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Test Catalog

Test ID: GID2    
Autoimmune Gastrointestinal Dysmotility Evaluation, Serum

Useful For Suggests clinical disorders or settings where the test may be helpful

Investigating unexplained weight loss, early satiety, anorexia, nausea, vomiting, constipation or diarrhea in a patient with past or family history of cancer or autoimmunity

 

Directing a focused search for cancer

 

Investigating gastrointestinal symptoms that appear in the course or wake of cancer therapy, not explainable by recurrent cancer, metastasis or therapy; detection of autoantibodies on this profile helps differentiate autoimmune gastrointestinal dysmotility from the effects of chemotherapy

 

Detecting early evidence of cancer recurrence in previously seropositive patients who have a rising titer of 1 or more autoantibodies

Profile Information A profile is a group of laboratory tests that are ordered and performed together under a single Mayo Test ID. Profile information lists the test performed, inclusive of the test fee, when a profile is ordered and includes reporting names and individual availability.

Test IDReporting NameAvailable SeparatelyAlways Performed
AGIDIGI Dysmotility, Interpretation, SNoYes
ARBIACh Receptor (Muscle) Binding AbYesYes
GANGAChR Ganglionic Neuronal Ab, SNoYes
ANN1SAnti-Neuronal Nuclear Ab, Type 1NoYes
DPPISDPPX Ab IFA, SNoYes
GD65SGAD65 Ab Assay, SYesYes
VGKCNeuronal (V-G) K+ Channel Ab, SNoYes
CCNN-Type Calcium Channel AbNoYes
STRStriational (Striated Muscle) Ab, SYesYes

Reflex Tests Lists tests that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial tests.

Test IDReporting NameAvailable SeparatelyAlways Performed
ARMOACh Receptor (Muscle) Modulating AbNoNo
AMPCSAMPA-R Ab CBA, SNoNo
AMPISAMPA-R Ab IF Titer Assay, SNoNo
AMPHSAmphiphysin Ab, SNoNo
ABLOTAmphiphysin Western Blot, SNoNo
ANN2SAnti-Neuronal Nuclear Ab, Type 2NoNo
ANN3SAnti-Neuronal Nuclear Ab, Type 3NoNo
CS2CSCASPR2-IgG CBA, SNoNo
CRMWSCRMP-5-IgG Western Blot, SYesNo
CRMSCRMP-5-IgG, SNoNo
DPPCSDPPX Ab CBA, SNoNo
DPPTSDPPX Ab IFA Titer, SNoNo
GABCSGABA-B-R Ab CBA, SNoNo
GABISGABA-B-R Ab IF Titer Assay, SNoNo
LG1CSLGI1-IgG CBA, SNoNo
NMDCSNMDA-R Ab CBA, SNoNo
NMDISNMDA-R Ab IF Titer Assay, SNoNo
WBNParaneoplastic Autoantibody WBlot,SNoNo
PCABPPurkinje Cell Cytoplasmic Ab Type 1NoNo
PCAB2Purkinje Cell Cytoplasmic Ab Type 2NoNo
PCATRPurkinje Cell Cytoplasmic Ab Type TrNoNo

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

If indirect immunofluorescence assay (IFA) (ANN1S) pattern is indeterminate, then paraneoplastic autoantibody Western blot is performed at an additional charge.

 

If IFA patterns suggest collapsin response-mediator protein-5-IgG (CRMP-5-IgG), then CRMS or CRMP-5-IgG Western blot is performed at an additional charge.

 

If IFA patterns suggest amphiphysin antibody, then amphiphysin titer and/or amphiphysin Western blot is performed at an additional charge.

 

If IFA pattern suggests antineuronal nuclear antibody (ANNA) type 2 or type 3, Purkinje cell cytoplasmic antibody type 1, type 2, or type trace, and/or anti-glial nuclear antibody type 1, then ANN2S, ANN3S, PCABP, PCAB2, PCATR, and/or AGN1S is performed at an additional charge.

 

If IFA pattern suggests NMDA-R, then NMDA-R cell-binding assay (CBA) and NMDA-R titer are performed at an additional charge.

 

If IFA pattern suggests AMPA-R, then AMPA-R CBA and AMPA-R titer are performed at an additional charge.

 

If IFA pattern suggests GABA-B-R, then GABA-B-R CBA and GABA-B-R titer are performed at an additional charge.

 

If IFA pattern suggests DPPX antibody, then DPPX CBA and DPPX titer are performed at an additional charge.

 

If IFA pattern suggests mGluR1 antibody, then mGluR1 CBA and mGluR1 titer are performed at an additional charge.

 

If acetylcholine (ACh) receptor binding antibody is >0.02 nmol/L, then ACh receptor modulating antibodies and CRMP-5-IgG Western blot are performed at an additional charge.

 

If VGKC is above 0.00 nmol/L, then LGI1-IgG CBA and CASPR2-IgG CBA are performed at an additional charge.

 

See Autoimmune Gastrointestinal Dysmotility Evaluation Algorithm in Special Instructions.

Special Instructions Library of PDFs including pertinent information and forms related to the test

Method Name A short description of the method used to perform the test

ANN1S, ANN2S, ANN3S, PCABP, PCAB2, PCATR, AMPHS, CRMS, DPPIS, DPPTS, AMPIS, GABIS, NMDIS: Indirect Immunofluorescence Assay (IFA)

AMPCS, GABCS, NMDCS, LG1CS, CS2CS, DPPCS: Cell Binding Assay (CBA)

ARMO: Live Cell Assay (LCA)

ABLOT, CRMWS, WBN: Western Blot (WB)

CCN, ARBI, GANG, VGKC: Radioimmunoassay (RIA)

GD65S: Immunoprecipitation Assay (IPA)

STR: Enzyme Immunoassay (EIA)

NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Reporting Name Lists a shorter or abbreviated version of the Published Name for a test

Autoimmune GI Dysmotility Eval, S

Aliases Lists additional common names for a test, as an aid in searching

Acetylcholine Receptor (Muscle AChR) Antibodies
AChR (Acetylcholine Receptor)
ANNA (Antineuronal Nuclear Antibody)
Anti-CV2
Anti-Enteric Neuronal Antibody
Anti-GAD65 (Anti-Glutamic Acid Decarboxylase)
Anti-Hu
Anti-Skeletal Muscle Antibodies
Antineuronal
Calcium Channel Blockers
Cantoxin (Receptor Antibodies)
Cerebellar Antibodies
Chorea
Collapsin Response-Mediator Protein-5 Antibody (CRMP-5), Serum
Cramp-Fasciculation
CRMP-5, IgG
DPPX
dipeptidyl aminopeptidase-like protein 6
Dorsal Root Ganglion Antibody
Glutamate Decarboxylase Antibodies (GAD65)
Hu Antibody
Isaacs Disease
Motor End-Plate Antibody
Motor Nerve Terminal Antibodies
Muscle (Skeletal) Antibodies
Muscle Culture Antibodies
Myoid Antibody
N-Type Calcium Channel Antibody
Neuromuscular Hyperexcitability
Neuromyotonia
Neuronal Ganglionic Acetylcholine Receptor Antibody
Neuronal Nuclear Antibody Panel
Neuronal Potassium Channel Ab
Neuronal-Anti
P/Q Type Calcium Channel Antibody
Paraneoplastic Antibodies
Paraneoplastic Autoantibody Evaluation
Paraneoplastic Neurological Autoimmunity
Potassium Channel Antibodies (specify)
Stiff-man Syndrome
Striational (Striated Muscle) Antibodies
VGCC (Voltage-Gated Calcium Channel) Antibodies
VGKC
VGPC