Test Catalog

Test Id : LDPU

Limited Drug Profile, 3 Drug Classes, Immunoassay, Random, Urine

Useful For
Suggests clinical disorders or settings where the test may be helpful

Detecting drug use involving barbiturates, cocaine, and tetrahydrocannabinol

 

This test is not intended for use in employment-related testing.

Testing Algorithm
Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

Testing begins with screening tests for drugs of abuse including barbiturates, cocaine, and tetrahydrocannabinol.

 

Positive results can be confirmed and quantitated by definitive methods (gas chromatography-mass spectrometry for barbiturates, cocaine and metabolites, and tetrahydrocannabinol metabolite) at an additional charge.

Method Name
A short description of the method used to perform the test

Only orderable as part of profile. For more information see CSMHU / Controlled Substance Monitoring Hybrid Drug Panel, 20 Drug Classes, High-Resolution Mass Spectrometry and Immunoassay Screen, Random, Urine.

 

Screened by Immunoassay

NY State Available
Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Reporting Name
Lists a shorter or abbreviated version of the Published Name for a test

Limited Drug Panel, 3, IA, U

Testing Algorithm
Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

Testing begins with screening tests for drugs of abuse including barbiturates, cocaine, and tetrahydrocannabinol.

 

Positive results can be confirmed and quantitated by definitive methods (gas chromatography-mass spectrometry for barbiturates, cocaine and metabolites, and tetrahydrocannabinol metabolite) at an additional charge.

Specimen Type
Describes the specimen type validated for testing

Urine

Ordering Guidance

The test does not screen for drug classes other than those listed above.

Specimen Required
Defines the optimal specimen required to perform the test and the preferred volume to complete testing

Only orderable as part of profile. For more information see CSMHU / Controlled Substance Monitoring Hybrid Drug Panel, 20 Drug Classes, High-Resolution Mass Spectrometry and Immunoassay Screen, Random, Urine.

 

Container/Tube: Plastic, 10 mL tube

Specimen Volume: 2 mL

Collection Instructions:

1. Collect a random urine specimen.

2. No preservative

Specimen Minimum Volume
Defines the amount of sample necessary to provide a clinically relevant result as determined by the Testing Laboratory

0.5 mL

Reject Due To
Identifies specimen types and conditions that may cause the specimen to be rejected

  All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Specimen Stability Information
Provides a description of the temperatures required to transport a specimen to the performing laboratory, alternate acceptable temperatures are also included

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 14 days
Frozen 14 days
Ambient 72 hours

Useful For
Suggests clinical disorders or settings where the test may be helpful

Detecting drug use involving barbiturates, cocaine, and tetrahydrocannabinol

 

This test is not intended for use in employment-related testing.

Testing Algorithm
Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

Testing begins with screening tests for drugs of abuse including barbiturates, cocaine, and tetrahydrocannabinol.

 

Positive results can be confirmed and quantitated by definitive methods (gas chromatography-mass spectrometry for barbiturates, cocaine and metabolites, and tetrahydrocannabinol metabolite) at an additional charge.

Clinical Information
Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

This test uses the simple screening technique that involves immunologic testing for drugs by class.

 

All positive immunoassay screening results can be confirmed by gas chromatography-mass spectrometry (GC-MS) and quantitated if applicable.

 

This assay was designed to test for the following:

-Barbiturates

-Cocaine

-Tetrahydrocannabinol

Reference Values
Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

Only orderable as part of profile. For more information see CSMHU / Controlled Substance Monitoring Hybrid Drug Panel, 20 Drug Classes, High-Resolution Mass Spectrometry and Immunoassay Screen, Random, Urine.

 

Negative

Screening cutoff concentrations:

Barbiturates: 200 ng/mL

Cocaine (benzoylecgonine-cocaine metabolite): 150 ng/mL

Tetrahydrocannabinol carboxylic acid: 50 ng/mL

 

This report is intended for use in clinical monitoring or management of patients. It is not intended for use in employment-related testing.

Interpretation
Provides information to assist in interpretation of the test results

For information about drug testing, including estimated detection times, see Drugs of Abuse Testing.

Cautions
Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances

No significant cautionary statements

Clinical Reference
Recommendations for in-depth reading of a clinical nature

1. Physicians' Desk Reference: 60th ed. Medical Economics Company; 2006

2. Bruntman LL Lazo JS, Parker KL, eds: Goodman and Gilman's: The Pharmacological Basis of Therapeutics. 11th ed. McGraw-Hill Book Company; 2006

3. Langman LJ, Bechtel L, Meier BM, Holstege CP: Clinical toxicology In: Rifai N, Horwath AR, Wittwer CT, eds. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. 6th ed. Elsevier; 2018:832-887

4. Jannetto PJ, Bratanow NC, Clark WA, et al: Executive summary: American Association of Clinical Chemistry Laboratory Medicine Practice Guideline-using clinical laboratory tests to monitor drug therapy in pain management patients. J Appl Lab Med. 2018 Jan 1;2(4):489-526

Method Description
Describes how the test is performed and provides a method-specific reference

The barbiturate, cocaine metabolite, and tetrahydrocannabinol metabolite assays are based on the kinetic interaction of microparticles in a solution as measured by changes in light transmission. In the absence of sample drug, soluble drug conjugates bind to antibody-bound microparticles, causing the formation of particle aggregates. As the aggregation reaction proceeds in the absence of sample drug, the absorbance increases. When a urine sample contains the drug in question, this drug competes with the drug derivative conjugate for microparticle-bound antibody. Antibody bound to sample drug is no longer available to promote particle aggregation, and subsequent particle lattice formation is inhibited. The presence of sample drug diminishes the increasing absorbance in proportion to the concentration of drug in the sample. Sample drug content is determined relative to the value obtained for a known cutoff concentration of drug.(Package inserts: Barbiturates. Roche Diagnostics; 11/2017; Cannabinoids. Roche Diagnostics; 11/2017; Cocaine. Roche Diagnostics; 11/2017)

PDF Report
Indicates whether the report includes an additional document with charts, images or other enriched information

No

Day(s) Performed
Outlines the days the test is performed. This field reflects the day that the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time before the test is performed. Some tests are listed as continuously performed, which means that assays are performed multiple times during the day.

Monday through Friday

Report Available
The interval of time (receipt of sample at Mayo Clinic Laboratories to results available) taking into account standard setup days and weekends. The first day is the time that it typically takes for a result to be available. The last day is the time it might take, accounting for any necessary repeated testing.

Same day/1 to 2 days

Specimen Retention Time
Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded

14 days

Performing Laboratory Location
Indicates the location of the laboratory that performs the test

Rochester

Fees
Several factors determine the fee charged to perform a test. Contact your U.S. or International Regional Manager for information about establishing a fee schedule or to learn more about resources to optimize test selection.

  • Authorized users can sign in to Test Prices for detailed fee information.
  • Clients without access to Test Prices can contact Customer Service 24 hours a day, seven days a week.
  • Prospective clients should contact their Regional Manager. For assistance, contact Customer Service.

Test Classification
Provides information regarding the medical device classification for laboratory test kits and reagents. Tests may be classified as cleared or approved by the US Food and Drug Administration (FDA) and used per manufacturer instructions, or as products that do not undergo full FDA review and approval, and are then labeled as an Analyte Specific Reagent (ASR) product.

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information
Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Clinic Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.

CPT codes are provided by the performing laboratory.

80307

LOINC® Information

Test Id Test Order Name Order LOINC Value
LDPU Limited Drug Panel, 3, IA, U 69739-1
Result Id Test Result Name Result LOINC Value
Result LOINC Value Tooltip
615289 Barbiturates 19270-8
615290 Cocaine 19359-9
615291 Tetrahydrocannabinol 19415-9

Test Setup Resources

Setup Files
Test setup information contains test file definition details to support order and result interfacing between Mayo Clinic Laboratories and your Laboratory Information System.

Excel | Pdf

Sample Reports
Normal and Abnormal sample reports are provided as references for report appearance.

Normal Reports | Abnormal Reports

SI Sample Reports
International System (SI) of Unit reports are provided for a limited number of tests. These reports are intended for international account use and are only available through MayoLINK accounts that have been defined to receive them.

SI Normal Reports | SI Abnormal Reports