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Test Catalog

Test ID: JAKXM    
JAK2 Exon 12 and Other Non-V617F Mutation Detection, Bone Marrow

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

This is a second-order test that should be used when the test for the JAK2M / JAK2 V617F Mutation Detection, Bone Marrow test is negative.

 

See Myeloproliferative Neoplasm: A Diagnostic Approach to Bone Marrow Evaluation in Special Instructions.

Specimen Type Describes the specimen type validated for testing

Bone Marrow

Ordering Guidance

In all cases being evaluated for JAK2 mutation status, the initial test that should be ordered is JAK2M / JAK2 V617F Mutation Detection, Bone Marrow, a sensitive assay for detection of the mutation. However, if no JAK2 V617F mutation is found, further evaluation of JAK2 may be clinically indicated.

 

This test is a second-order test that should be ordered when the test for the JAK2M / JAK2 V617F Mutation Detection, Bone Marrow test is negative.

Shipping Instructions

1. Specimen must arrive within 5 days (120 hours) of collection.

2. Draw and package specimen as close to shipping time as possible.

Necessary Information

Date of collection is required.

Specimen Required Defines the optimal specimen required to perform the test and the preferred volume to complete testing

Container/Tube:

Preferred: EDTA (lavender top)

Acceptable: ACD (yellow top)

Specimen Volume: 4 mL

Collection Instructions:

1. Invert several times to mix bone marrow.

2. Send specimen in original tube.

Special Instructions Library of PDFs including pertinent information and forms related to the test

Forms

1. Hematopathology Patient Information (T676) in Special Instructions

2. If not ordering electronically, complete, print, and send a Hematopathology/Cytogenetics Test Request (T726) with the specimen.

Specimen Minimum Volume Defines the amount of sample necessary to provide a clinically relevant result as determined by the Testing Laboratory

2 mL

Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected

Gross hemolysis Reject
Other Moderately to severely clotted

Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the performing laboratory, alternate acceptable temperatures are also included

Specimen TypeTemperatureTimeSpecial Container
Bone MarrowRefrigerated (preferred)5 daysPURPLE OR PINK TOP/EDTA
 Ambient 5 daysPURPLE OR PINK TOP/EDTA