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Values are valid only on day of printing. |
Preferred confirmation test for the diagnosis of aminolevulinic acid dehydratase deficiency porphyria
This test is not useful for detecting lead intoxication.
Aminolevulinic acid dehydratase (ALAD) activity can be inhibited in situations including hereditary tyrosinemia type 1, lead intoxication, and exposure to styrene, trichloroethylene, or bromobenzene. These causes should be ruled out when considering a diagnosis of ALAD deficiency porphyria (ADP). This method will not exhibit a decreased ALAD enzyme activity due to lead intoxication.
The following algorithms are available in Special Instructions:
-Porphyria (Acute) Testing Algorithm
Enzymatic End point/Spectrofluorometric