TEST CATALOG ORDERING & RESULTS SPECIMEN HANDLING CUSTOMER SERVICE EDUCATION & INSIGHTS
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Test ID: ACASM    
Pernicious Anemia Cascade, Serum

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Useful For Suggests clinical disorders or settings where the test may be helpful

Diagnosis of pernicious anemia

 

Diagnosis of vitamin B12 deficiency-associated neuropathy

Reflex Tests Lists tests that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial tests.

Test IDReporting NameAvailable SeparatelyAlways Performed
IFBPAIntrinsic Factor Blocking Ab, SYes, (order IFBA)No
MMAPAMethylmalonic Acid, QN, SYes, (order MMAS)No
GASTRGastrin, SYes, (order GAST)No

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

If the vitamin B12 concentration is less than 150 ng/L, then the intrinsic factor blocking antibody (IFBA) test is performed. If IFBA result is negative or indeterminate, then the gastrin test is performed.

If the vitamin B12 concentration is 150 to 400 ng/L, then the methylmalonic acid (MMA) test is performed. If the MMA result is greater than 0.40 nmol/mL, then the IFBA test is performed.

 

See Vitamin B12 Deficiency Evaluation in Special Instructions.

Special Instructions Library of PDFs including pertinent information and forms related to the test

Method Name A short description of the method used to perform the test

Immunoenzymatic Assay

NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Reporting Name Lists a shorter or abbreviated version of the Published Name for a test

Pernicious Anemia Cascade

Aliases Lists additional common names for a test, as an aid in searching

B12 Assay
B12 Deficiency
Cobalamin
Cobalamin Deficiency
Cyanocobalamin
Gastrin
Intrinsic Factor Blocking Antibody
Islet Cell Tumor
Methylmalonate
Methylmalonic Acid (MMA)
MMA (Methylmalonic Acid)
Schilling Testing (Alternative Strategy)
Soft-ACASM
Type 1 Intrinsic Factor Antibody
Vitamin B 12
CblC