Detection and quantitation of inhibitor to factor II
This test is not useful for the detection of a lupus-like circulating anticoagulant inhibitor, a nonspecific circulating anticoagulant, or other inhibitors that are not specific for coagulation factors.
If the factor II activity assay is normal or elevated, a computer-generated interpretive comment will be provided indicating inhibitor testing is not indicated and will not be performed.
Only orderable as part of a profile. For more information see 2INHE / Factor II Inhibitor Evaluation, Plasma
Technical Interpretation
Factor II Inhibitor Screen, Plasma
If the factor II activity assay is normal or elevated, a computer-generated interpretive comment will be provided indicating inhibitor testing is not indicated and will not be performed.
Plasma Na Cit
Only orderable as part of a profile. For more information see 2INHE / Factor II Inhibitor Evaluation, Plasma
Gross Hemolysis | Reject |
Gross Lipemia | Reject |
Gross Icterus | Reject |
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Plasma Na Cit | Frozen | 14 days |
Detection and quantitation of inhibitor to factor II
This test is not useful for the detection of a lupus-like circulating anticoagulant inhibitor, a nonspecific circulating anticoagulant, or other inhibitors that are not specific for coagulation factors.
If the factor II activity assay is normal or elevated, a computer-generated interpretive comment will be provided indicating inhibitor testing is not indicated and will not be performed.
Coagulation factor inhibitors arise in patients who are congenitally deficient in a specific factor in response to factor replacement therapy or can either occur spontaneously without known cause or in response to a variety of medical conditions including the postpartum state, immunologic disorders, certain antibiotic therapies, some malignancies, and in geriatric patients.
Inhibitors of factor VIII coagulant activity are the most commonly occurring of the specific factor inhibitors.
Only orderable as part of a profile. For more information see 2INHE / Factor II Inhibitor Evaluation, Plasma
An interpretive report will be provided.
Occasionally, a potent lupus-like anticoagulant may cause false-positive testing for a specific factor inhibitor (eg, factor VIII or IX).
1. Hematology: Basic Principles and Practice. Seventh edition. Edited by R Hoffman, EJ Benz Jr, LE Silberstein, et al. Elsevier, 2018
2. Kasper CK: Treatment of factor VIII inhibitors. Prog Hemost Thromb 1989;9:57-86
3. Laboratory Hematology Practice. Edited by K Kottke-Marchant. Wiley Blackwell Publishing, 2012
If the factor II activity level is normal or elevated, a computer-generated interpretive comment indicating inhibitor testing was not indicated and was not performed will be provided.(Unpublished Mayo method)
Not Applicable
85390
Test Id | Test Order Name | Order LOINC Value |
---|---|---|
2INHT | FII Inhib Profile Tech Interp | 69049-5 |
Result Id | Test Result Name |
Result LOINC Value
Applies only to results expressed in units of measure originally reported by the performing laboratory. These values do not apply to results that are converted to other units of measure.
|
---|---|---|
2INHT | FII Inhib Profile Tech Interp | 69049-5 |