VITAE - Overview: Vitamin A and Vitamin E, Serum

Diagnosing vitamin A deficiency and toxicity Evaluating persons with intestinal malabsorption of lipids Monitoring of Vitamin E supplementation/treatment

SRAU - Overview: Serotonin Release Assay, Unfractionated Heparin, Mass Spectrometry, Serum

Detecting heparin-dependent platelet activating antibodies implicated in the pathogenesis of heparin-induced thrombocytopenia

USTEK - Overview: Ustekinumab Quantitation with Antibodies, Serum

Evaluation of loss of response to therapy Quantification of ustekinumab in human serum Trough level quantitation for evaluation of patients treated with ustekinumab Detection of antibodies to ustekinumab in human serum

FACT - Overview: Filamentous-Actin (F-actin) Antibody, IgG, Serum

Evaluation of patients with hepatitis of unknown origin associated with hypergammaglobulinemia and/or abnormal liver enzymes This test may also be useful for confirming positivity for smooth muscle antibodies.

HVA - Overview: Homovanillic Acid, 24 Hour, Urine

Screening children for catecholamine-secreting tumors using a 24-hour urine collection when requesting homovanillic acid only Monitoring neuroblastoma treatment Screening patients with possible inborn errors of catecholamine metabolism

AGNTC - Overview: Anti-Glial/Neuronal Nuclear Antibody-Type 1 (AGNA-1) Titer, Spinal Fluid

Reporting an end titer result from cerebrospinal fluid (CSF) specimens Serological evaluation using CSF specimens from patients who present with a subacute neurological disorder of undetermined etiology, especially those with risk factors...

BETV2 - Overview: BET v2 (Profilin), IgE, Serum

Evaluation of patients suspected birch pollen allergy Evaluation of patients with suspected peanut allergy Evaluation of patients with oral allergy syndrome to other pollens or plant-based foods Testing for IgE antibodies is not useful...

CTX - Overview: Beta-CrossLaps, Serum

Monitoring antiresorptive therapies (eg, bisphosphonates and hormone replacement therapy) in postmenopausal women treated for osteoporosis and individuals diagnosed with osteopenia An adjunct in the diagnosis of medical conditions...

CLLMD - Overview: Chronic Lymphocytic Leukemia (CLL) Monitoring Minimal Residual Disease Detection, Flow Cytometry, Varies

Confirming the presence or absence of minimal residual disease in patients with known chronic lymphocytic leukemia who are either post-chemo/immunotherapy or post-bone marrow transplant

LCMSP - Overview: Microsporidia species, Molecular Detection, PCR, Varies

Detecting Enterocytozoon bieneusi and Encephalitozoon species in fecal and urine specimens to support the clinical diagnosis of microsporidiosis

IN16Q - Overview: CBFB::MYH11 Inversion(16), Quantitative Detection and Minimal Disease Risk Monitoring, qRT-PCR, Varies

Detection of CBFB::MYH11 gene fusion in patients recently diagnosed with acute myeloid leukemia (AML) Minimal residual disease monitoring during the clinical and therapeutic course of patients with AML

CRAV - Overview: Cortisol, Right Adrenal Vein, Serum

Testing cortisol levels in the right adrenal vein Second-order testing when cortisol measurement by immunoassay gives results that are not consistent with clinical symptoms, or if patients are known to, or suspected of, taking exogenous...

DNSAG - Overview: Dengue Virus NS1 Antigen, Serum

Aiding in the diagnosis of dengue virus infection

PREGN - Overview: Pregnenolone, Serum

An ancillary test for congenital adrenal hyperplasia, particularly in situations in which a diagnosis of both 21- and 11-hydroxylase deficiency have been ruled out Confirming a diagnosis of 3-beta-hydroxy dehydrogenase deficiency

CLAV - Overview: Cortisol, Left Adrenal Vein, Serum

Testing cortisol levels in the left adrenal vein Second-order testing wen cortisol measurement by immunoassay gives results that are not consistent with clinical symptoms, or if patients are known to, or suspected of, taking exogenous...

CDPCR - Overview: Clostridioides difficile Toxin, PCR, Feces

Sensitive, specific, and rapid diagnosis of Clostridioides (Clostridium) difficile-associated diarrhea and pseudomembranous colitis The test is not recommended as a test of cure.

HGBCE - Overview: Hemoglobin Variant, A2 and F Quantitation, Blood

Monitoring patients with sickling disorders who have received hydroxyurea or transfusion therapy This test is not intended for diagnostic purposes. This test is not useful for screening purposes.

STHPV - Overview: ThinPrep Screen with Human Papillomavirus (HPV) Reflex, Varies

Managing and triaging of patients, aged 21 years or older, with abnormal Pap results Screening for detection of high-risk (HR) human papillomavirus (HPV) genotypes associated with the development of cervical cancer Aids in triaging...

PCDGG - Overview: Primary Ciliary Dyskinesia Gene Panel, Varies

Providing a genetic evaluation for patients with a personal or family history suggestive of primary ciliary dyskinesia Establishing a diagnosis of primary ciliary dyskinesia

SP142 - Overview: Programmed Death-Ligand 1 (PD-L1) (SP142), Semi-Quantitative Immunohistochemistry, Manual

Identification of neoplasms expressing programmed cell death 1-ligand 1 (clone SP142)

22C3 - Overview: Programmed Death-Ligand 1 (PD-L1) (22C3), Semi-Quantitative Immunohistochemistry, Manual

Identification of neoplasms expressing programmed cell death 1-ligand 1 (clone 22C3)

VITB3 - Overview: Vitamin B3 and Metabolites, Plasma

Assisting in the diagnosis of suspected vitamin B3 deficiency or toxicity May be useful in determining response to therapy

HERGN - Overview: HER2, Gastric/Esophageal, Semi-Quantitative Immunohistochemistry, Manual, No Reflex

Determining overexpression of HER2 protein of gastric and esophageal adenocarcinoma in formalin-fixed, paraffin-embedded tissue sections (no reflex to FISH testing)

FMNPP - Overview: Motor Neuropathy Panel

Motor Neuropathy Panel

B2M - Overview: Beta-2-Microglobulin, Serum

Prognosis assessment of multiple myeloma Evaluation of renal tubular disorders

FMSS2 - Overview: Maternal Serum Screening, Integrated, Specimen #2, Alpha Fetoprotein, Hcg, Estriol, and Inhibin A

Helpful to identify pregnancies at increased risk of having a child with Down syndrome (trisomy 21), Open Neural Tube Defect (ONTD, spina bifida) and trisomy 18 (T18). This test is not diagnostic. The patient information provided with the...

SGSS - Overview: Synthetic Glucocorticoid Screen, Serum

Confirming the presence of listed synthetic glucocorticoids (see Interpretation) Confirming the cause of secondary adrenal insufficiency This test is not useful for detection of fluticasone propionate.

SEAFP - Overview: Seafood Allergen Profile, Serum

Establishing a diagnosis of an allergy to seafood Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or anaphylactic episode -To confirm sensitization prior to...

C5B9 - Overview: SC5b-9 Level Terminal Complement Complex, Plasma

Detecting increased complement activation

SABP - Overview: Streptococcal Antibodies Profile, Serum

Demonstration of acute or recent streptococcal infection using both antistreptolysin O and anti-DNase B titers

SCERG - Overview: Saccharomyces cerevisiae Antibody, IgG, Serum

Measuring IgG anti-Saccharomyces cerevisiae antibodies as a part of a profile to aid in distinguishing between ulcerative colitis and Crohn disease in patients for whom the specific diagnosis is unclear based on endoscopic, pathologic, and...

CALU - Overview: Calcium, 24 Hour, Urine

Evaluation of calcium oxalate and calcium phosphate kidney stone risk, and calculation of urinary supersaturation Evaluation of bone diseases, including osteoporosis and osteomalacia

CHOU - Overview: Carbohydrate, Urine

Screening for conditions associated with increased excretion of carbohydrates, including inborn errors of fructose and galactose metabolism. This test is not recommended as a follow up test for abnormal newborn screening for galactosemia.

SGSU - Overview: Synthetic Glucocorticoid Screen, Random, Urine

Confirming the presence of the listed synthetic glucocorticoids Confirming the cause of secondary adrenal insufficiency

C6FX - Overview: C6 Complement, Functional, Serum

Diagnosis of C6 deficiency Investigation of a patient with an undetectable total complement level

PAS3 - Overview: Pediatric Allergy Screen <3 Years, Serum

Establishing a diagnosis of an allergy to egg whites, milk, wheat, soybeans, and house dust mites Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or...

GALZ - Overview: Galactosemia, GALT Gene, Full Gene Analysis, Varies

Identifying variants in individuals who test negative for the common variants and who have a biochemical diagnosis of galactosemia or galactose-1-phosphate uridyltransferase activity levels indicative of carrier status

PMCAG - Overview: Postmortem Cardiomyopathy and Arrhythmia Gene Panel, Tissue

Providing a comprehensive postmortem genetic evaluation in the setting of a sudden death attributed to cardiomyopathy or suspicious for cardiac arrhythmia or with a personal or family history suggestive of a hereditary form of...

PBCPN - Overview: Primary Biliary Cholangitis Antibody Panel, Serum

Evaluation of at-risk or previously diagnosed primary biliary cholangitis patients with new features of other liver diseases or systemic autoimmune diseases

U1A1Q - Overview: Uridine Diphosphate (UDP) Glucuronosyltransferase 1A1 TA Repeat Genotype, UGT1A1, Varies

Identifying individuals who are at increased risk of adverse drug reactions with drugs that are metabolized by uridine diphosphate glucuronosyltransferase (UGT1A1); especially irinotecan but also atazanavir, nilotinib, pazopanib, and...

HCCGS - Overview: Hepatocellular Carcinoma Risk Panel with GALAD Score, Serum

Risk assessment for development of hepatocellular carcinoma in patients with chronic liver disease

RETZZ - Overview: Multiple Endocrine Neoplasia Type 2 Syndrome, RET, Full Gene Analysis, Varies

Evaluating patients with a personal or family history suggestive of a multiple endocrine neoplasia type 2 (MEN2) or Hirschsprung disease (HSCR) Establishing a diagnosis of MEN2 or HSCR allowing for targeted cancer surveillance based on...

CDIFS - Overview: Clostridioides difficile Culture with Antimicrobial Susceptibilities, Varies

Providing an isolate suitable for antimicrobial susceptibility testing to direct antimicrobial therapy of extraluminal infections and in cases of treatment failure

QUIN - Overview: Quinidine, Serum

Assessing and adjusting quinidine dosage for optimal therapeutic level Assessing quinidine toxicity

HPVE6 - Overview: Human Papillomavirus (HPV) High-Risk E6/E7, RNA In Situ Hybridization

Stratification of oropharyngeal squamous cell carcinoma

JCV - Overview: JC Virus Detection by In Situ Hybridization

Confirming a clinical and histopathologic diagnosis of progressive multifocal leukoencephalopathy

MDNS - Overview: Methadone and Metabolites, Serum

Compliance monitoring of methadone Assessment of methadone toxicity

HPVLR - Overview: Human Papillomavirus (HPV) Low Risk, In Situ Hybridization

Detection of human papillomavirus from low-risk genotypes (6, 11)

F8INP - Overview: Hemophilia A F8 Gene, Intron 1 and 22 Inversion Mutation Analysis, Prenatal

Prenatal testing for hemophilia A when a variant has not been identified in the family

SMN1Z - Overview: SMN1 Gene, Full Gene Analysis, Varies

Confirming a diagnosis of spinal muscular atrophy due to nucleotide variants in SMN1 gene Second-tier carrier screening when there is a family history of spinal muscular atrophy, but an affected individual is not available for testing, or...