Web: | mayocliniclabs.com |
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Email: | mcl@mayo.edu |
Telephone: | 800-533-1710 |
International: | +1 855-379-3115 |
Values are valid only on day of printing. |
Diagnosis of adult individuals suspected of having transthyretin-associated familial amyloidosis
Mass spectrometry to evaluate transthyretin (TTR) protein structure is performed first. In all cases demonstrating a structural change, the TTR gene will be further analyzed by DNA sequence analysis. If no alterations are detected, the reflex full gene analysis will not be performed unless a specific request for ATTRZ / TTR Gene, Full Gene Analysis is submitted by the ordering physician or client.
Test ID | Reporting Name | Available Separately | Always Performed |
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ATTRZ | TTR Gene, Full Gene Analysis | Yes | No |
If familial amyloidosis by liquid chromatography-mass spectrometry is abnormal, DNA sequence will be performed and charged separately.
See Amyloidosis (Familial) Test Algorithm in Special Instructions.
Liquid Chromatography-Mass Spectrometry (LC-MS)