Detection and identification of prescription or over the counter drugs frequently found in drug overdose or used with a suicidal intent
Qualitatively identifying drugs present in the specimen; quantification of identified drugs, when available, may be performed upon client request
This test is not intended for therapeutic drug monitoring or compliance testing.
This test is not intended for use in employment-related testing.
This test is not useful for drugs of abuse or illicit drug testing, including benzodiazepines, opioids, barbiturates, cocaine, amphetamine type stimulants.
Gas Chromatography-Mass Spectrometry (GC-MS)
acetaminophen
amitriptyline
amobarbital
bupropion
butabarbital
butalbital
caffeine
carbamazepine
carisoprodol
chlorpheniramine
chlorpromazine
citalopram
clomipramine
clozapine
codeine
cyclobenzaprine
dextromethorphan
diazepam
diphenhydramine
doxepin
doxylamine
fentanyl
fluoxetine
guaifenesin
ibuprofen
imipramine
lamotrigine
levetiracetum
lidocaine
meperidine
mephobarbital
meprobamate
metaxalone
methadone
methsuximide
methylphenidate
midazolam
mirtazepine
naproxen
nordiazepam
nortriptyline
oxcarbazepine metabolite
pentobarbital
phenobarbital
primidone
promethazine
propofol
salicylate
secobarbital
sertraline
strychnine
theophylline
thioridazine
topiramate
tramadol
trazodone
trimipramine
venlafaxine
zaleplon
zolpidem
Serum Red
For chain-of-custody testing, order DSSX / Drug Screen, Prescription/Over the Counter, Chain of Custody, Serum.
Question ID | Description | Answers |
---|---|---|
SU_DR | Suspect Drug |
Collection Container/Tube: Red top (serum gel/SST tubes are not acceptable)
Submission Container/Tube: Plastic vial
Specimen Volume: 2.75 mL
Collection Instructions: Centrifuge and aliquot serum into plastic vial within 2 hours of collection.
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.
1.1 mL
Gross hemolysis | OK |
Gross lipemia | OK |
Gross icterus | OK |
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Serum Red | Refrigerated (preferred) | 14 days | |
Frozen | 14 days | ||
Ambient | 3 hours |
Detection and identification of prescription or over the counter drugs frequently found in drug overdose or used with a suicidal intent
Qualitatively identifying drugs present in the specimen; quantification of identified drugs, when available, may be performed upon client request
This test is not intended for therapeutic drug monitoring or compliance testing.
This test is not intended for use in employment-related testing.
This test is not useful for drugs of abuse or illicit drug testing, including benzodiazepines, opioids, barbiturates, cocaine, amphetamine type stimulants.
This test looks for a broad spectrum of prescription and over-the-counter (OTC) drugs. It is designed to detect drugs that have toxic effects, as well as known antidotes or active therapies that a clinician can initiate to treat the toxic effect. The test is intended to help physicians manage an apparent overdose or intoxicated patient, or to determine if a specific set of symptoms might be due to the presence of drugs. This test is not appropriate for drugs of abuse or illicit drug testing, including benzodiazepines, opioids, barbiturates, cocaine, and amphetamine type stimulants.
Drugs of toxic significance that are not detected by this test are: digoxin, lithium, and many drugs of abuse or illicit drugs, some benzodiazepines, and some opioids.
For more information see Emergency/Overdose for detection limits for drugs detected in this test.
Drugs detected are presumptive. Additional testing may be required to confirm the presence of any drugs detected.
The drugs that are detected by this test are listed in Emergency/Overdose.
The pharmacology of each drug determines how the test should be interpreted. A detailed discussion of each drug is beyond the scope of this text. If you wish to have a report interpreted, call 800-533-1710 and ask for a toxicology consultant.
Each report will indicate the drugs detected.
Specimens collected in serum gel tubes are not acceptable, as the drug/analyte can absorb on the gel and lead to falsely decreased concentrations.
1. Langman LJ, Bechtel LK, Meier BM, Holstege C: Clinical toxicology. In: Rifai N, Horvath AR, Wittwer CT, eds. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. 6th ed. Elsevier; 2018:1294
2. Baselty RC: Disposition of Toxic Drugs and Chemicals in Man. 10th ed. Biomedical Publications; 2014
Screening is by gas chromatography-mass spectroscopy.(Unpublished Mayo method)
Monday through Sunday
This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.
80307
Test Id | Test Order Name | Order LOINC Value |
---|---|---|
DSS | Drug Screen, Prescription/OTC, S | 20785-2 |
Result Id | Test Result Name |
Result LOINC Value
Applies only to results expressed in units of measure originally reported by the performing laboratory. These values do not apply to results that are converted to other units of measure.
|
---|---|---|
31168 | Chain of Custody | 77202-0 |
31072 | Drugs detected: | 20785-2 |