Incorporating and summarizing results into an overall evaluation with consultative interpretation on the HBEL1 / Hemoglobin Electrophoresis Evaluation, Blood
This test is an additional consultative interpretation that summarizes all testing as well as any pertinent clinical information available for review, and will be provided after all reflexed tests have been completed. If performed, subsequent molecular results will also be incorporated into the overall evaluation. One or more of the following molecular tests may be reflexed on the HBEL1 / Hemoglobin Electrophoresis Evaluation, Blood:
-ATHAL / Alpha-Globin Gene Analysis, Varies
-WASQR / Alpha-Globin Gene Sequencing, Blood
-WBSQR / Beta-Globin Gene Sequencing, Blood
-WBDDR / Beta-Globin Cluster Locus Deletion/Duplication, Blood
-WGSQR / Gamma-Globin Full Gene Sequencing, Varies
This summary is in addition to interpretations that may be provided for each component.
Only orderable as a reflex. For more information see HBEL1 / Hemoglobin Electrophoresis Evaluation, Blood.
Medical Interpretation.
This test is an additional consultative interpretation that summarizes all testing as well as any pertinent clinical information available for review, and will be provided after all reflexed tests have been completed. If performed, subsequent molecular results will also be incorporated into the overall evaluation. One or more of the following molecular tests may be reflexed on the HBEL1 / Hemoglobin Electrophoresis Evaluation, Blood:
-ATHAL / Alpha-Globin Gene Analysis, Varies
-WASQR / Alpha-Globin Gene Sequencing, Blood
-WBSQR / Beta-Globin Gene Sequencing, Blood
-WBDDR / Beta-Globin Cluster Locus Deletion/Duplication, Blood
-WGSQR / Gamma-Globin Full Gene Sequencing, Varies
This summary is in addition to interpretations that may be provided for each component.
Whole Blood EDTA
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Whole Blood EDTA | Refrigerated |
Incorporating and summarizing results into an overall evaluation with consultative interpretation on the HBEL1 / Hemoglobin Electrophoresis Evaluation, Blood
This test is an additional consultative interpretation that summarizes all testing as well as any pertinent clinical information available for review, and will be provided after all reflexed tests have been completed. If performed, subsequent molecular results will also be incorporated into the overall evaluation. One or more of the following molecular tests may be reflexed on the HBEL1 / Hemoglobin Electrophoresis Evaluation, Blood:
-ATHAL / Alpha-Globin Gene Analysis, Varies
-WASQR / Alpha-Globin Gene Sequencing, Blood
-WBSQR / Beta-Globin Gene Sequencing, Blood
-WBDDR / Beta-Globin Cluster Locus Deletion/Duplication, Blood
-WGSQR / Gamma-Globin Full Gene Sequencing, Varies
This summary is in addition to interpretations that may be provided for each component.
The evaluation of hemoglobin disorders can be very complex. This can involve abnormalities in the alpha, beta, delta, or gamma chains. Molecular testing is performed to fully evaluate complex situations. A summary interpretation that incorporates all of the testing performed is beneficial to the ordering physician.
Only orderable as a reflex. For more information see HBEL1 / Hemoglobin Electrophoresis Evaluation, Blood.
An interpretive report will be provided.
An interpretive report will be provided that summarizes all testing as well as any pertinent clinical information.
No significant cautionary statements.
1. Hoyer JD, Hoffman DR: The thalassemia and hemoglobinopathy syndromes. In: McClatchey KD, ed. Clinical Laboratory Medicine. 2nd ed. Lippincott Williams and Wilkins; 2002:866-895
2. Harteveld CL, Higgs DR: Alpha-thalassemia. Orphanet J Rare Dis. 2010;5:13
3. Thein SL: The molecular basis of beta-thalassemia. Cold Spring Harb Persepct Med. 2013;1;3(5):a011700
4. Crowley MA, Mollan TL, Abdulmalik OY, et al: A hemoglobin variant associated with neonatal cyanosis and anemia. N Engl J Med. 2011;364:1837-1843
5. Kipp BR, Roellinger SE, Lundquist PA, et al: Development and clinical implementation of a combination deletion PCR and multiplex ligation-dependent probe amplification assay for detecting deletions involving the human alpha-globin gene cluster. J Mol Diagn. 2011 Sep;13(5):549-557. doi: 10.1016/j.jmoldx.2011.04.001
6. Hein MS, Oliveira JL, Swanson KC, et al: Large deletions involving the beta globin gene complex: genotype-phenotype correlation of 119 cases. Blood. 2015;126:3374
A hematopathologist evaluates all of the testing performed and a summary interpretive report is added.
Monday through Friday
Not Applicable
83020-26
Test Id | Test Order Name | Order LOINC Value |
---|---|---|
HBEL0 | Hb Electrophoresis Summary Interp | In Process |
Result Id | Test Result Name |
Result LOINC Value
Applies only to results expressed in units of measure originally reported by the performing laboratory. These values do not apply to results that are converted to other units of measure.
|
---|---|---|
608091 | Hb Electrophoresis Summary Interp | 13514-5 |
608117 | Reviewed By | 18771-6 |