Test Catalog

Test Id : FFCAH

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Congenital Adrenal Hyperplasia (CAH) Pediatric Profile 6, Comprehensive Screen

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Overview

Test Catalog

Method Name
A short description of the method used to perform the test

High Pressure Liquid Chromatography/Tandem Mass

Spectrometry (HPLC/MS-MS)

NY State Available
Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Reporting Name
Lists a shorter or abbreviated version of the Published Name for a test

CAH Profile 6

Aliases
Lists additional common names for a test, as an aid in searching

CAH Profile 6

CAH Profile 6-Comprehensive

Congenital Adrenal Hyperplasia, Comprehensive Screen

Specimen Type
Describes the specimen type validated for testing

Serum Red

Specimen Required
Defines the optimal specimen required to perform the test and the preferred volume to complete testing

Specimen Type: Serum

Container/Tube: Red

Specimen Volume: 3.5 mL

Collection Instructions: Draw blood in a plain, red-top tube(s). (Serum gel tube is not acceptable.) Spin down and separate within 1 hour of collection and send 3.5 mL of serum frozen in plastic vial.

Specimen Minimum Volume
Defines the amount of sample necessary to provide a clinically relevant result as determined by the Testing Laboratory

2 mL NOTE: Minimum volume does not allow for repeat analysis.

Reject Due To
Identifies specimen types and conditions that may cause the specimen to be rejected

Specimens other than Serum Red
Anticoagulants other than NA
Hemolysis Gross; Reject Mild: OK
Lipemia Gross Reject; Mild OK
Icteric NA

Specimen Stability Information
Provides a description of the temperatures required to transport a specimen to the performing laboratory, alternate acceptable temperatures are also included

Specimen Type Temperature Time Special Container
Serum Red Frozen (preferred) 90 days

Reference Values
Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

Androstenedione

 

Units:  ng/dL

 

Age              

Range

Premature (26-28w) Day 4    

63 - 935

Premature (31-35w) Day 4    

50 - 449

Full Term (1-7 days)                  

<10 - 279

 

Levels decrease rapidly to <52 ng/dL after one week.

 

 

1 - 11m

<10 - 37

 

Androstenedione gradually decreases during the first six months to prepubertal levels.

 

 

Prepubertal Children         

<10 - 17

Adult Males                          

44 - 186

Adult Females                    

28 - 230

Females Postmenopausal         

<10-93

 

 

 

Cortisol

 

Units:  ug/dL

 

Age

Range

Premature (26-28w) Day 4     

1.0 - 11

Premature (31-35w) Day 4     

2.5 -   9.1

Full Term Day 3                 

1.7 - 14

Full Term Day 7                           

2.0 - 11

31d - 11m

2.8 - 23

12m - 15y (8:00 AM)

3 .0 - 21

 

 

Adults

 

8:00 AM                   

8.0 - 19

4:00 PM                   

4.0 - 11

 

 

 

Deoxycorticosterone (DOC)

 

Units:  ng/dL

 

Age

Range

Premature (26 - 28w) Day 4         

20 - 105

Premature (34 - 36w) Day 4         

28 - 78

 

Newborn:  Levels are markedly elevated at birth and decrease rapidly during the first week to the range of 7 - 49 as found in older infants.

 

 

1 - 11m

7 - 49

Prepubertal Children  

2 - 34

Pubertal Children and Adults 8:00 AM                

2 - 19

 

 

 

Dehydroepiandrosterone (DHEA)

Units:  ng/dL

 

Age

Range

Premature (26 - 31w)                

82 - 1484

Premature (32 - 35w)

56 - 1853

Full Term (2 - 7d)

41 - 1292

8d - 5m

<948

6 - 12m

<136

1 - 5 y

<68

6 - 7 y

<111

8 - 10 y

<186

11 - 12 y

<202

13 - 14 y

<319

15 - 16 y

39 - 481

17 - 19 y          

40 - 491

20 - 49 y          

31 - 701

> or = 50 y

21 - 402      

 

 

 

11-Desoxycortisol

 

Units:  ng/dL

 

Age

Range

Premature (26-28w) Day 4

110 - 1376

Premature (31-35w) Day 4

48 - 579

Newborn Day 3     

13 - 147

1 - 11m

<10 - 156

Prepubertal 8:00 AM                     

20 - 155

Pubertal Children and Adults 8:00 AM           

12 - 158

 

 

 

17-OH Pregnenolone

 

Units:  ng/dL

 

Age

Range

Premature (26-28w) Day 4

375 - 3559

Premature (31-35w) Day 4

64 - 2380

3 Days

10 - 829

1 - 5m

36 - 763

6 - 11m

42 - 540

12 - 23m

14 - 207

24m  - 5y

10 - 103

6 - 9y

10 - 186

Pubertal

44 - 235

Adults

53 - 357

 

 

 

Progesterone

 

Units:  ng/dL

 

Males

 

Age

Range                    

1 - 16y

<10 - 15

Adults  

<10 - 11

 

 

Females

 

Age

Range                    

1-10y

<10 - 26

11y

<10 - 255

12y                                    

<10 - 856

13y

<10 - 693

14y

<10 - 1204

15y

<10 - 1076

16y

<10 -1294

 

 

Adult

 

Cycle Days

Range

1 - 6

<10 - 17

7 - 12

<10 - 135

13 - 15

<10 - 1563

16 - 28

<10 - 2555

Post Menopausal

<10

 

 

Note: Luteal progesterone peaked from 350 to 3750 ng/dL on days ranging from 17 to 23.

 

 

 

17-Alpha-Hydroxyprogesterone 17-OHP

 

Units:  ng/dL    

 

Age

Range            

Premature (26-28w) Day 4

124 - 841

Premature (31-35w) Day 4

26 - 568

Full-Term Day 3

<78

 

 

Males: Levels increase after the first week to peak values ranging from 40 - 200 between 30 and 60 days. Values then decline to a prepubertal value of <91 before one year.

 

 

Prepubertal              

<91

Adult Males                    

27 - 199

 

 

Females

 

1 - 11m

13 - 106

Prepubertal

<91

Adult Females

 

Follicular                     

15-70

Luteal                             

35-290

                          

 

 

Testosterone, Total

 

 

Units:  ng/dL         

 

 

Age

Range

 

Males                                 

 

 

Premature (26-28w) Day 4  

59 - 125

 

Premature (31-35w) Day 4

37 - 198

 

Newborns

75 - 400

 

 

 

 

1 - 7m:  Levels decrease rapidly the first week to 20 - 50, then increase to 60 - 400 between 20 - 60 days. Levels then decline to prepubertal range levels of <2.5 - 10 by seven months.

 

 

 

Females

 

 

Premature (26 - 28w) Day 4

5 - 16

 

Premature (31 - 35w) Day 4

5 - 22

 

Newborns

20 - 64

 

 

 

 

1 - 7m: Levels decrease during the first month to less than 10 and remain there until puberty.

 

 

 

Prepubertal Males and Females    

<2.5 - 10

 

Adult Males  >18 years                

264 - 916

 

Adult Females

 

 

Premenopausal

10 - 55

 

Postmenopausal

7 - 40

 

 

 

 

Males

 

 

Tanner Stage           

Age (years)             

Male

1

<9.8                

<2.5 - 10

2

9.8 - 14.5       

18 - 150

3

10.7 - 15.4        

100 - 320

4

11.8 - 16.2         

200 - 620

5

12.8 - 17.3          

350 - 970

 

 

 

Females

 

 

Tanner Stage          

Age (years)             

Female

1

<9.2               

<2.5 - 10

2

9.2 - 13.7                

7 - 28

3

10.0 - 14.4               

15 - 35

4

10.7 - 15.6               

13 - 32

5

11.8 - 18.6                

20 - 38

PDF Report
Indicates whether the report includes an additional document with charts, images or other enriched information

No

Day(s) Performed
Outlines the days the test is performed. This field reflects the day that the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time before the test is performed. Some tests are listed as continuously performed, which means that assays are performed multiple times during the day.

Monday, Wednesday

Report Available
The interval of time (receipt of sample at Mayo Clinic Laboratories to results available) taking into account standard setup days and weekends. The first day is the time that it typically takes for a result to be available. The last day is the time it might take, accounting for any necessary repeated testing.

4 to 14 days

Performing Laboratory Location
Indicates the location of the laboratory that performs the test

Esoterix Endocrinology

Fees
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  • Authorized users can sign in to Test Prices for detailed fee information.
  • Clients without access to Test Prices can contact Customer Service 24 hours a day, seven days a week.
  • Prospective clients should contact their Regional Manager. For assistance, contact Customer Service.

Test Classification
Provides information regarding the medical device classification for laboratory test kits and reagents. Tests may be classified as cleared or approved by the US Food and Drug Administration (FDA) and used per manufacturer instructions, or as products that do not undergo full FDA review and approval, and are then labeled as an Analyte Specific Reagent (ASR) product.

This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.

CPT Code Information
Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Clinic Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.

CPT codes are provided by the performing laboratory.

82633/DOC

82634/ 11-Desoxycortisol

82157/Androstenedione

82533/Cortisol

82626/DHEA

84143/17-OH-Pregnenolone

84144/Progesterone

83498/17-OH-Progesterone

84403/Testosterone

LOINC® Information
Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the order and results codes of this test. LOINC values are provided by the performing laboratory.

Test Id Test Order Name Order LOINC Value
FFCAH CAH Profile 6 Not Provided
Result Id Test Result Name Result LOINC Value
Applies only to results expressed in units of measure originally reported by the performing laboratory. These values do not apply to results that are converted to other units of measure.
Z5043 Cortisol 2143-6
Z5044 Deoxycorticosterone (DOC) 1656-8
Z5045 11-Desoxycortisol 1657-6
Z5046 Dehydroepiandrosterone (DHEA) 2193-1
Z5047 17-OH Pregnenolone 6765-2
Z5048 Progesterone 2839-9
Z5049 17-Alpha-Hydroxyprogesterone 17-OHP 1668-3
Z5050 Androstenedione 1854-9
Z5051 Testosterone, Total 2986-8

Test Setup Resources

Setup Files
Test setup information contains test file definition details to support order and result interfacing between Mayo Clinic Laboratories and your Laboratory Information System.

Excel | Pdf

Sample Reports
Normal and Abnormal sample reports are provided as references for report appearance.

Normal Reports | Abnormal Reports

SI Sample Reports
International System (SI) of Unit reports are provided for a limited number of tests. These reports are intended for international account use and are only available through MayoLINK accounts that have been defined to receive them.

SI Normal Reports | SI Abnormal Reports