Test Id : FUNBL
Fungitell, BAL
    
        Method Name
            
                
                
                    
                    A short description of the method used to perform the test
                
            
    
    Limulus Amebocyte Lysate (LAL) Pathway
    
        NY State Available
            
                
                
                    
                    Indicates the status of NY State approval and if the test is orderable for NY State clients.
                
            
    
    
    
        Reporting Name
            
                
                
                    
                    Lists a shorter or abbreviated version of the Published Name for a test
                
            
    
    
    
        Aliases
            
                
                
                    
                    Lists additional common names for a test, as an aid in searching
                
            
    
    BDG
Beta D Glucan
Beta-D glucan
Beta-D-Glucan
    
        Specimen Type
            
                
                
                    
                    Describes the specimen type validated for testing
                
            
    
        Lavage
    
        Specimen Required
            
                
                
                    
                    Defines the optimal specimen required to perform the test and the preferred volume to complete testing
                
            
    
    Specimen Type: Bronchoalveolar lavage
Container/Tube: Sterile container
Specimen Volume: 1 to 3 mL
Collection Instructions:
1. Collect 1 to 3 mL bronchial lavage in a sterile container.
2.Ship frozen
    
        Specimen Minimum Volume
            
                
                
                    
                    Defines the amount of sample necessary to provide a clinically relevant result as determined by the testing laboratory. The minimum volume is sufficient for one attempt at testing.
                
            
    
    0.5 mL
    
        Reject Due To
            
                
                
                    
                    Identifies specimen types and conditions that may cause the specimen to be rejected
                
            
    
    | Hemolysis | Reject | 
| Lipemia | Reject | 
| Icterus | Reject | 
| Universal transport media | Reject | 
    
        Specimen Stability Information
            
                
                
                    
                    Provides a description of the temperatures required to transport a specimen to the performing laboratory, alternate acceptable temperatures are also included
                
            
    
    | Specimen Type | Temperature | Time | Special Container | 
|---|---|---|---|
| Lavage | Frozen (preferred) | 30 days | |
| Ambient | 4 days | ||
| Refrigerated | 7 days | 
    
        Clinical Information
            
                
                
                    
                    Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test
                
            
    
    The Fungitell beta-D glucan assay detects (1,3)-beta-D-glucan from the following pathogens: Candida spp., Acremonium, Aspergillus spp., Coccidioides immitis, Fusarium spp., Histoplasma capsulatum, Trichosporon spp., Sporothrix schenckii, Saccharomyces cerevisiae, and Pneumocystis jiroveci.
 
The Fungitell beta-D glucan assay does not detect certain fungal species, such as the genus Cryptococcus, which produces very low levels of (1,3)-beta-D-glucan, nor the Zygomycetes such as Absidia, Mucor, and Rhizopus, which are not known to produce (1,3)-beta-D-glucan. Studies indicate Blastomyces dermatitidis is usually not detected due to little (1,3)-beta-D-glucan produced in the yeast phase.
    
        Reference Values
            
                
                
                    
                    Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.
                
            
    
    A reference range for specimens other than serum has not been established.
    
        Interpretation
            
                
                
                    
                    Provides information to assist in interpretation of the test results
                
            
    
    The performance characteristics of the Fungitell assay in bronchoalveolar lavage (BAL have been determined by Eurofins Viracor; there are no established criteria for the interpretation of Fungitell results from BAL fluid. Research studies have evaluated the use of the Fungitell assay in BAL in both immunocompromised patients (1) and acute eosinophilic pneumonia.(2)
    
        Clinical Reference
            
                
                
                    
                    Recommendations for in-depth reading of a clinical nature
                
            
    
    1. Theel ES, Jespersen DJ, Iqbal S, et al. Detection of (1, 3)-ß-D-glucan in bronchoalveolar lavage and serum samples collected from immunocompromised hosts. Mycopathologia. 2013;175(1-2):33-41. doi:10.1007/s11046-012-9579-y
2. Kawayama T, Fujiki R, Honda J, Rikimaru T, Aizawa H. High concentration of (1-->3)-beta-D-glucan in BAL fluid in patients with acute eosinophilic pneumonia. Chest. 2003;123(4):1302-1307. doi:10.1378/chest.123.4.1302
    
        PDF Report
            
                
                
                    
                    Indicates whether the report includes an additional document with charts, images or other enriched information
                
            
    
    
    
        Day(s) Performed
            
                
                
                    
                    Outlines the days the test is performed. This field reflects the day that the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time before the test is performed. Some tests are listed as continuously performed, which means that assays are performed multiple times during the day.
                
            
    
    Monday through Saturday
    
        Report Available
            
                
                
                    
                    The interval of time (receipt of sample at Mayo Clinic Laboratories to results available) taking into account standard setup days and weekends. The first day is the time that it typically takes for a result to be available. The last day is the time it might take, accounting for any necessary repeated testing.
                
            
    
    
    
        Performing Laboratory Location
            
                
                
                    
                    Indicates the location of the laboratory that performs the test
                
            
    
    
    
        Fees :
            
                
                
                    
                    Several factors determine the fee charged to perform a test. Contact your U.S. or International Regional Manager for information about establishing a fee schedule or to learn more about resources to optimize test selection.
                
            
    
    - Authorized users can sign in to Test Prices for detailed fee information.
- Clients without access to Test Prices can contact Customer Service 24 hours a day, seven days a week.
- Prospective clients should contact their account representative. For assistance, contact Customer Service.
    
        CPT Code Information
            
                
                
                    
                    Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Clinic Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.
CPT codes are provided by the performing laboratory.
                
            
    
    CPT codes are provided by the performing laboratory.
87449
    
        LOINC® Information
            
                
                
                    
                    Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the order and results codes of this test. LOINC values are provided by the performing laboratory.
                
            
    
    | Test Id | Test Order Name | Order LOINC Value | 
|---|---|---|
| FUNBL | Fungitell, BAL | Not Provided | 
| Result Id | Test Result Name | Result LOINC Value 
                                        
                                        Applies only to results expressed in units of measure originally reported by the performing laboratory. These values do not apply to results that are converted to other units of measure.
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|---|---|---|
| FUNBL | Fungitell, BAL | Not Provided |