Test Id : SULFU
Sulfate, 24 Hour, Urine
Useful For
Suggests clinical disorders or settings where the test may be helpful
Assessing the nutrition intake of animal protein
The calculation of urinary supersaturation of various crystals or stones
Method Name
A short description of the method used to perform the test
High-Pressure Ion Chromatography (HPIC)
NY State Available
Indicates the status of NY State approval and if the test is orderable for NY State clients.
Reporting Name
Lists a shorter or abbreviated version of the Published Name for a test
Aliases
Lists additional common names for a test, as an aid in searching
Sulfate
Specimen Type
Describes the specimen type validated for testing
Urine
Necessary Information
24-Hour volume (in milliliters) is required.
ORDER QUESTIONS AND ANSWERS
| Question ID | Description | Answers |
|---|---|---|
| TM89 | Collection Duration | |
| VL71 | Urine Volume |
Specimen Required
Defines the optimal specimen required to perform the test and the preferred volume to complete testing
Supplies: Sarstedt 5 mL Aliquot Tube (T914)
Container/Tube: Plastic, 5-mL urine tube
Specimen Volume: 4 mL
Collection Instructions:
1. Collect urine for 24 hours.
2. Collection instructions with no preservative:
-Specimen must be kept refrigerated during and after collection.
3. Collection instructions with preservative:
a. If preservative is not added before collection, the specimen must be kept refrigerated until preservative is added.
b. Preservative must be added within 4 hours of the end of collection.
4. Specimen pH should be between 4.5 and 8 and will stay in this range if kept refrigerated. Specimens with pH >8 indicate bacterial contamination, and testing will be cancelled. Do not attempt to adjust pH as it will adversely affect results.
Additional Information: See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens for multiple collections.
Special Instructions
Library of PDFs including pertinent information and forms related to the test
Forms
If not ordering electronically, complete, print, and send a Renal Diagnostics Test Request (T830) with the specimen.
Urine Preservative Collection Options
Note: If the specimen has been refrigerated during the entirety of the collection, the addition of preservative must occur within 4 hours of completion of the collection.
| Ambient | No |
| Refrigerate | Preferred |
| Frozen | OK |
| 50% Acetic Acid | No |
| Boric Acid | OK |
| Diazolidinyl Urea | OK |
| 6M Hydrochloric Acid | No |
| 6M Nitric Acid | No |
| Sodium Carbonate | OK |
| Thymol | No |
| Toluene | No |
Specimen Minimum Volume
Defines the amount of sample necessary to provide a clinically relevant result as determined by the testing laboratory. The minimum volume is sufficient for one attempt at testing.
1 mL
Reject Due To
Identifies specimen types and conditions that may cause the specimen to be rejected
Specimen Stability Information
Provides a description of the temperatures required to transport a specimen to the performing laboratory, alternate acceptable temperatures are also included
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Urine | Refrigerated (preferred) | 14 days | |
| Frozen | 14 days |
Useful For
Suggests clinical disorders or settings where the test may be helpful
Assessing the nutrition intake of animal protein
The calculation of urinary supersaturation of various crystals or stones
Clinical Information
Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test
Urinary sulfate is a reflection of dietary protein intake, particularly meat, fish,
Sulfate is a major anion in the urine that has significant affinity for cations and
Reference Values
Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.
7-47 mmol/24 hours
Interpretation
Provides information to assist in interpretation of the test results
Urinary sulfate is a reflection of dietary protein intake, particularly of
It also is used in the calculation of urinary supersaturation of various
Cautions
Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances
No significant cautionary statements
Clinical Reference
Recommendations for in-depth reading of a clinical nature
1. Rodgers A, Gauvin D, Edeh S, et al. Sulfate but not thiosulfate reduces calculated and measured urinary ionized calcium and supersaturation: implications for the treatment of calcium renal stones. PLoS ONE. 2014;9(7):e103602. doi:10.1371/journal.pone.0103602
2. Magee EA, Curno R, Edmond LM, Cummings JH. Contribution of dietary protein and inorganic sulfur to urinary sulfate: toward a biomarker of inorganic sulfur intake. Am J Clin Nutr. 2004;80(1):137-142
3. Houterman S, van Faassen A, Ocke MC, et al. Is urinary sulfate a biomarker for the intake of animal protein and meat?. Cancer Lett. 1997;114(1-2):295-296
Method Description
Describes how the test is performed and provides a method-specific reference
A high pressure ion chromatography system (HPICS) utilizes an anion exchange column to separate sulfate from other anions present in urine. Detection of sulfate is done by conductivity change as eluent flows through a conductivity cell of a conductivity detector. The Thermo IC system is operated through a PC computer using thermo Chromeleon 7 software.(Christison T, Lopez L. Determination of Inorganic Anions in Acid Rain Using a Dedicated High-Pressure Capillary Ion Chromatography System. Technical Note 124 Thermo Scientific; 2016)
PDF Report
Indicates whether the report includes an additional document with charts, images or other enriched information
Day(s) Performed
Outlines the days the test is performed. This field reflects the day that the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time before the test is performed. Some tests are listed as continuously performed, which means that assays are performed multiple times during the day.
Monday through Friday
Report Available
The interval of time (receipt of sample at Mayo Clinic Laboratories to results available) taking into account standard setup days and weekends. The first day is the time that it typically takes for a result to be available. The last day is the time it might take, accounting for any necessary repeated testing.
Specimen Retention Time
Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded
Performing Laboratory Location
Indicates the location of the laboratory that performs the test
Fees :
Several factors determine the fee charged to perform a test. Contact your U.S. or International Regional Manager for information about establishing a fee schedule or to learn more about resources to optimize test selection.
- Authorized users can sign in to Test Prices for detailed fee information.
- Clients without access to Test Prices can contact Customer Service 24 hours a day, seven days a week.
- Prospective clients should contact their account representative. For assistance, contact Customer Service.
Test Classification
Provides information regarding the medical device classification for laboratory test kits and reagents. Tests may be classified as cleared or approved by the US Food and Drug Administration (FDA) and used per manufacturer instructions, or as products that do not undergo full FDA review and approval, and are then labeled as an Analyte Specific Reagent (ASR) product.
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.
CPT Code Information
Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Clinic Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.
CPT codes are provided by the performing laboratory.
CPT codes are provided by the performing laboratory.
84392
LOINC® Information
Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the order and results codes of this test. LOINC values are provided by the performing laboratory.
| Test Id | Test Order Name | Order LOINC Value |
|---|---|---|
| SULFU | Sulfate, 24 Hr, U | 26889-6 |
| Result Id | Test Result Name |
Result LOINC Value
Applies only to results expressed in units of measure originally reported by the performing laboratory. These values do not apply to results that are converted to other units of measure.
|
|---|---|---|
| SLF_U | Sulfate, 24 Hr, U | 26889-6 |
| TM89 | Collection Duration | 13362-9 |
| VL71 | Urine Volume | 3167-4 |
| SUL_C | Sulfate Concentration, 24 Hr, U | 12920-5 |