Container/Tube: Red Top
Preferred: Red top tube
Acceptable: Serum gel tube
Specimen Volume: 2 mL
Collection Instructions: Draw blood in a plain, red-top tube(s). Separate serum from cells immediately by centrifugation and aliquot into a polypropylene or similar plastic tube. Send 2 mL of serum frozen in plastic vial.
1. The following information is required:
A. Specimen Type (source)
B. Dose (specify PO, IV, IM)
C. Date and time of last dose (for IV start/end time)
2. If the time of last dose and the blood draw are not accurately recorded, accurate interpretation of the concentration is not possible.
|Hemolysis||Mild OK; Gross reject|
|Other||Samples thawed greater than 6 hours.|
|Specimen Type||Temperature||Time||Special Container|
|Serum||Frozen (preferred)||365 days|
The target range for mycobacterial infections is 8 to 24 mcg/mL 2 hours after oral dose or 2 hours after the end of intravenous infusion. Samples drawn later than 2 hours after the dose will often display concentrations below the stated range.
Rifampin generally should be given as a single daily dose. If the patient is receiving 2 small daily doses, consider combining the doses and rechecking the concentration.
Rifampin absorption may be reduced by food. Take on an empty stomach if possible.
Rifampin does not have clear concentration-related toxicity and most patients tolerate concentrations above the stated range without difficulty.
Hepatic dysfunction may produce elevated rifampin concentrations. Rifampin concentrations greater than 50% above the range may warrant a dose reduction of 150 to 300 mg.
If the time of the dose and the blood draw were not accurately recorded, accurate interpretation of the concentration is not possible.
Monday through Friday
The performance characteristics for this test have been validated by Advanced Diagnostic Laboratories at National Jewish Health. It has not been cleared or approved by the US Food and Drug Administration. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions. This laboratory is certified under the Clinical Laboratory Improvement Amendments of 1988 (CLIA 88) as qualified to perform high complexity clinical laboratory testing.
|Test Id||Test Order Name||Order LOINC Value|
|FRIFA||Rifampin Level||Not Provided|
|Result Id||Test Result Name||
Result LOINC Value
Applies only to results expressed in units of measure originally reported by the performing laboratory. These values do not apply to results that are converted to other units of measure.
|Z5804||Date and Time of Last Dose||Not Provided|
|Z5865||Specimen Type:||Not Provided|