Web: | mayocliniclabs.com |
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Email: | mcl@mayo.edu |
Telephone: | 800-533-1710 |
International: | +1 855-379-3115 |
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Measurement of biotin in serum
Assessment of biotin concentrations in individuals taking biotin supplements
Investigation of unexpected results from immunoassays that utilize biotin-streptavidin detection methods
This test is not useful as a screen for biotinidase deficiency.
Serum biotin is usually at relatively low endogenous concentrations but can be found at high concentrations if vitamin and herbal supplements containing biotin are taken.
This test measures free biotin concentrations in serum and can be used to determine if a patient's high biotin concentrations are likely from biotin supplementation or treatment.
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) Stable Isotope Dilution Analysis