supplies: Stool container, Small (Random), 4 oz Random (T288)

Container/Tube: Fecal container

Specimen Volume: 3 g

Collection Instructions:

1. Collect a loose, unpreserved, random fecal specimen.

2. Freeze immediately.

Additional Information: If additional tests are ordered, aliquot and separate sample prior to freezing to allow 1 container per test.

Forms

If not ordering electronically, complete, print, and send a Gastroenterology and Hepatology Client Test Request (T728) with the specimen.

Specimen Minimum Volume
Defines the amount of sample necessary to provide a clinically relevant result as determined by the Testing Laboratory

2 g

Reject Due To
Identifies specimen types and conditions that may cause the specimen to be rejected

Urine and stool mixed Reject

Specimen Stability Information
Provides a description of the temperatures required to transport a specimen to the performing laboratory, alternate acceptable temperatures are also included

Specimen Type Temperature Time Special Container
Fecal Frozen (preferred) 7 days

Useful For
Suggests clinical disorders or settings where the test may be helpful

Assisting in the differentiation between osmotic and non-osmotic diarrhea

 

Screening test for:

-Diarrhea from disaccharidase deficiencies, (eg, lactase deficiency)

-Monosaccharide malabsorption

Clinical Information
Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

Fecal reducing substances (carbohydrates) aids in determining the underlying cause of diarrhea. Elevations in fecal reducing substances help distinguish between osmotic diarrhea caused by abnormal excretion of various sugars as opposed to diarrhea caused by viruses and parasites. Increased reducing substances in stool are consistent with, but not diagnostic of, primary or secondary disaccharidase deficiency (primarily lactase deficiency) or intestinal monosaccharide malabsorption. Similar intestinal absorption deficiencies are associated with short bowel syndrome and necrotizing enterocolitis.

Reference Values
Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

Negative or trace

Interpretation
Provides information to assist in interpretation of the test results

Negative: negative

Normal: < or =0.25 g/dL (trace)

Suspicious: >0.25 to 0.50 g/dL (grade 1)

Abnormal: >0.50 g/dL (grade 2-4)

Cautions
Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances

This test has poor sensitivity for oligosaccharides.

 

Antibiotics can alter the intestinal flora and affect acid production.

 

False-positive reactions due to drugs (salicylates, penicillin, ascorbic acid, nalidixic acid, cephalosporins, and probenecid) are possible.

 

Feces may be contaminated with urine, in which case glycosuria will give false-positive results.

 

Diaper collections can be falsely decreased as the fluid portion containing water soluble sugars is absorbed into the diaper.

 

Ambient transport temperatures result in growth of bacteria that consume sugars resulting in falsely decreased values.

Clinical Reference
Recommendations for in-depth reading of a clinical nature

1. Siddiqui HA, Salwen MJ, Shaikh MF, Bowne WB: Laboratory diagnosis of gastrointestinal and pancreatic disorders. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 23rd ed. Elsevier; 2017:306-323

2. Branski D: Disorders of malabsorption. In: Kleigman RM, Stanton BF, St..Geme JW, eds. Nelson Textbook of Pediatrics. Elsevier; 2016:1831-1850

3. Bhatia J, Prihoda AR, Richardson CJ: Parenteral antibiotics and carbohydrate intolerance in term neonates. Am J Dis Child. 1986;140(2):111-113

4. Book LS, Herbst JJ, Jung AL: Carbohydrate malabsorption in necrotizing enterocolitis. Pediatrics. 1976;57:201-204

5. Krom FA, Frank CG: Clinitesting neonatal stools. Neonatal Network. 1989;8(2):37-40

6. Qualitative methods for total reducing substances. In: Tietz Textbook of Clinical Chemistry. 2nd ed. 1994;968-969

Method Description
Describes how the test is performed and provides a method-specific reference

Copper sulfate in the tablet reacts with reducing substances converting cupric sulfate to cuprous oxide.(Package insert: AimTab Reducing Substances Tablets. Germaine Laboratories, Inc; 12/2015)

PDF Report
Indicates whether the report includes an additional document with charts, images or other enriched information

No

Day(s) Performed
Outlines the days the test is performed. This field reflects the day that the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time before the test is performed. Some tests are listed as continuously performed, which means that assays are performed multiple times during the day.

Monday through Saturday

Report Available
The interval of time (receipt of sample at Mayo Clinic Laboratories to results available) taking into account standard setup days and weekends. The first day is the time that it typically takes for a result to be available. The last day is the time it might take, accounting for any necessary repeated testing.

1 to 3 days

Specimen Retention Time
Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded

7 days

Performing Laboratory Location
Indicates the location of the laboratory that performs the test

Rochester

Fees
Several factors determine the fee charged to perform a test. Contact your U.S. or International Regional Manager for information about establishing a fee schedule or to learn more about resources to optimize test selection.

  • Authorized users can sign in to Test Prices for detailed fee information.
  • Clients without access to Test Prices can contact Customer Service 24 hours a day, seven days a week.
  • Prospective clients should contact their Regional Manager. For assistance, contact Customer Service.

Test Classification
Provides information regarding the medical device classification for laboratory test kits and reagents. Tests may be classified as cleared or approved by the US Food and Drug Administration (FDA) and used per manufacturer instructions, or as products that do not undergo full FDA review and approval, and are then labeled as an Analyte Specific Reagent (ASR) product.

This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information
Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Clinic Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.

CPT codes are provided by the performing laboratory.

84376

Test Setup Resources

Setup Files
Test setup information contains test file definition details to support order and result interfacing between Mayo Clinic Laboratories and your Laboratory Information System.

Excel | Pdf

Sample Reports
Normal and Abnormal sample reports are provided as references for report appearance.

Normal Reports | Abnormal Reports

SI Sample Reports
International System (SI) of Unit reports are provided for a limited number of tests. These reports are intended for international account use and are only available through MayoLINK accounts that have been defined to receive them.

SI Normal Reports | SI Abnormal Reports