TEST CATALOG ORDERING & RESULTS SPECIMEN HANDLING CUSTOMER SERVICE EDUCATION & INSIGHTS
Test Catalog

Test ID: CHRAF    
Chromosome Analysis, Amniotic Fluid

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

This test includes a charge for cell culture of fresh specimens and professional interpretation of results. Analysis charges will be incurred for total work performed, and generally include 2 banded karyograms and the analysis of 20 metaphase cells. If no metaphase cells are available for analysis, no analysis charges will be incurred. If additional analysis work is required, additional charges may be incurred.

 

The following algorithms are available in Special Instructions:

-Prenatal Aneuploidy Screening and Diagnostic Testing Options

-High-Risk Pregnancy Based on Fetal Malformations or Positive Serum Screen: Laboratory Testing Algorithm

Specimen Type Describes the specimen type validated for testing

Amniotic Fld

Advisory Information

Portions of the specimen may be used for other tests such as measuring markers for neural tube defects (eg, AFPA / Alpha-Fetoprotein, Amniotic Fluid), molecular genetic testing, biochemical testing, and FISH testing (including PADF / Prenatal Aneuploidy Detection, FISH). If additional molecular genetic or biochemical genetic testing is needed, order CULAF / Amniotic Fluid Culture/Genetic Testing so that amniocyte cultures may be set up specifically for the use in these tests.

Shipping Instructions

Advise Express Mail or equivalent if not on courier service.

Necessary Information

Provide a reason for referral and gestational age with each specimen, and verify the specimen source. The laboratory will not reject testing if this information is not provided, but appropriate testing and interpretation may be compromised or delayed.

Specimen Required Defines the optimal specimen required to perform the test and the preferred volume to complete testing

Supplies: Refrigerate/Ambient Shipping Box, 5 lb (T329)

Specimen Type: Amniotic fluid

Submission Container/Tube: Centrifuge tube

Specimen Volume: 20-25 mL

Collection Instructions:

1. Optimal timing for specimen collection is during 14 to 18 weeks of gestation, but specimens collected at other weeks of gestation are also accepted.

2. Discard the first 2 mL of amniotic fluid.

3. Place the tubes in a Refrigerate/Ambient Shipping Box, 5 lb (T329).

4. Fill remaining space with packing material.

Additional Information:

1. Unavoidably, about 1% to 2% of mailed-in specimens are not viable.

2. If the specimen does not grow in culture, you will be notified within 7 days of receipt.

3. Bloody specimens are undesirable.

 

Supplies: Refrigerate/Ambient Shipping Box, 5 lb (T329)

Specimen Type: Fetal body fluid

Container/Tube: Sterile tube

Specimen Volume: Entire specimen

Collection Instructions:

1. Place the tubes in a Refrigerate/Ambient Shipping Box, 5 lb (T329).

2. Fill remaining space with packing material.

Additional Information:

1. If the specimen does not grow in culture, you will be notified within 7 days of receipt.

2. Clearly indicate on tube and paperwork that specimen is fetal body fluid.

Special Instructions Library of PDFs including pertinent information and forms related to the test

Forms

New York Clients-Informed consent is required. Document on the request form or electronic order that a copy is on file. The following documents are available in Special Instructions:

-Informed Consent for Genetic Testing (T576)

-Informed Consent for Genetic Testing-Spanish (T826)

Specimen Minimum Volume Defines the amount of sample necessary to provide a clinically relevant result as determined by the Testing Laboratory

Amniotic Fluid: 12 mL; Fetal Body Fluid: NA; If ordering in conjunction with other testing: If ordered with PADF: 14 mL, with CMAP: 24 mL, with PADF and CMAP: 26 mL

Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected

All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the performing laboratory, alternate acceptable temperatures are also included

Specimen TypeTemperatureTimeSpecial Container
Amniotic FldRefrigerated (preferred)
 Ambient