Test Catalog

Test ID: LPCBS    
Lysophosphatidylcholines by LC MS/MS, Blood Spot

Useful For Suggests clinical disorders or settings where the test may be helpful

Second-tier newborn screen for X-linked adrenoleukodystrophy (X-ALD)

Genetics Test Information Provides information that may help with selection of the correct genetic test or proper submission of the test request

This test is used as a second-tier newborn screen for X-linked adrenoleukodystrophy (X-ALD).

Highlights

Testing for C24:0 lysophosphatidylcholines (LPC) and C26:0 LPC can aid in the diagnosis of X-linked adrenoleukodystrophy (X-ALD) as well as other types of peroxisomal disorders.

 

Analysis of LPCs in a blood spot test is a useful second-tier newborn screen test for X-ALD.

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

For more information, see the following documents in Special Instructions:

-Newborn Screening Act Sheet X-linked Adrenoleukodystrophy: Increased Very Long Chain Fatty Acids

-Newborn Screen Follow-up for X-linked Adrenoleukodystrophy

Special Instructions Library of PDFs including pertinent information and forms related to the test

Method Name A short description of the method used to perform the test

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Reporting Name Lists a shorter or abbreviated version of the Published Name for a test

LysoPC by LC MS/MS, BS

Aliases Lists additional common names for a test, as an aid in searching

Adrenoleukodystrophy (ALD)
Adrenomyeloneuropathy
LDSBS
LSD Screen
LSDBS
Lysosomal Storage Disorder Screen
Peroxisomal biogenesis disorders
X-linked adrenoleukodystrophy (XALD)
Zellweger Spectrum Syndrome (ZSS)
Zellweger Syndrome