Interpretation of the detecting and quantifying the presence and titer of a specific factor inhibitor directed against a specific coagulation factor
If the factor V activity assay is normal or elevated, then a computer-generated interpretive comment will be provided indicating inhibitor testing is not indicated and will not be performed.
Only orderable as part of a profile. For more information see 5INHE / Factor V Inhibitor Evaluation, Plasma.
Technical Interpretation
Factor V Inhibitor Screen, Plasma
If the factor V activity assay is normal or elevated, then a computer-generated interpretive comment will be provided indicating inhibitor testing is not indicated and will not be performed.
Plasma Na Cit
Only orderable as part of a profile. For more information see 5INHE / Factor V Inhibitor Evaluation, Plasma.
Gross hemolysis | Reject |
Gross lipemia | Reject |
Gross icterus | Reject |
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Plasma Na Cit | Frozen | 14 days |
Interpretation of the detecting and quantifying the presence and titer of a specific factor inhibitor directed against a specific coagulation factor
If the factor V activity assay is normal or elevated, then a computer-generated interpretive comment will be provided indicating inhibitor testing is not indicated and will not be performed.
Significant bleeding can result from the presence of a coagulation factor inhibitor and could be life threatening. Whether the inhibitor is present due to hemophilia or of an acquired nature, it greatly complicates the treatment process of a decreased factor level. The titer of the inhibitor may determine the mode of treatment. Bethesda units are a standardization to give a uniform definition of an inhibitor.
Only orderable as part of a profile. For more information see 5INHE / Factor V Inhibitor Evaluation, Plasma.
An interpretive report will be provided.
Occasionally, a potent lupus-like anticoagulant may cause false-positive testing for a specific factor inhibitor (eg, factor VIII or IX).
1. Biggs R, Bidwell E: A method for the study of antihemophiliac globulin inhibitors with reference to six cases. Br J Haematol 1959;5:379-395
2. Hoyer LW: Factor VIII inhibitors In Progress in Clinical and Biological Research. Vol 150. Edited by LW Hoyer, R Alan Liss Inc, 1984, pp 87-98
3. Kasper CK, Aledort L, Aronson D, et al: A more uniform measurement of factor VIII inhibitors. Thromb Diath Haemorrh 1975;34:612
4. Kasper C, Ewing N: Acquired inhibitors of plasma coagulation factors. J Med Tech 1986;38:431-439
5. Laboratory Hematology Practice. Edited by K Kottke-Marchant. Wiley Blackwell Publishing. 2012
If the factor V activity level is normal or elevated, a computer-generated interpretive comment indicating inhibitor testing was not indicated and was not performed will be provided.(Unpublished Mayo method)
Monday through Friday
Not Applicable
85390
Test Id | Test Order Name | Order LOINC Value |
---|---|---|
5INHT | FV Inhib Profile Tech Interp | 69049-5 |
Result Id | Test Result Name |
Result LOINC Value
Applies only to results expressed in units of measure originally reported by the performing laboratory. These values do not apply to results that are converted to other units of measure.
|
---|---|---|
5INHT | FV Inhib Profile Tech Interp | 69049-5 |