Test Catalog

Test ID: LNGPR    
Lung Cancer-Targeted Gene Panel with Rearrangement, Tumor

Useful For Suggests clinical disorders or settings where the test may be helpful

Identifying lung tumors that may respond to targeted therapies by assessing multiple gene targets simultaneously in EGFR, BRAF, KRAS, HRAS, NRAS, ALK, ERBB2, MET, ALK, ROS1, RET, and NTRK1 genes


Diagnosis and management of patients with lung cancer

Genetics Test Information Provides information that may help with selection of the correct genetic test or proper submission of the test request

This test uses targeted next-generation sequencing to evaluate for somatic mutations within the EGFR, BRAF, KRAS, HRAS, NRAS, ALK, ERBB2, and MET genes. Next-generation sequencing is also used to identify rearrangements (fusions) involving ALK, ROS1, RET, and NTRK1. See Targeted Gene Regions Interrogated by Lung Panel and Activated/Partner Gene Breakpoints Resulting in Targeted Fusion Transcripts Interrogated by Lung Panel in Special Instructions for details regarding the targeted gene regions evaluated by this test.


Of note, this test is performed to evaluate for somatic mutations and rearrangements (fusions) within solid tumor samples. This test is not intended for use for hematological malignancies. Additionally, this test does not assess for germline alterations within the genes listed.


Evaluates formalin-fixed, paraffin-embedded tumor or cytology slides from patients with lung cancer for gene mutations and rearrangements (fusions) to identify candidates for targeted therapy.


Current data suggests that the efficacy of EGFR-targeted therapies in patients with non-small cell lung cancer is limited to tumors with mutations in the EGFR gene.


Current data suggests that lung carcinomas with ALK rearrangements may be sensitive to ALK inhibitors.


This test identifies activating exon 14 splice site mutations in MET.

Additional Tests Lists tests that are always performed, at an additional charge, with the initial tests.

Test IDReporting NameAvailable SeparatelyAlways Performed
SLIRVSlide Review in MGNo, (Bill Only)Yes

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

When this test is ordered, slide review will always be performed at an additional charge.

Special Instructions Library of PDFs including pertinent information and forms related to the test

Method Name A short description of the method used to perform the test

Polymerase Chain Reaction (PCR)-Based Next Generation Sequencing

NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.


Reporting Name Lists a shorter or abbreviated version of the Published Name for a test

Lung Panel with Rearrangement Tumor

Aliases Lists additional common names for a test, as an aid in searching

Lung cancer panel
Lung cancer rearrangement
Lung cancer fusion
Lung panel
Lung tumor panel
Tumor panel
Oncology panel
Next Gen Sequencing Test