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Test ID: PYRC    
Pyruvate, Spinal Fluid

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Useful For Suggests clinical disorders or settings where the test may be helpful

Investigating possible disorders of mitochondrial metabolism, when used in conjunction with cerebrospinal fluid lactate, collected at the same time, to determine the lactate-to-pyruvate (L:P) ratio

 

Evaluating patients with neurologic dysfunction and normal blood L:P ratios

Genetics Test Information Provides information that may help with selection of the correct genetic test or proper submission of the test request

The cerebrospinal fluid (CSF) lactate:pyruvate (L:P) ratio is considered a helpful (not diagnostic) tool in the evaluation of patients with possible disorders of mitochondrial metabolism, especially in patients with neurologic dysfunction and normal blood L:P ratios. Pyruvic acid levels alone have little clinical utility.

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

See Epilepsy: Unexplained Refractory and/or Familial Testing Algorithm

Special Instructions Library of PDFs including pertinent information and forms related to the test

Method Name A short description of the method used to perform the test

Spectrophotometry (SP)

NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Reporting Name Lists a shorter or abbreviated version of the Published Name for a test

Pyruvic Acid, CSF

Aliases Lists additional common names for a test, as an aid in searching

ETC
Mitochondrial Electron Transport Chain Defects
Mitochondrial Respiratory Chain Disorders
PC
PDH (Pyruvate Dehydrogenase) Deficiency
PDHC (Pyruvate Dehydrogenase Complex)
Pyruvate
Pyruvate Carboxylase Deficiency
Pyruvate Dehydrogenase (PDH) Deficiency
Pyruvate Dehydrogenase Complex (PDHC)
Lactate to Pyruvate Ratio (lactate [test ID LABF] must be ordered separately on the same spinal fluid)
L:P