TEST CATALOG ORDERING & RESULTS SPECIMEN HANDLING CUSTOMER SERVICE EDUCATION & INSIGHTS
Test Catalog

Test ID: AIHL    
Aminoglycoside-Induced Hearing Loss, Targeted Variant Testing, Droplet Digital PCR, Varies

Useful For Suggests clinical disorders or settings where the test may be helpful

Identification of individuals who may be at risk for aminoglycoside-induced hearing loss (AIHL)

 

Establishing a diagnosis of late-onset sensorineural hearing loss associated with aminoglycoside exposure

 

Identifying mitochondrial variants associated with AIHL, allowing for predictive testing of at-risk family members

Genetics Test Information Provides information that may help with selection of the correct genetic test or proper submission of the test request

This test detects 2 mitochondrial gene RNR1 (MT-RNR1) variants, m.1555A>G and m.1494C>T, which are the most common variants associated with aminoglycoside induced ototoxicity.

Highlights

This test uses droplet digital polymerase chain reaction to evaluate for the presence of 2 mitochondrial variants associated with aminoglycoside-induced hearing loss.

Special Instructions Library of PDFs including pertinent information and forms related to the test

Method Name A short description of the method used to perform the test

Droplet Digital Polymerase Chain Reaction (ddPCR)

NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Reporting Name Lists a shorter or abbreviated version of the Published Name for a test

Aminoglycoside-Induced Hearing Loss

Aliases Lists additional common names for a test, as an aid in searching

Aminoglycoside-induced hearing loss
Aminoglycoside ototoxicity
Deafness, aminoglycoside-induced
MT-RNR1 m.1494C>T
MT-RNR1 m.1555A>G