TEST CATALOG ORDERING & RESULTS SPECIMEN HANDLING CUSTOMER SERVICE EDUCATION & INSIGHTS
Test Catalog

Test ID: CHIMS    
Chimerism Transplant Sorted Cells, Varies

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

Initial Chimerism Testing:

Complete chimerism analysis requires 3 specimens. These specimens should be submitted when collected. An interpretive report will be provided once all specimens are received.

 

-CHRGB / Chimerism-Recipient Germline (Pretransplant), Varies

-CHIDB / Chimerism-Donor, Varies

-CHIMS / Chimerism Transplant Sorted Cells, Varies

 

Billing occurs with tests CHRGB (for the Pre and Donor specimens) and SORT1 / Chimerism Cell Sort 1 (Bill Only) and/or SORT2 / Chimerism Cell Sort 2 (Bill Only) (for the Post specimen). If an additional donor specimen is submitted, ADONO / Additional Chimerism Donor (Bill Only) will be performed at an additional charge.

 

Chimerism Transplant Cell Sort:

When this test is ordered SORT1 / Chimerism Cell Sort 1 (Bill Only) and/or SORT2 / Chimerism Cell Sort 2 (Bill Only) will be performed at an additional charge.

 

See Chimerism-Recipient Germline Testing Algorithm in Special Instructions.

Specimen Type Describes the specimen type validated for testing

Varies

Ordering Guidance

This test is used to determine the relative amounts of donor and recipient cells in a specimen post-bone marrow transplant. For post-bone marrow transplant evaluation of the donor specimen, see CHIMU / Chimerism Transplant No Cell Sort, Varies.

Additional Testing Requirements

Complete chimerism analysis also requires submission of CHRGB / Chimerism-Recipient Germline (Pretransplant), Varies and CHIDB / Chimerism-Donor, Varies specimens. These tests must be ordered on both the pretransplant and donor specimens under separate order numbers. While the 3 specimens do not need to be submitted at the same time, the CHRGB and CHIDB specimens must be received before this test can be performed.

Shipping Instructions

Specimen must arrive within 96 hours of collection. Collect and package specimen as close to shipping time as possible.

Necessary Information

The following information is required:

1. Pertinent clinical history

2. Specimen source

3. Donor identifier and donor date of birth

4. Donor date of collection

Specimen Required Defines the optimal specimen required to perform the test and the preferred volume to complete testing

Submit only 1 of the following specimens:

 

Specimen Type: Blood

Container/Tube:

Preferred: Lavender top (EDTA)

Acceptable: Yellow top (ACD)

Specimen Volume: 4 mL

Collection Instructions:

1. Only 1 tube is required.

2. Invert several times to mix blood.

3. Send specimen in original tube. Do not aliquot.

4. Label specimen as blood.

 

Specimen Type: Bone marrow

Container/Tube:

Preferred: Lavender top (EDTA)

Acceptable: Yellow top (ACD)

Specimen Volume: 2 mL

Collection Instructions:

1. Invert several times to mix bone marrow.

2. Send specimen in original tube. Do not aliquot.

3. Label specimen as bone marrow.

Special Instructions Library of PDFs including pertinent information and forms related to the test

Forms

1. Chimerism Analysis Information Sheet (T594) in Special Instructions.

2. If not ordering electronically, complete, print, and send a Hematopathology/Cytogenetics Test Request (T726) with the specimen.

Specimen Minimum Volume Defines the amount of sample necessary to provide a clinically relevant result as determined by the Testing Laboratory

Blood: 3 mL
Bone Marrow: 2 mL
Lesser volumes may be acceptable, depending on white cell count.

Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected

Gross hemolysis Reject
Moderately to severely clotted Reject

Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the performing laboratory, alternate acceptable temperatures are also included

Specimen TypeTemperatureTimeSpecial Container
VariesAmbient (preferred)4 daysPURPLE OR PINK TOP/EDTA
 Refrigerated 4 daysPURPLE OR PINK TOP/EDTA