Interpretation of the detection and quantitation of inhibitor to coagulation factor XI
This test is not useful for the detection of a lupus-like circulating anticoagulant inhibitor, a nonspecific circulating anticoagulant, or other inhibitors that are not specific for coagulation factors.
If the factor XI activity assay is normal or elevated, a computer-generated interpretive comment will be provided indicating inhibitor testing is not indicated and will not be performed.
Only orderable as part of a profile. For more information see 11INE / Factor XI Inhibitor Evaluation, Plasma
Technical Interpretation
Factor XI Inhibitor Screen, Plasma
If the factor XI activity assay is normal or elevated, a computer-generated interpretive comment will be provided indicating inhibitor testing is not indicated and will not be performed.
Plasma Na Cit
Only orderable as part of a profile. For more information see 11INE / Factor XI Inhibitor Evaluation, Plasma
Gross hemolysis | Reject |
Gross lipemia | Reject |
Gross icterus | Reject |
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Plasma Na Cit | Frozen | 14 days |
Interpretation of the detection and quantitation of inhibitor to coagulation factor XI
This test is not useful for the detection of a lupus-like circulating anticoagulant inhibitor, a nonspecific circulating anticoagulant, or other inhibitors that are not specific for coagulation factors.
If the factor XI activity assay is normal or elevated, a computer-generated interpretive comment will be provided indicating inhibitor testing is not indicated and will not be performed.
Factor XI inhibitors typically arise in patients with congenital XI deficiency (hemophilia C) or after infusion of fresh frozen plasma or factor XI concentrates. Acquired factor XI inhibitors rarely occur spontaneously.
Only orderable as part of a profile. For more information see 11INE / Factor XI Inhibitor Evaluation, Plasma
An interpretive report will be provided.
Occasionally, a potent lupus-like anticoagulant may cause false-positive testing for a specific factor inhibitor (eg, factor VIII or IX).
1. Hematology: Basic Principles and Practice. Seventh edition. Edited by R Hoffman, EJ Benz Jr, LE Silberstein, et al. Elsevier, 2018
2. Kasper CK: Treatment of factor VIII inhibitors. Prog Hemost Thromb 1989;9:57-86
3. Laboratory Hematology Practice. Edited by K Kottke-Marchant. Wiley Blackwell Publishing, 2012
If the factor XI activity level is normal or elevated, a computer-generated interpretive comment indicating inhibitor testing was not indicated and was not performed will be provided.(Unpublished Mayo method).
Monday through Friday
Not Applicable
85390
Test Id | Test Order Name | Order LOINC Value |
---|---|---|
11INT | FXI Inhib Profile Tech Interp | 69049-5 |
Result Id | Test Result Name |
Result LOINC Value
Applies only to results expressed in units of measure originally reported by the performing laboratory. These values do not apply to results that are converted to other units of measure.
|
---|---|---|
11INT | FXI Inhib Profile Tech Interp | 69049-5 |