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Test Catalog

Test ID: PCDEC    
Pediatric Autoimmune Central Nervous System Disorders Evaluation, Spinal Fluid

Useful For Suggests clinical disorders or settings where the test may be helpful

Evaluating children with autoimmune central nervous system disorders using spinal fluid specimens

Profile Information A profile is a group of laboratory tests that are ordered and performed together under a single Mayo Test ID. Profile information lists the test performed, inclusive of the test fee, when a profile is ordered and includes reporting names and individual availability.

Test IDReporting NameAvailable SeparatelyAlways Performed
PCCIPeds Autoimmune CNS Interp, CSFNoYes
ANN1CAnti-Neuronal Nuclear Ab, Type 1NoYes
CS2CCCASPR2-IgG CBA, CSFNoYes
DPPICDPPX Ab IFA, CSFNoYes
GABCCGABA-B-R Ab CBA, CSFNoYes
GD65CGAD65 Ab Assay, CSFYesYes
GFAICGFAP IFA, CSFNoYes
LG1CCLGI1-IgG CBA, CSFNoYes
GL1ICmGluR1 Ab IFA, CSFNoYes
NMDCCNMDA-R Ab CBA, CSFNoYes
NMOFCNMO/AQP4 FACS, CSFYesYes
PCTRCPurkinje Cell Cytoplasmc Ab Type TrNoYes

Reflex Tests Lists tests that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial tests.

Test IDReporting NameAvailable SeparatelyAlways Performed
AGN1CAnti-Glial Nuclear Ab, Type 1NoNo
AGNBCAGNA-1 Immunoblot, CSFNoNo
AMIBCAmphiphysin Immunoblot, CSFNoNo
AMPCCAMPA-R Ab CBA, CSFNoNo
AMPHCAmphiphysin Ab, CSFNoNo
AMPICAMPA-R Ab IF Titer Assay, CSFNoNo
AN1BCANNA-1 Immunoblot, CSFNoNo
AN2BCANNA-2 Immunoblot, CSFNoNo
ANN2CAnti-Neuronal Nuclear Ab, Type 2NoNo
ANN3CAnti-Neuronal Nuclear Ab, Type 3NoNo
DPPCCDPPX Ab CBA, CSFNoNo
DPPTCDPPX Ab IFA Titer, CSFNoNo
GABICGABA-B-R Ab IF Titer Assay, CSFNoNo
GFACCGFAP CBA, CSFNoNo
GFATCGFAP IFA Titer, CSFNoNo
GL1CCmGluR1 Ab CBA, CSFNoNo
GL1TCmGluR1 Ab IFA Titer, CSFNoNo
NMDICNMDA-R Ab IF Titer Assay, CSFNoNo
NMOTCNMO/AQP4 FACS Titer, CSFNoNo
PC1BCPCA-1 Immunoblot, CSFNoNo
PCA1CPurkinje Cell Cytoplasmic Ab Type 1NoNo
PCA2CPurkinje Cell Cytoplasmic Ab Type 2NoNo
PCTBCPCA-Tr Immunoblot, CSFNoNo

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

If indirect immunofluorescence assay (IFA) patterns suggest ANNA-1 antibody, then ANNA-1 immunoblot and ANNA-2 immunoblot are performed at an additional charge.

 

If IFA patterns suggest ANNA-2 antibody, then ANNA-2 immunoblot, ANNA-1 immunoblot, and ANNA-2 antibody IFA are performed at an additional charged.

 

If IFA patterns suggest ANNA-3 antibody, then ANNA-3 IFA is performed at an additional charge.

 

If IFA patterns suggest PCA-1 antibody, then PCA-1 immunoblot and PCA-1 IFA are performed at an additional charge.

 

If IFA patterns suggest PCA-2 antibody, then PCA-2 IFA is performed at an additional charge.

 

If IFA patterns suggest PCA-Tr antibody, then PCA-Tr immunoblot is performed at an additional charge.

 

If IFA pattern suggests amphiphysin antibody, then amphiphysin immunoblot and amphiphysin antibody IFA titer are performed at an additional charge.

 

If IFA pattern suggests AGNA antibody, then AGNA immunoblot and AGNA antibody IFA titer are performed at an additional charge.

 

If IFA pattern suggests NMDA-R antibody, then NMDA-R IFA titer is performed at an additional charge.

 

If IFA pattern suggests AMPA-R antibody, then AMPA-R antibody cell-binding assay (CBA) and AMPA-R IFA are performed at an additional charge.

 

If IFA pattern suggests GABA-B-R antibody, then GABA-B-R IFA titer is performed at an additional charge.

 

If IFA pattern suggests DPPX antibody, then DPPX antibody CBA and DPPX IFA titer are performed at an additional charge.

 

If IFA pattern suggests mGluR1 antibody, then mGluR1antibody CBA and mGluR1 IFA titer are performed at an additional charge.

 

If IFA pattern suggests GFAP antibody, then GFAP antibody CBA and GFAP IFA titer are performed at an additional charge.

 

If NMO/AQP4-IgG FACS screen assay requires further investigation, then NMO/AQP4-IgG FACS titration assay is performed at an additional charge.

 

See Pediatric Autoimmune Central Nervous System Disorders Evaluation Algorithm-Spinal Fluid in Special Instructions.

Special Instructions Library of PDFs including pertinent information and forms related to the test

Method Name A short description of the method used to perform the test

CS2CC, DPPCC, GABCC, AMPCC, GFACC, GL1CC, LG1CC, NMDCC: Cell-Binding Assay (CBA)

 

NMOFC, NMOTC: Flow Cytometry (FACS)

 

AGN1C, AMPIC, ANN1C, ANN2C, ANN3C, DPPIC, DPPTC, GABIC, GFAIC, GFATC, GL1IC, GL1TC, NMDIC, PCA1C, PCA2C, PCTRC: Indirect Immunofluorescence (IFA)

 

GD65C: Radioimmunoassay (RIA)

 

AGNBC, AMIBC, AN1BC, AN2BC, PC1BC, PC2BC: Immunoblot (IB)

NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Reporting Name Lists a shorter or abbreviated version of the Published Name for a test

Peds Autoimmune CNS Eval, CSF

Aliases Lists additional common names for a test, as an aid in searching

Encephalitis
Myelitis
Encephalopathy
Myelopathy, pediatric
Myelopathy, child